Impact of age and sex on carotid and peripheral arterial wall thickness in humans
Background Although previous studies have reported age‐related wall thickening in carotid arteries, it is not clear whether this is a systemic phenomenon which is also apparent in peripheral conduit arteries or whether conduit wall thickness (WT) changes occur to a similar degree in men and women. A...
Gespeichert in:
| Veröffentlicht in: | Acta Physiologica 2012-12, Vol.206 (4), p.220-228 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 228 |
|---|---|
| container_issue | 4 |
| container_start_page | 220 |
| container_title | Acta Physiologica |
| container_volume | 206 |
| creator | van den Munckhof, I. Scholten, R. Cable, N. T. Hopman, M. T. E. Green, D. J. Thijssen, D. H. J. |
| description | Background
Although previous studies have reported age‐related wall thickening in carotid arteries, it is not clear whether this is a systemic phenomenon which is also apparent in peripheral conduit arteries or whether conduit wall thickness (WT) changes occur to a similar degree in men and women.
Aim
To determine whether sex modifies the impact of ageing on WT or wall‐to‐lumen ratio (W:L) in atherosclerosis‐prone (i.e. carotid artery, femoral, superficial femoral, popliteal artery) and atherosclerosis‐resistant (i.e. brachial artery) conduit arteries.
Methods
We included 30 young (23 ± 2 year; 15M : 15F) and 31 older (70 ± 5 year; 18M : 13F) healthy subjects. High‐resolution ultrasound was used to measure diameter, WT and wall‐to‐lumen ratio (W/L) in all arteries.
Results
Older subjects had increased WT and W/L in the carotid, femoral, superficial femoral, popliteal and brachial arteries (all P |
| doi_str_mv | 10.1111/j.1748-1716.2012.02457.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1125254019</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2801452321</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5167-a822cb79c30f3c58e449ea9483061e02f4c1e5156408df7628b581c5e6f5992e3</originalsourceid><addsrcrecordid>eNqNkF1rFDEUhgex2NL2L0hABG9mmu9kboSl6rawVAVtwZuQzZ5xs52vJjN0--_NdLcreGVuck7ynPc9vFmGCC5IOhebgiiuc6KILCgmtMCUC1VsX2Unh4_Xhxrr4-w8xg3GCSWMU_omO6YMay1weZJ9v2566wbUVcj-BmTbFYqwRV2LnA3d4FfPTz0E368h2BrZMKQmFY-2rtGw9u6-hRiRb9F6bGwbz7KjytYRzvf3afbzy-cfl1f54uv8-nK2yJ0gUuVWU-qWqnQMV8wJDZyXYEuuGZYEMK24IyCIkBzrVaUk1UuhiRMgK1GWFNhp9mGn24fuYYQ4mMZHB3VtW-jGaAihggqOSZnQd_-gm24MbdouUcmCaixxovSOcqGLMUBl-uAbG54MwRNHzMZMoZopYDMlb56TN9s0-nZvMC4bWB0GX3JOwPs9YKOzdRVs63z8y8nkL4lK3Mcd9-hrePrvBczs29VsKpNAvhPwcYDtQcCGeyMVU8Lc3cwNvfnF1Pz2k1mwP37uqxU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1115628060</pqid></control><display><type>article</type><title>Impact of age and sex on carotid and peripheral arterial wall thickness in humans</title><source>Access via Wiley Online Library</source><source>MEDLINE</source><creator>van den Munckhof, I. ; Scholten, R. ; Cable, N. T. ; Hopman, M. T. E. ; Green, D. J. ; Thijssen, D. H. J.</creator><creatorcontrib>van den Munckhof, I. ; Scholten, R. ; Cable, N. T. ; Hopman, M. T. E. ; Green, D. J. ; Thijssen, D. H. J.</creatorcontrib><description>Background
Although previous studies have reported age‐related wall thickening in carotid arteries, it is not clear whether this is a systemic phenomenon which is also apparent in peripheral conduit arteries or whether conduit wall thickness (WT) changes occur to a similar degree in men and women.
