Effects of lithium and valproate on oxidative stress and behavioral changes induced by administration of m-AMPH

Abstract In the last years our research group has studied and validated the animal model of mania induced by dextroamphetamine ( d -AMPH). Considering the lack of animal models of mania reported in the literature; this study evaluated the possibilities to validate the animal model induced by methamp...

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Veröffentlicht in:	Psychiatry research 2012-08, Vol.198 (3), p.521-526
Hauptverfasser:	da-Rosa, Dayane D, Valvassori, Samira S, Steckert, Amanda V, Ornell, Felipe, Ferreira, Camila L, Lopes-Borges, Jéssica, Varela, Roger B, Dal-Pizzol, Felipe, Andersen, Monica L, Quevedo, João
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Animal model of mania Animals Antimanic Agents - pharmacology Antimanic Agents - therapeutic use Biological and medical sciences Bipolar Disorder - drug therapy Bipolar Disorder - metabolism Bipolar Disorder - prevention & control Bipolar Disorder - psychology Brain - drug effects Brain - metabolism Disease Models, Animal Dose-Response Relationship, Drug Lithium Lithium Compounds - pharmacology Lithium Compounds - therapeutic use Male Mania Medical sciences Methamphetamine Mood disorders Motor Activity - drug effects Neuropharmacology Oxidative stress Oxidative Stress - drug effects Pharmacology. Drug treatments Protein Carbonylation - drug effects Psychiatry Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychopharmacology Rats Rats, Wistar Thiobarbituric Acid Reactive Substances - metabolism Valproate Valproic Acid - pharmacology Valproic Acid - therapeutic use
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