The impact of cidofovir treatment on viral loads in adult recurrent respiratory papillomatosis

Cidofovir is an antiviral agent used in the therapy of recurrent respiratory papillomatosis (RRP). In this study, we hypothesized that cidofovir is effective in decreasing the viral load of human papillomavirus (HPV). We established a type specific real-time PCR and measured HPV DNA loads. The cours...

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Veröffentlicht in:	European archives of oto-rhino-laryngology 2012-12, Vol.269 (12), p.2543-2548
Hauptverfasser:	Mikolajczak, S., Quante, G., Weissenborn, S., Wafaisade, A., Wieland, U., Lüers, J. C., Klussmann, J. P., Beutner, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiviral Agents - therapeutic use Cytosine - analogs & derivatives Cytosine - therapeutic use DNA, Viral - analysis Female Head and Neck Surgery Human papillomavirus 11 Human papillomavirus 6 Humans Laryngeal Neoplasms - drug therapy Laryngology Male Medicine Medicine & Public Health Middle Aged Neurosurgery Organophosphonates - therapeutic use Otorhinolaryngology Papillomavirus Infections - drug therapy Papillomavirus Infections - virology Real-Time Polymerase Chain Reaction Respiratory Tract Infections - drug therapy Respiratory Tract Infections - virology Retrospective Studies Viral Load - drug effects
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