Aim
To determine whether sex modifies the impact of ageing on WT or wall‐to‐lumen ratio (W:L) in atherosclerosis‐prone (i.e. carotid artery, femoral, superficial femoral, popliteal artery) and atherosclerosis‐resistant (i.e. brachial artery) conduit arteries.
Methods
We included 30 young (23 ± 2 year; 15M : 15F) and 31 older (70 ± 5 year; 18M : 13F) healthy subjects. High‐resolution ultrasound was used to measure diameter, WT and wall‐to‐lumen ratio (W/L) in all arteries.
Results
Older subjects had increased WT and W/L in the carotid, femoral, superficial femoral, popliteal and brachial arteries (all P < 0.05). Compared with women, men demonstrated larger diameter and WT (both P < 0.01) across all arteries. Sex did not impact upon age‐related changes in WT or W/L (P = 0.39 and 0.43 respectively).
Conclusion
Our data suggest that age‐related wall thickening, evident in the carotid artery, is also apparent in the arteries of the upper and lower limbs. The impact of age on wall thickening did not differ between men and women. These data support the presence of systemic increases in WT and W/L with age in apparently healthy humans, independent of sex.</description><identifier>ISSN: 1748-1708</identifier><identifier>EISSN: 1748-1716</identifier><identifier>DOI: 10.1111/j.1748-1716.2012.02457.x</identifier><identifier>PMID: 23088509</identifier><language>eng</language><publisher>Oxford: Blackwell Publishing Ltd</publisher><subject>Adult ; Age Distribution ; Aged ; ageing ; Analysis of Variance ; arterial remodelling ; Arteries - pathology ; atherosclerosis ; Atherosclerosis - pathology ; Biological and medical sciences ; cardiovascular disease ; Female ; Fundamental and applied biological sciences. Psychology ; Humans ; Male ; Risk Factors ; Sex Factors ; Vertebrates: anatomy and physiology, studies on body, several organs or systems ; wall-lumen ratio ; Young Adult</subject><ispartof>Acta Physiologica, 2012-12, Vol.206 (4), p.220-228</ispartof><rights>2012 The Authors Acta Physiologica © 2012 Scandinavian Physiological Society</rights><rights>2015 INIST-CNRS</rights><rights>2012 The Authors Acta Physiologica © 2012 Scandinavian Physiological Society.</rights><rights>Copyright © 2012 Scandinavian Physiological Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5167-a822cb79c30f3c58e449ea9483061e02f4c1e5156408df7628b581c5e6f5992e3</citedby><cites>FETCH-LOGICAL-c5167-a822cb79c30f3c58e449ea9483061e02f4c1e5156408df7628b581c5e6f5992e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1748-1716.2012.02457.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1748-1716.2012.02457.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,782,786,1419,27933,27934,45583,45584</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26603617$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23088509$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>van den Munckhof, I.</creatorcontrib><creatorcontrib>Scholten, R.</creatorcontrib><creatorcontrib>Cable, N. T.</creatorcontrib><creatorcontrib>Hopman, M. T. E.</creatorcontrib><creatorcontrib>Green, D. J.</creatorcontrib><creatorcontrib>Thijssen, D. H. J.</creatorcontrib><title>Impact of age and sex on carotid and peripheral arterial wall thickness in humans</title><title>Acta Physiologica</title><addtitle>Acta Physiol</addtitle><description>Background
Although previous studies have reported age‐related wall thickening in carotid arteries, it is not clear whether this is a systemic phenomenon which is also apparent in peripheral conduit arteries or whether conduit wall thickness (WT) changes occur to a similar degree in men and women.
Aim
To determine whether sex modifies the impact of ageing on WT or wall‐to‐lumen ratio (W:L) in atherosclerosis‐prone (i.e. carotid artery, femoral, superficial femoral, popliteal artery) and atherosclerosis‐resistant (i.e. brachial artery) conduit arteries.
