Genetic structure of hepatitis B and C virus population circulating among healthy and high risk of parenteral contamination individuals in Azerbaijan

Considering that information on genetical features of hepatitis B (HBV) and hepatitis C (HCV) viruses populations, circulating in Azerbaijan remains limited, authors by means of adequate serological and molecular-genetical methods defined major genetical parameters of HBV and HCV, identified among b...

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Veröffentlicht in:Georgian medical news 2012-10 (211), p.46-49
Hauptverfasser: Mamedov, M K, Dadasheva, A E
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Dadasheva, A E
description Considering that information on genetical features of hepatitis B (HBV) and hepatitis C (HCV) viruses populations, circulating in Azerbaijan remains limited, authors by means of adequate serological and molecular-genetical methods defined major genetical parameters of HBV and HCV, identified among blood donors living in Azerbaijan and persons from groups with high risk of contamination with HBV and HCV. It was established that population of HBV is presented by dominating "wild" variant of HBV and mutant variants of HBV, defective on ability of producing HBeAg, HBcAg and even HBsAg. Thus more than 90% of HBV isolates belonged to D genotype, and less, than 10% - to A genotype. It is shown that population of HCV is presented by three genotypes: "1", "2" and "3", and the ratio of identification frequencies of these genotypes made approximately 71%:9%:20%, accordingly.
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subjects Azerbaijan
Blood Donors
Genetics, Population
Hepacivirus - genetics
Hepacivirus - pathogenicity
Hepatitis B - epidemiology
Hepatitis B - genetics
Hepatitis B - transmission
Hepatitis B e Antigens - genetics
Hepatitis B Surface Antigens - genetics
Hepatitis B virus - genetics
Hepatitis B virus - pathogenicity
Hepatitis C - epidemiology
Hepatitis C - genetics
Hepatitis C - transmission
Humans
title Genetic structure of hepatitis B and C virus population circulating among healthy and high risk of parenteral contamination individuals in Azerbaijan
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