Reprogramming mammalian somatic cells

Somatic cell nuclear transfer (SCNT), the technique commonly known as cloning, permits transformation of a somatic cell into an undifferentiated zygote with the potential to develop into a newborn animal (i.e., a clone). In somatic cells, chromatin is programmed to repress most genes and express som...

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Veröffentlicht in:	Theriogenology 2012-12, Vol.78 (9), p.1869-1886
Hauptverfasser:	Rodriguez-Osorio, N, Urrego, R, Cibelli, J.B, Eilertsen, K, Memili, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation chromatin Cloning, Organism Embryo Epigenesis, Genetic Epigenetics Gene Expression Regulation, Developmental gene overexpression genes IPSCs Mammals neonates Nuclear Transfer Techniques oocytes Somatic cell nuclear transfer somatic cells stem cells transcription factors zygote
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