Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility
Purpose To investigate the relationship between hyaluronan binding (HB) assay and pregnancy rates in intrauterine insemination (IUI) cycles. Methods This prospective cohort study was done in Hacettepe University, a tertiary care center for reproductive medicine. Seventy-one consecutive couples who s...
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| Veröffentlicht in: | Archives of gynecology and obstetrics 2012-12, Vol.286 (6), p.1577-1580 |
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| container_title | Archives of gynecology and obstetrics |
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| creator | Boynukalin, Fazilet Kubra Esinler, Ibrahim Guven, Suleyman Gunalp, Serdar |
| description | Purpose
To investigate the relationship between hyaluronan binding (HB) assay and pregnancy rates in intrauterine insemination (IUI) cycles.
Methods
This prospective cohort study was done in Hacettepe University, a tertiary care center for reproductive medicine. Seventy-one consecutive couples who suffered from unexplained infertility and underwent controlled ovarian hyperstimulation (COH) and IUI were enrolled into the study.
Results
From the 71 IUI patients, the clinical pregnancy rate was 14.1 % (10 of 71). HB ratio from the overall patient number was 48.6 ± 25.9. The mean HB ratio in pregnant and non-pregnant groups was comparable (50.2 ± 25.2 vs. 48.3 ± 26.2, respectively,
p
> 0.05).
Conclusions
Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility. |
| doi_str_mv | 10.1007/s00404-012-2476-2 |
| format | Article |
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To investigate the relationship between hyaluronan binding (HB) assay and pregnancy rates in intrauterine insemination (IUI) cycles.
Methods
This prospective cohort study was done in Hacettepe University, a tertiary care center for reproductive medicine. Seventy-one consecutive couples who suffered from unexplained infertility and underwent controlled ovarian hyperstimulation (COH) and IUI were enrolled into the study.
Results
From the 71 IUI patients, the clinical pregnancy rate was 14.1 % (10 of 71). HB ratio from the overall patient number was 48.6 ± 25.9. The mean HB ratio in pregnant and non-pregnant groups was comparable (50.2 ± 25.2 vs. 48.3 ± 26.2, respectively,
p
> 0.05).
Conclusions
Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility.</description><identifier>ISSN: 0932-0067</identifier><identifier>EISSN: 1432-0711</identifier><identifier>DOI: 10.1007/s00404-012-2476-2</identifier><identifier>PMID: 22832980</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Adult ; Biological Assay - methods ; Couples ; Endocrinology ; Female ; Gynecology ; Human Genetics ; Humans ; Hyaluronic Acid - metabolism ; Infertility ; Infertility - therapy ; Insemination, Artificial ; Male ; Medicine ; Medicine & Public Health ; Obstetrics/Perinatology/Midwifery ; Ovulation Induction ; Predictive Value of Tests ; Pregnancy ; Pregnancy Rate ; Prospective Studies ; Reproductive Medicine ; Semen Analysis ; Spermatozoa - metabolism ; Young Adult</subject><ispartof>Archives of gynecology and obstetrics, 2012-12, Vol.286 (6), p.1577-1580</ispartof><rights>Springer-Verlag 2012</rights><rights>Archives of Gynecology and Obstetrics is a copyright of Springer, (2012). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-74ea545acdf78e744af1c6b8f3f888c14420b11d6cf04c2d012c767b26ee0ea73</citedby><cites>FETCH-LOGICAL-c372t-74ea545acdf78e744af1c6b8f3f888c14420b11d6cf04c2d012c767b26ee0ea73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00404-012-2476-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00404-012-2476-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22832980$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Boynukalin, Fazilet Kubra</creatorcontrib><creatorcontrib>Esinler, Ibrahim</creatorcontrib><creatorcontrib>Guven, Suleyman</creatorcontrib><creatorcontrib>Gunalp, Serdar</creatorcontrib><title>Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility</title><title>Archives of gynecology and obstetrics</title><addtitle>Arch Gynecol Obstet</addtitle><addtitle>Arch Gynecol Obstet</addtitle><description>Purpose
To investigate the relationship between hyaluronan binding (HB) assay and pregnancy rates in intrauterine insemination (IUI) cycles.
Methods
This prospective cohort study was done in Hacettepe University, a tertiary care center for reproductive medicine. Seventy-one consecutive couples who suffered from unexplained infertility and underwent controlled ovarian hyperstimulation (COH) and IUI were enrolled into the study.
Results
From the 71 IUI patients, the clinical pregnancy rate was 14.1 % (10 of 71). HB ratio from the overall patient number was 48.6 ± 25.9. The mean HB ratio in pregnant and non-pregnant groups was comparable (50.2 ± 25.2 vs. 48.3 ± 26.2, respectively,
p
> 0.05).
