Primary cauda equina lymphoma treated with high-dose methotrexate
A 69-year-old man presented with a very rare case of primary central nervous system lymphoma originating in the cauda equina manifesting as progressive paraparesis. The patient underwent a biopsy, and was treated with intravenous high-dose (3.5 g/m(2)) methotrexate chemotherapy and local irradiation...
Gespeichert in:
| Veröffentlicht in: | Neurologia medico-chirurgica 2012, Vol.52 (9), p.679-683 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 683 |
|---|---|
| container_issue | 9 |
| container_start_page | 679 |
| container_title | Neurologia medico-chirurgica |
| container_volume | 52 |
| creator | Iwasaki, Motoyuki Hida, Kazutoshi Yano, Shunsuke Aoyama, Takeshi Kaneko, Sadahiro Iwasaki, Yoshinobu |
| description | A 69-year-old man presented with a very rare case of primary central nervous system lymphoma originating in the cauda equina manifesting as progressive paraparesis. The patient underwent a biopsy, and was treated with intravenous high-dose (3.5 g/m(2)) methotrexate chemotherapy and local irradiation. Histological study revealed large B cell type lymphoma. Follow-up magnetic resonance imaging showed complete remission of the lesion, but the patient died of pneumonia at 18 months after the initial onset without tumor recurrence, so the efficacy of this strategy remains unknown. |
| doi_str_mv | 10.2176/nmc.52.679 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1125235139</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1125235139</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3029-a185380d47eeea24f63649bb64412b0e351dc7aec65e4c74a7f0e23e9df0d8873</originalsourceid><addsrcrecordid>eNo1jz1PwzAURS0EolHpwg9AHllSnj9iO2NVQUGqBAPMkWO_kEhxk8aJoP-eSC3THc7R1b2E3DNYc6bV0yG4dcbXSudXJGFC5qkBnl-TBKSG1DDIFmQVY1MCcGmkMPqWLLgAUMaohGw-hibY4USdnbyleJyag6XtKfR1FywdB7QjevrTjDWtm-869V1EGnCsu5n9zvCO3FS2jbi65JJ8vTx_bl_T_fvubbvZp07Mg1LLTCYMeKkR0XJZKaFkXpZKSsZLQJEx77RFpzKUTkurK0AuMPcVeGO0WJLHc28_dMcJ41iEJjpsW3vAbooFYzzjc4vIZ_Xhok5lQF_054_F_23xB_iGWZY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1125235139</pqid></control><display><type>article</type><title>Primary cauda equina lymphoma treated with high-dose methotrexate</title><source>J-STAGE Free</source><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Iwasaki, Motoyuki ; Hida, Kazutoshi ; Yano, Shunsuke ; Aoyama, Takeshi ; Kaneko, Sadahiro ; Iwasaki, Yoshinobu</creator><creatorcontrib>Iwasaki, Motoyuki ; Hida, Kazutoshi ; Yano, Shunsuke ; Aoyama, Takeshi ; Kaneko, Sadahiro ; Iwasaki, Yoshinobu</creatorcontrib><description>A 69-year-old man presented with a very rare case of primary central nervous system lymphoma originating in the cauda equina manifesting as progressive paraparesis. The patient underwent a biopsy, and was treated with intravenous high-dose (3.5 g/m(2)) methotrexate chemotherapy and local irradiation. Histological study revealed large B cell type lymphoma. Follow-up magnetic resonance imaging showed complete remission of the lesion, but the patient died of pneumonia at 18 months after the initial onset without tumor recurrence, so the efficacy of this strategy remains unknown.</description><identifier>ISSN: 0470-8105</identifier><identifier>EISSN: 1349-8029</identifier><identifier>DOI: 10.2176/nmc.52.679</identifier><identifier>PMID: 23006886</identifier><language>eng</language><publisher>Japan</publisher><subject>Aged ; Antimetabolites, Antineoplastic - administration & dosage ; Antimetabolites, Antineoplastic - therapeutic use ; Cauda Equina - pathology ; Cauda Equina - surgery ; Combined Modality Therapy ; Fatal Outcome ; Humans ; Hypesthesia - etiology ; Indexing in process ; Laminectomy ; Lymphoma, Large B-Cell, Diffuse - complications ; Lymphoma, Large B-Cell, Diffuse - drug therapy ; Lymphoma, Large B-Cell, Diffuse - radiotherapy ; Lymphoma, Large B-Cell, Diffuse - surgery ; Magnetic Resonance Imaging ; Male ; Methotrexate - administration & dosage ; Methotrexate - therapeutic use ; Paraparesis - etiology ; Peripheral Nervous System Neoplasms - complications ; Peripheral Nervous System Neoplasms - drug therapy ; Peripheral Nervous System Neoplasms - radiotherapy ; Peripheral Nervous System Neoplasms - surgery ; Pneumonia - complications ; Polyradiculopathy - etiology ; Radiotherapy, Adjuvant ; Remission