Antimicrobial profile of crude extracts Calotropis procera and Centella asiatica against some important pathogens

To investigate in vitro antimicrobial activity of aerial parts of Calotropis procera and Centella asatica Linn., that have been popularly used as folk medicines. The organic solvent plant extracts are tested on the various microorganisms including bacteria and fungi using agar well diffusion technique. The length of the inhibition zone was measured in millimeters from the edge of the well to the edge of the inhibition zone. C. procera showed significant to moderate activity against (14 mm) Pseudomonas marginalis and (21 mm) Streptococcus mutans with 100 mg/ml DMSO plant drug concentration. The results of (MICs) values are lowest at 66 and highest at 152 mg/ml for C. procera whereas 0 to 155 mg/ml for C. asatica. The extracts were assessed in an effort to validate the potential activity of the medicinal plants against microbes.