Acepromazine pharmacokinetics: A forensic perspective

Acepromazine (ACP) is a useful therapeutic drug, but is a prohibited substance in competition horses. The illicit use of ACP is difficult to detect due to its rapid metabolism, so this study investigated the ACP metabolite 2-(1-hydroxyethyl)promazine sulphoxide (HEPS) as a potential forensic marker....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The veterinary journal (1997) 2012-10, Vol.194 (1), p.48-54
Hauptverfasser:	Schneiders, Fiona I., Noble, Glenys K., Boston, Raymond C., Dunstan, Anthony J., Sillence, Martin N., McKinney, Andrew R.
Format:	Artikel
Sprache:	eng
Schlagworte:	acepromazine Acepromazine - blood Acepromazine - pharmacokinetics Acepromazine - urine Animals Area Under Curve blood Dopamine Antagonists - blood Dopamine Antagonists - pharmacokinetics Dopamine Antagonists - urine Drug metabolism drug therapy Equine Excretion time Forensic Medicine - methods geldings Half-Life Horses - blood Horses - metabolism intravenous injection liquid chromatography Male maleates mass spectrometry metabolites pharmacokinetics Promazine - analogs & derivatives Promazine - blood Promazine - metabolism Sedative urine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!