Induction</subject><ispartof>Neurologia medico-chirurgica, 2012, Vol.52 (9), p.679-683</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3029-a185380d47eeea24f63649bb64412b0e351dc7aec65e4c74a7f0e23e9df0d8873</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,862,27911,27912</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23006886$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Iwasaki, Motoyuki</creatorcontrib><creatorcontrib>Hida, Kazutoshi</creatorcontrib><creatorcontrib>Yano, Shunsuke</creatorcontrib><creatorcontrib>Aoyama, Takeshi</creatorcontrib><creatorcontrib>Kaneko, Sadahiro</creatorcontrib><creatorcontrib>Iwasaki, Yoshinobu</creatorcontrib><title>Primary cauda equina lymphoma treated with high-dose methotrexate</title><title>Neurologia medico-chirurgica</title><addtitle>Neurol Med Chir (Tokyo)</addtitle><description>A 69-year-old man presented with a very rare case of primary central nervous system lymphoma originating in the cauda equina manifesting as progressive paraparesis. The patient underwent a biopsy, and was treated with intravenous high-dose (3.5 g/m(2)) methotrexate chemotherapy and local irradiation. Histological study revealed large B cell type lymphoma. Follow-up magnetic resonance imaging showed complete remission of the lesion, but the patient died of pneumonia at 18 months after the initial onset without tumor recurrence, so the efficacy of this strategy remains unknown.</description><subject>Aged</subject><subject>Antimetabolites, Antineoplastic - administration & dosage</subject><subject>Antimetabolites, Antineoplastic - therapeutic use</subject><subject>Cauda Equina - pathology</subject><subject>Cauda Equina - surgery</subject><subject>Combined Modality Therapy</subject><subject>Fatal Outcome</subject><subject>Humans</subject><subject>Hypesthesia - etiology</subject><subject>Indexing in process</subject><subject>Laminectomy</subject><subject>Lymphoma, Large B-Cell, Diffuse - complications</subject><subject>Lymphoma, Large B-Cell, Diffuse - drug therapy</subject><subject>Lymphoma, Large B-Cell, Diffuse - radiotherapy</subject><subject>Lymphoma, Large B-Cell, Diffuse - surgery</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Methotrexate - administration & dosage</subject><subject>Methotrexate - therapeutic use</subject><subject>Paraparesis - etiology</subject><subject>Peripheral Nervous System Neoplasms - complications</subject><subject>Peripheral Nervous System Neoplasms - drug therapy</subject><subject>Peripheral Nervous System Neoplasms - radiotherapy</subject><subject>Peripheral Nervous System Neoplasms - surgery</subject><subject>Pneumonia - complications</subject><subject>Polyradiculopathy - etiology</subject><subject>Radiotherapy, Adjuvant</subject><subject>Remission Induction</subject><issn>0470-8105</issn><issn>1349-8029</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1jz1PwzAURS0EolHpwg9AHllSnj9iO2NVQUGqBAPMkWO_kEhxk8aJoP-eSC3THc7R1b2E3DNYc6bV0yG4dcbXSudXJGFC5qkBnl-TBKSG1DDIFmQVY1MCcGmkMPqWLLgAUMaohGw-hibY4USdnbyleJyag6XtKfR1FywdB7QjevrTjDWtm-869V1EGnCsu5n9zvCO3FS2jbi65JJ8vTx_bl_T_fvubbvZp07Mg1LLTCYMeKkR0XJZKaFkXpZKSsZLQJEx77RFpzKUTkurK0AuMPcVeGO0WJLHc28_dMcJ41iEJjpsW3vAbooFYzzjc4vIZ_Xhok5lQF_054_F_23xB_iGWZY</recordid><startdate>2012</startdate><enddate>2012</enddate><creator>Iwasaki, Motoyuki</creator><creator>Hida, Kazutoshi</creator><creator>Yano, Shunsuke</creator><creator>Aoyama, Takeshi</creator><creator>Kaneko, Sadahiro</creator><creator>Iwasaki, Yoshinobu</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7TK</scope></search><sort><creationdate>2012</creationdate><title>Primary cauda equina lymphoma treated with high-dose methotrexate</title><author>Iwasaki, Motoyuki ; Hida, Kazutoshi ; Yano, Shunsuke ; Aoyama, Takeshi ; Kaneko, Sadahiro ; Iwasaki, Yoshinobu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3029-a185380d47eeea24f63649bb64412b0e351dc7aec65e4c74a7f0e23e9df0d8873</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Aged</topic><topic>Antimetabolites, Antineoplastic - administration & dosage</topic><topic>Antimetabolites, Antineoplastic - therapeutic use</topic><topic>Cauda Equina - pathology</topic><topic>Cauda Equina - surgery</topic><topic>Combined Modality Therapy</topic><topic>Fatal Outcome</topic><topic>Humans</topic><topic>Hypesthesia - etiology</topic><topic>Indexing in