Methods
We included 30 young (23 ± 2 year; 15M : 15F) and 31 older (70 ± 5 year; 18M : 13F) healthy subjects. High‐resolution ultrasound was used to measure diameter, WT and wall‐to‐lumen ratio (W/L) in all arteries.
Results
Older subjects had increased WT and W/L in the carotid, femoral, superficial femoral, popliteal and brachial arteries (all P < 0.05). Compared with women, men demonstrated larger diameter and WT (both P < 0.01) across all arteries. Sex did not impact upon age‐related changes in WT or W/L (P = 0.39 and 0.43 respectively).
Conclusion
Our data suggest that age‐related wall thickening, evident in the carotid artery, is also apparent in the arteries of the upper and lower limbs. The impact of age on wall thickening did not differ between men and women. These data support the presence of systemic increases in WT and W/L with age in apparently healthy humans, independent of sex.</description><subject>Adult</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>ageing</subject><subject>Analysis of Variance</subject><subject>arterial remodelling</subject><subject>Arteries - pathology</subject><subject>atherosclerosis</subject><subject>Atherosclerosis - pathology</subject><subject>Biological and medical sciences</subject><subject>cardiovascular disease</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Male</subject><subject>Risk Factors</subject><subject>Sex Factors</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><subject>wall-lumen ratio</subject><subject>Young Adult</subject><issn>1748-1708</issn><issn>1748-1716</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkF1rFDEUhgex2NL2L0hABG9mmu9kboSl6rawVAVtwZuQzZ5xs52vJjN0--_NdLcreGVuck7ynPc9vFmGCC5IOhebgiiuc6KILCgmtMCUC1VsX2Unh4_Xhxrr4-w8xg3GCSWMU_omO6YMay1weZJ9v2566wbUVcj-BmTbFYqwRV2LnA3d4FfPTz0E368h2BrZMKQmFY-2rtGw9u6-hRiRb9F6bGwbz7KjytYRzvf3afbzy-cfl1f54uv8-nK2yJ0gUuVWU-qWqnQMV8wJDZyXYEuuGZYEMK24IyCIkBzrVaUk1UuhiRMgK1GWFNhp9mGn24fuYYQ4mMZHB3VtW-jGaAihggqOSZnQd_-gm24MbdouUcmCaixxovSOcqGLMUBl-uAbG54MwRNHzMZMoZopYDMlb56TN9s0-nZvMC4bWB0GX3JOwPs9YKOzdRVs63z8y8nkL4lK3Mcd9-hrePrvBczs29VsKpNAvhPwcYDtQcCGeyMVU8Lc3cwNvfnF1Pz2k1mwP37uqxU</recordid><startdate>201212</startdate><enddate>201212</enddate><creator>van den Munckhof, I.</creator><creator>Scholten, R.</creator><creator>Cable, N. T.</creator><creator>Hopman, M. T. E.</creator><creator>Green, D. J.</creator><creator>Thijssen, D. H. J.</creator><general>Blackwell Publishing Ltd</general><general>Wiley-Blackwell</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7TS</scope><scope>7X8</scope></search><sort><creationdate>201212</creationdate><title>Impact of age and sex on carotid and peripheral arterial wall thickness in humans</title><author>van den Munckhof, I. ; Scholten, R. ; Cable, N. T. ; Hopman, M. T. E. ; Green, D. J. ; Thijssen, D. H. J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5167-a822cb79c30f3c58e449ea9483061e02f4c1e5156408df7628b581c5e6f5992e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Age Distribution</topic><topic>Aged</topic><topic>ageing</topic><topic>Analysis of Variance</topic><topic>arterial remodelling</topic><topic>Arteries - pathology</topic><topic>atherosclerosis</topic><topic>Atherosclerosis - pathology</topic><topic>Biological and medical sciences</topic><topic>cardiovascular disease</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Male</topic><topic>Risk Factors</topic><topic>Sex Factors</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><topic>wall-lumen ratio</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van den Munckhof, I.</creatorcontrib><creatorcontrib>Scholten, R.</creatorcontrib><creatorcontrib>Cable, N. T.</creatorcontrib><creatorcontrib>Hopman, M. T. E.</creatorcontrib><creatorcontrib>Green, D. J.