Probiotics in neonatology
Probiotics are micro‐organisms that confer health benefits on the host. Postulated mechanisms include: increasing resistance of the mucosal barrier to migration of bacteria and their toxins by strengthening intestinal cell junctions, modification of host response to microbial products, augmentation...
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| Veröffentlicht in: | Journal of paediatrics and child health 2012-09, Vol.48 (9), p.777-783 |
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| container_end_page | 783 |
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| container_issue | 9 |
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| container_title | Journal of paediatrics and child health |
| container_volume | 48 |
| creator | Hickey, Leah Jacobs, Susan E Garland, Suzanne M |
| description | Probiotics are micro‐organisms that confer health benefits on the host. Postulated mechanisms include: increasing resistance of the mucosal barrier to migration of bacteria and their toxins by strengthening intestinal cell junctions, modification of host response to microbial products, augmentation of immunoglobulin A mucosal responses, enhancement of enteral nutrition to inhibit the growth of pathogens; production of antimicrobial proteins; and competitive exclusion of potential pathogens. Published meta‐analyses and systematic reviews report the effects of probiotics on important clinical outcomes in neonates. This paper will review the evidence for probiotic supplementation in neonatology, with a focus on preterm infants. |
| doi_str_mv | 10.1111/j.1440-1754.2012.02508.x |
| format | Article |
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| identifier | ISSN: 1034-4810 |
| ispartof | Journal of paediatrics and child health, 2012-09, Vol.48 (9), p.777-783 |
| issn | 1034-4810 1440-1754 |
| language | eng |
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| source | MEDLINE; Wiley Journals |
| subjects | Clinical outcomes Dietary supplements Evidence-Based Medicine Humans Infant, Newborn necrotising enterocolitis Neonatal care Neonatology Newborn babies preterm/term infant Probiotics Probiotics - administration & dosage Probiotics - therapeutic use sepsis |
| title | Probiotics in neonatology |
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