Diagnostic accuracy of global myocardial deformation indexes in coronary artery disease: a velocity vector imaging study
The aim of our study was to assess the diagnostic accuracy of a global longitudinal strain and strain rate (GLS, GLSR) and mean radial strain and strain rate (MRS, MRSR) of the left ventricle to predict multivessel disease. In 113 patients, who underwent coronary angiography, left ventricular deform...
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| Veröffentlicht in: | The International Journal of Cardiovascular Imaging 2012-12, Vol.28 (8), p.1931-1942 |
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| container_title | The International Journal of Cardiovascular Imaging |
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| creator | Valocik, Gabriel Valocikova, Ivana Mitro, Peter Fojtikova, Livia Druzbacka, Ludmila Kristofova, Beata Juhas, Stanislav Kolesar, Adrian Sabol, Frantisek |
| description | The aim of our study was to assess the diagnostic accuracy of a global longitudinal strain and strain rate (GLS, GLSR) and mean radial strain and strain rate (MRS, MRSR) of the left ventricle to predict multivessel disease. In 113 patients, who underwent coronary angiography, left ventricular deformation was analysed by speckle-tracking based velocity vector imaging. In three standard apical views strain and strain rate curves were generated corresponding with two opposite basal, mid, and apical segments. The negative peaks of systolic strain and strain rate from 18 curves were averaged as GLS and GLSR. Similarly, in short axis view 6 negative systolic peaks were averaged and considered as MRS and MRSR. Four subgroups were defined: (1) without significant coronary stenosis, 0-vessel disease (0VD), (2) single-vessel disease (1VD), (3) double-vessel disease (2VD), and (4) triple-vessel disease (3VD). In comparison with patients without significant coronary artery disease, all deformation indexes were significantly decreased in patients with 3VD. The left ventricular ejection fraction (LVEF) and wall motion score index (WMSI) showed lower significance level as deformation parameters. MRSR was the strongest predictor of multivessel disease. Receiver-operating characteristic curves (ROC) showed that MRSR had the highest diagnostic accuracy. Comparing ROC areas, MRSR had significantly higher diagnostic accuracy than LVEF and WMSI. The results of our study show that global deformation indexes have a good diagnostic accuracy in differentiating multivessel disease. MRSR tended to be better in identification of 3VD than traditional indexes of global and regional left ventricular function. |
| doi_str_mv | 10.1007/s10554-012-0025-5 |
| format | Article |
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In 113 patients, who underwent coronary angiography, left ventricular deformation was analysed by speckle-tracking based velocity vector imaging. In three standard apical views strain and strain rate curves were generated corresponding with two opposite basal, mid, and apical segments. The negative peaks of systolic strain and strain rate from 18 curves were averaged as GLS and GLSR. Similarly, in short axis view 6 negative systolic peaks were averaged and considered as MRS and MRSR. Four subgroups were defined: (1) without significant coronary stenosis, 0-vessel disease (0VD), (2) single-vessel disease (1VD), (3) double-vessel disease (2VD), and (4) triple-vessel disease (3VD). In comparison with patients without significant coronary artery disease, all deformation indexes were significantly decreased in patients with 3VD. The left ventricular ejection fraction (LVEF) and wall motion score index (WMSI) showed lower significance level as deformation parameters. MRSR was the strongest predictor of multivessel disease. Receiver-operating characteristic curves (ROC) showed that MRSR had the highest diagnostic accuracy. Comparing ROC areas, MRSR had significantly higher diagnostic accuracy than LVEF and WMSI. The results of our study show that global deformation indexes have a good diagnostic accuracy in differentiating multivessel disease. MRSR tended to be better in identification of 3VD than traditional indexes of global and regional left ventricular function.