process</topic><topic>Laminectomy</topic><topic>Lymphoma, Large B-Cell, Diffuse - complications</topic><topic>Lymphoma, Large B-Cell, Diffuse - drug therapy</topic><topic>Lymphoma, Large B-Cell, Diffuse - radiotherapy</topic><topic>Lymphoma, Large B-Cell, Diffuse - surgery</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Methotrexate - administration & dosage</topic><topic>Methotrexate - therapeutic use</topic><topic>Paraparesis - etiology</topic><topic>Peripheral Nervous System Neoplasms - complications</topic><topic>Peripheral Nervous System Neoplasms - drug therapy</topic><topic>Peripheral Nervous System Neoplasms - radiotherapy</topic><topic>Peripheral Nervous System Neoplasms - surgery</topic><topic>Pneumonia - complications</topic><topic>Polyradiculopathy - etiology</topic><topic>Radiotherapy, Adjuvant</topic><topic>Remission Induction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Iwasaki, Motoyuki</creatorcontrib><creatorcontrib>Hida, Kazutoshi</creatorcontrib><creatorcontrib>Yano, Shunsuke</creatorcontrib><creatorcontrib>Aoyama, Takeshi</creatorcontrib><creatorcontrib>Kaneko, Sadahiro</creatorcontrib><creatorcontrib>Iwasaki, Yoshinobu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Neurosciences Abstracts</collection><jtitle>Neurologia medico-chirurgica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Iwasaki, Motoyuki</au><au>Hida, Kazutoshi</au><au>Yano, Shunsuke</au><au>Aoyama, Takeshi</au><au>Kaneko, Sadahiro</au><au>Iwasaki, Yoshinobu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary cauda equina lymphoma treated with high-dose methotrexate</atitle><jtitle>Neurologia medico-chirurgica</jtitle><addtitle>Neurol Med Chir (Tokyo)</addtitle><date>2012</date><risdate>2012</risdate><volume>52</volume><issue>9</issue><spage>679</spage><epage>683</epage><pages>679-683</pages><issn>0470-8105</issn><eissn>1349-8029</eissn><abstract>A 69-year-old man presented with a very rare case of primary central nervous system lymphoma originating in the cauda equina manifesting as progressive paraparesis. The patient underwent a biopsy, and was treated with intravenous high-dose (3.5 g/m(2)) methotrexate chemotherapy and local irradiation. Histological study revealed large B cell type lymphoma. Follow-up magnetic resonance imaging showed complete remission of the lesion, but the patient died of pneumonia at 18 months after the initial onset without tumor recurrence, so the efficacy of this strategy remains unknown.</abstract><cop>Japan</cop><pmid>23006886</pmid><doi>10.2176/nmc.52.679</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0470-8105 |
| ispartof | Neurologia medico-chirurgica, 2012, Vol.52 (9), p.679-683 |
| issn | 0470-8105 1349-8029 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1125235139 |
| source | J-STAGE Free; MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Aged Antimetabolites, Antineoplastic - administration & dosage Antimetabolites, Antineoplastic - therapeutic use Cauda Equina - pathology Cauda Equina - surgery Combined Modality Therapy Fatal Outcome Humans Hypesthesia - etiology Indexing in process Laminectomy Lymphoma, Large B-Cell, Diffuse - complications Lymphoma, Large B-Cell, Diffuse - drug therapy Lymphoma, Large B-Cell, Diffuse - radiotherapy Lymphoma, Large B-Cell, Diffuse - surgery Magnetic Resonance Imaging Male Methotrexate - administration & dosage Methotrexate - therapeutic use Paraparesis - etiology Peripheral Nervous System Neoplasms - complications Peripheral Nervous System Neoplasms - drug therapy Peripheral Nervous System Neoplasms - radiotherapy Peripheral Nervous System Neoplasms - surgery Pneumonia - complications Polyradiculopathy - etiology Radiotherapy, Adjuvant Remission Induction |
| title | Primary cauda equina lymphoma treated with high-dose methotrexate |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T04%3A25%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Primary%20cauda%20equina%20lymphoma%20treated%20with%20high-dose%20methotrexate&rft.jtitle=Neurologia%20medico-chirurgica&rft.au=Iwasaki,%20Motoyuki&rft.date=2012&rft.volume=52&rft.issue=9&rft.spage=679&rft.epage=683&rft.pages=679-683&rft.issn=0470-8105&rft.eissn=1349-8029&rft_id=info:doi/10.2176/nmc.52.679&rft_dat=%3Cproquest_pubme%3E1125235139%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1125235139&rft_id=info:pmid/23006886&rfr_iscdi=true |