Conclusions
Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility.</description><subject>Adult</subject><subject>Biological Assay - methods</subject><subject>Couples</subject><subject>Endocrinology</subject><subject>Female</subject><subject>Gynecology</subject><subject>Human Genetics</subject><subject>Humans</subject><subject>Hyaluronic Acid - metabolism</subject><subject>Infertility</subject><subject>Infertility - therapy</subject><subject>Insemination, Artificial</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Obstetrics/Perinatology/Midwifery</subject><subject>Ovulation Induction</subject><subject>Predictive Value of Tests</subject><subject>Pregnancy</subject><subject>Pregnancy Rate</subject><subject>Prospective Studies</subject><subject>Reproductive Medicine</subject><subject>Semen Analysis</subject><subject>Spermatozoa - metabolism</subject><subject>Young Adult</subject><issn>0932-0067</issn><issn>1432-0711</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kUFP3DAQhS1EBVvgB_RSWeLSS9qx49jmiBCUlZB6KWfLcSaLUdZO7UQ0_75eQlupUk8z1vvmeexHyAcGnxmA-pIBBIgKGK-4ULLiR2TDRM0rUIwdkw1cHXqQ6pS8z_kZCqi1PCGnnOuaX2nYkHi_2GFOMdhAWx86H3bU5mwX2kXMNMSJjgk7717rrmBuoclORfOBbh-31C1uWE8uzuOhffHTE50D_hwH6wN2ResxTX7w03JO3vV2yHjxVs_I493t95v76uHb1-3N9UPlasWnSgm0jWis63qlUQlhe-Zkq_u611o7JgSHlrFOuh6E4115mVNStVwiAlpVn5FPq--Y4o8Z82T2PjscBhswztkwJlhTN0KKgl7-gz7HOYWyneFcMq0BGlYotlIuxZwT9mZMfm_TYhiYQxpmTcOUVcwhDcPLzMc357ndY_dn4vf3F4CvQC5S2GH6e_X_XX8BAbGVuw</recordid><startdate>20121201</startdate><enddate>20121201</enddate><creator>Boynukalin, Fazilet Kubra</creator><creator>Esinler, Ibrahim</creator><creator>Guven, Suleyman</creator><creator>Gunalp, Serdar</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20121201</creationdate><title>Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility</title><author>Boynukalin, Fazilet Kubra ; Esinler, Ibrahim ; Guven, Suleyman ; Gunalp, Serdar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-74ea545acdf78e744af1c6b8f3f888c14420b11d6cf04c2d012c767b26ee0ea73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Biological Assay - methods</topic><topic>Couples</topic><topic>Endocrinology</topic><topic>Female</topic><topic>Gynecology</topic><topic>Human Genetics</topic><topic>Humans</topic><topic>Hyaluronic Acid - metabolism</topic><topic>Infertility</topic><topic>Infertility - therapy</topic><topic>Insemination, Artificial</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Obstetrics/Perinatology/Midwifery</topic><topic>Ovulation Induction</topic><topic>Predictive Value of Tests</topic><topic>Pregnancy</topic><topic>Pregnancy Rate</topic><topic>Prospective Studies</topic><topic>Reproductive Medicine</topic><topic>Semen Analysis</topic><topic>Spermatozoa - metabolism</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Boynukalin, Fazilet Kubra</creatorcontrib><creatorcontrib>Esinler, Ibrahim</creatorcontrib><creatorcontrib>Guven, Suleyman</creatorcontrib><creatorcontrib>Gunalp, Serdar</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of gynecology and obstetrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boynukalin, Fazilet Kubra</au><au>Esinler, Ibrahim</au><au>Guven, Suleyman</au><au>Gunalp, Serdar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility</atitle><jtitle>Archives of gynecology and obstetrics</jtitle><stitle>Arch Gynecol Obstet</stitle><addtitle>Arch Gynecol Obstet</addtitle><date>2012-12-01</date><risdate>2012</risdate><volume>286</volume><issue>6</issue><spage>1577</spage><epage>1580</epage><pages>1577-1580</pages><issn>0932-0067</issn><eissn>1432-0711</eissn><abstract>Purpose
To investigate the relationship between hyaluronan binding (HB) assay and pregnancy rates in intrauterine insemination (IUI) cycles.
Methods
This prospective cohort study was done in Hacettepe University, a tertiary care center for reproductive medicine. Seventy-one consecutive couples who suffered from unexplained infertility and underwent controlled ovarian hyperstimulation (COH) and IUI were enrolled into the study.
Results
From the 71 IUI patients, the clinical pregnancy rate was 14.1 % (10 of 71). HB ratio from the overall patient number was 48.6 ± 25.9. The mean HB ratio in pregnant and non-pregnant groups was comparable (50.2 ± 25.2 vs. 48.3 ± 26.2, respectively,
p
> 0.05).
Conclusions
Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>22832980</pmid><doi>10.1007/s00404-012-2476-2</doi><tpages>4</tpages></addata></record> |
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| ispartof | Archives of gynecology and obstetrics, 2012-12, Vol.286 (6), p.1577-1580 |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Biological Assay - methods Couples Endocrinology Female Gynecology Human Genetics Humans Hyaluronic Acid - metabolism Infertility Infertility - therapy Insemination, Artificial Male Medicine Medicine & Public Health Obstetrics/Perinatology/Midwifery Ovulation Induction Predictive Value of Tests Pregnancy Pregnancy Rate Prospective Studies Reproductive Medicine Semen Analysis Spermatozoa - metabolism Young Adult |
| title | Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility |
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