</description><identifier>ISSN: 1569-5794</identifier><identifier>EISSN: 1573-0743</identifier><identifier>EISSN: 1875-8312</identifier><identifier>DOI: 10.1007/s10554-012-0025-5</identifier><identifier>PMID: 22327941</identifier><identifier>CODEN: IJCIBI</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Cardiac Imaging ; Cardiology ; Coronary Angiography ; Coronary Artery Disease - diagnostic imaging ; Coronary Artery Disease - physiopathology ; Echocardiography, Doppler ; Female ; Humans ; Image Interpretation, Computer-Assisted ; Imaging ; Linear Models ; Logistic Models ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Multivariate Analysis ; Myocardial Contraction ; Observer Variation ; Odds Ratio ; Original Paper ; Predictive Value of Tests ; Radiology ; Reproducibility of Results ; Retrospective Studies ; ROC Curve ; Severity of Illness Index ; Stroke Volume ; Ventricular Function, Left</subject><ispartof>The International Journal of Cardiovascular Imaging, 2012-12, Vol.28 (8), p.1931-1942</ispartof><rights>Springer Science+Business Media, B.V. 2012</rights><rights>Springer Science+Business Media Dordrecht 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-d81c7195a04c2e27256b0678819dcb34a84594856fed7181394dc15243dfe0223</citedby><cites>FETCH-LOGICAL-c372t-d81c7195a04c2e27256b0678819dcb34a84594856fed7181394dc15243dfe0223</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10554-012-0025-5$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10554-012-0025-5$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,781,785,27929,27930,41493,42562,51324</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22327941$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Valocik, Gabriel</creatorcontrib><creatorcontrib>Valocikova, Ivana</creatorcontrib><creatorcontrib>Mitro, Peter</creatorcontrib><creatorcontrib>Fojtikova, Livia</creatorcontrib><creatorcontrib>Druzbacka, Ludmila</creatorcontrib><creatorcontrib>Kristofova, Beata</creatorcontrib><creatorcontrib>Juhas, Stanislav</creatorcontrib><creatorcontrib>Kolesar, Adrian</creatorcontrib><creatorcontrib>Sabol, Frantisek</creatorcontrib><title>Diagnostic accuracy of global myocardial deformation indexes in coronary artery disease: a velocity vector imaging study</title><title>The International Journal of Cardiovascular Imaging</title><addtitle>Int J Cardiovasc Imaging</addtitle><addtitle>Int J Cardiovasc Imaging</addtitle><description>The aim of our study was to assess the diagnostic accuracy of a global longitudinal strain and strain rate (GLS, GLSR) and mean radial strain and strain rate (MRS, MRSR) of the left ventricle to predict multivessel disease. In 113 patients, who underwent coronary angiography, left ventricular deformation was analysed by speckle-tracking based velocity vector imaging. In three standard apical views strain and strain rate curves were generated corresponding with two opposite basal, mid, and apical segments. The negative peaks of systolic strain and strain rate from 18 curves were averaged as GLS and GLSR. Similarly, in short axis view 6 negative systolic peaks were averaged and considered as MRS and MRSR. Four subgroups were defined: (1) without significant coronary stenosis, 0-vessel disease (0VD), (2) single-vessel disease (1VD), (3) double-vessel disease (2VD), and (4) triple-vessel disease (3VD). In comparison with patients without significant coronary artery disease, all deformation indexes were significantly decreased in patients with 3VD. The left ventricular ejection fraction (LVEF) and wall motion score index (WMSI) showed lower significance level as deformation parameters. MRSR was the strongest predictor of multivessel disease. Receiver-operating characteristic curves (ROC) showed that MRSR had the highest diagnostic accuracy. Comparing ROC areas, MRSR had significantly higher diagnostic accuracy than LVEF and WMSI. The results of our study show that global deformation indexes have a good diagnostic accuracy in differentiating multivessel disease. MRSR tended to be better in identification of 3VD than traditional indexes of global and regional left ventricular function.