Computational Modeling, Synthesis, and Antioxidant Potential of Novel Phenylcarbamoylbenzoic Acid Analogs in Combating Oxidative Stress

A new series of phenylcarbamoylbenzoic acid analogs were designed, synthesized, and evaluated for their in vitro antioxidant activity, aiming to find a lead for the treatment of oxidative stress. The target compounds were prepared by substituting the core phenylcarbamoylbenzoic acid moiety with cert...

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Veröffentlicht in:	Archiv der Pharmazie (Weinheim) 2012-11, Vol.345 (11), p.902-910
Hauptverfasser:	Bayoumi, Waleed A., Elsayed, Magda A., Baraka, Hany N., Abou-zeid, Laila
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - chemistry Antioxidant activity Antioxidants Antioxidants - chemical synthesis Antioxidants - chemistry Antioxidants - pharmacology Benzoates - chemical synthesis Benzoates - chemistry Benzoates - pharmacology Drug Design Food science Humans Models, Molecular Molecular Docking Simulation Molecular modeling Oxidative stress Oxidative Stress - drug effects Phenylcarbamoylbenzoic acid Structure-Activity Relationship Synthesis
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