</creatorcontrib><creatorcontrib>Thijssen, D. H. J.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>MEDLINE - Academic</collection><jtitle>Acta Physiologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van den Munckhof, I.</au><au>Scholten, R.</au><au>Cable, N. T.</au><au>Hopman, M. T. E.</au><au>Green, D. J.</au><au>Thijssen, D. H. J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of age and sex on carotid and peripheral arterial wall thickness in humans</atitle><jtitle>Acta Physiologica</jtitle><addtitle>Acta Physiol</addtitle><date>2012-12</date><risdate>2012</risdate><volume>206</volume><issue>4</issue><spage>220</spage><epage>228</epage><pages>220-228</pages><issn>1748-1708</issn><eissn>1748-1716</eissn><abstract>Background
Although previous studies have reported age‐related wall thickening in carotid arteries, it is not clear whether this is a systemic phenomenon which is also apparent in peripheral conduit arteries or whether conduit wall thickness (WT) changes occur to a similar degree in men and women.
Aim
To determine whether sex modifies the impact of ageing on WT or wall‐to‐lumen ratio (W:L) in atherosclerosis‐prone (i.e. carotid artery, femoral, superficial femoral, popliteal artery) and atherosclerosis‐resistant (i.e. brachial artery) conduit arteries.
Methods
We included 30 young (23 ± 2 year; 15M : 15F) and 31 older (70 ± 5 year; 18M : 13F) healthy subjects. High‐resolution ultrasound was used to measure diameter, WT and wall‐to‐lumen ratio (W/L) in all arteries.
Results
Older subjects had increased WT and W/L in the carotid, femoral, superficial femoral, popliteal and brachial arteries (all P < 0.05). Compared with women, men demonstrated larger diameter and WT (both P < 0.01) across all arteries. Sex did not impact upon age‐related changes in WT or W/L (P = 0.39 and 0.43 respectively).
Conclusion
Our data suggest that age‐related wall thickening, evident in the carotid artery, is also apparent in the arteries of the upper and lower limbs. The impact of age on wall thickening did not differ between men and women. These data support the presence of systemic increases in WT and W/L with age in apparently healthy humans, independent of sex.</abstract><cop>Oxford</cop><pub>Blackwell Publishing Ltd</pub><pmid>23088509</pmid><doi>10.1111/j.1748-1716.2012.02457.x</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1748-1708 |
| ispartof | Acta Physiologica, 2012-12, Vol.206 (4), p.220-228 |
| issn | 1748-1708 1748-1716 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1125254019 |
| source | Access via Wiley Online Library; MEDLINE |
| subjects | Adult Age Distribution Aged ageing Analysis of Variance arterial remodelling Arteries - pathology atherosclerosis Atherosclerosis - pathology Biological and medical sciences cardiovascular disease Female Fundamental and applied biological sciences. Psychology Humans Male Risk Factors Sex Factors Vertebrates: anatomy and physiology, studies on body, several organs or systems wall-lumen ratio Young Adult |
| title | Impact of age and sex on carotid and peripheral arterial wall thickness in humans |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-11-30T13%3A30%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Impact%20of%20age%20and%20sex%20on%20carotid%20and%20peripheral%20arterial%20wall%20thickness%20in%20humans&rft.jtitle=Acta%20Physiologica&rft.au=van%20den%20Munckhof,%20I.&rft.date=2012-12&rft.volume=206&rft.issue=4&rft.spage=220&rft.epage=228&rft.pages=220-228&rft.issn=1748-1708&rft.eissn=1748-1716&rft_id=info:doi/10.1111/j.1748-1716.2012.02457.x&rft_dat=%3Cproquest_cross%3E2801452321%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1115628060&rft_id=info:pmid/23088509&rfr_iscdi=true |