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cardiac Imaging</subject><subject>Cardiology</subject><subject>Coronary Angiography</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Coronary Artery Disease - physiopathology</subject><subject>Echocardiography, Doppler</subject><subject>Female</subject><subject>Humans</subject><subject>Image Interpretation, Computer-Assisted</subject><subject>Imaging</subject><subject>Linear Models</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Myocardial Contraction</subject><subject>Observer Variation</subject><subject>Odds Ratio</subject><subject>Original Paper</subject><subject>Predictive Value of Tests</subject><subject>Radiology</subject><subject>Reproducibility of Results</subject><subject>Retrospective Studies</subject><subject>ROC Curve</subject><subject>Severity of Illness Index</subject><subject>Stroke Volume</subject><subject>Ventricular Function, Left</subject><issn>1569-5794</issn><issn>1573-0743</issn><issn>1875-8312</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kUtLxTAQhYMovn-AGwm4cVNN0qRp3cn1CYIbXYfcZFpyaRtNWrn996ZcFRFcnSH55kwmB6ETSi4oIfIyUiIEzwhlGSFMZGIL7VMh84xInm_PdVFlQlZ8Dx3EuCIJIizfRXuM5Swd0320vnG66X0cnMHamDFoM2Ff46b1S93ibvJGB-tSaaH2odOD8z12vYU1xKTY-OB7HSaswwBJrIugI1xhjT-g9cYNUyrM4AN2nW5c3-A4jHY6Qju1biMcf-kher27fVk8ZE_P94-L66fM5JINmS2pkbQSmnDDgEkmiiUpZFnSypplznXJRcVLUdRgJS1pXnFrqGA8tzWQtOchOt_4vgX_PkIcVOeigbbVPfgxKkpZMTtwktCzP-jKj6FPr5spLplMn54ouqFM8DEGqNVbSJuFSVGi5ljUJhaVYlFzLEqkntMv53HZgf3p-M4hAWwDxHTVNxB-jf7X9RNpF5f7</recordid><startdate>20121201</startdate><enddate>20121201</enddate><creator>Valocik, Gabriel</creator><creator>Valocikova, Ivana</creator><creator>Mitro, Peter</creator><creator>Fojtikova, Livia</creator><creator>Druzbacka, Ludmila</creator><creator>Kristofova, Beata</creator><creator>Juhas, Stanislav</creator><creator>Kolesar, Adrian</creator><creator>Sabol, Frantisek</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7Z</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20121201</creationdate><title>Diagnostic accuracy of global myocardial deformation indexes in coronary artery disease: a velocity vector imaging study</title><author>Valocik, Gabriel ; 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In 113 patients, who underwent coronary angiography, left ventricular deformation was analysed by speckle-tracking based velocity vector imaging. In three standard apical views strain and strain rate curves were generated corresponding with two opposite basal, mid, and apical segments. The negative peaks of systolic strain and strain rate from 18 curves were averaged as GLS and GLSR. Similarly, in short axis view 6 negative systolic peaks were averaged and considered as MRS and MRSR. Four subgroups were defined: (1) without significant coronary stenosis, 0-vessel disease (0VD), (2) single-vessel disease (1VD), (3) double-vessel disease (2VD), and (4) triple-vessel disease (3VD). In comparison with patients without significant coronary artery disease, all deformation indexes were significantly decreased in patients with 3VD. The left ventricular ejection fraction (LVEF) and wall motion score index (WMSI) showed lower significance level as deformation parameters. MRSR was the strongest predictor of multivessel disease. Receiver-operating characteristic curves (ROC) showed that MRSR had the highest diagnostic accuracy. Comparing ROC areas, MRSR had significantly higher diagnostic accuracy than LVEF and WMSI. The results of our study show that global deformation indexes have a good diagnostic accuracy in differentiating multivessel disease. MRSR tended to be better in identification of 3VD than traditional indexes of global and regional left ventricular function.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>22327941</pmid><doi>10.1007/s10554-012-0025-5</doi><tpages>12</tpages></addata></record> |
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| subjects | Adult Aged Aged, 80 and over Cardiac Imaging Cardiology Coronary Angiography Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - physiopathology Echocardiography, Doppler Female Humans Image Interpretation, Computer-Assisted Imaging Linear Models Logistic Models Male Medicine Medicine & Public Health Middle Aged Multivariate Analysis Myocardial Contraction Observer Variation Odds Ratio Original Paper Predictive Value of Tests Radiology Reproducibility of Results Retrospective Studies ROC Curve Severity of Illness Index Stroke Volume Ventricular Function, Left |
| title | Diagnostic accuracy of global myocardial deformation indexes in coronary artery disease: a velocity vector imaging study |
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