Isobutanol production in engineered Saccharomyces cerevisiae by overexpression of 2-ketoisovalerate decarboxylase and valine biosynthetic enzymes

Engineering of Saccharomyces cerevisiae to produce advanced biofuels such as isobutanol has received much attention because this yeast has a natural capacity to produce higher alcohols. In this study, construction of isobutanol production systems was attempted by overexpression of effective 2-keto a...

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Veröffentlicht in:	Bioprocess and biosystems engineering 2012-11, Vol.35 (9), p.1467-1475
Hauptverfasser:	Lee, Won-Heong, Seo, Seung-Oh, Bae, Yi-Hyun, Nan, Hong, Jin, Yong-Su, Seo, Jin-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Acetolactate Mutase - biosynthesis 2-Acetolactate Mutase - genetics Acetolactate Synthase - biosynthesis Acetolactate Synthase - genetics Bacterial Proteins - biosynthesis Bacterial Proteins - genetics Biofuels Biological and medical sciences Biosynthesis Biotechnology Butanols - metabolism Carbon sources Carboxy-Lyases - biosynthesis Carboxy-Lyases - genetics Chemistry Chemistry and Materials Science Environmental Engineering/Biotechnology Ethanol Food Science Fundamental and applied biological sciences. Psychology Gene expression Genetic engineering Hydro-Lyases - biosynthesis Hydro-Lyases - genetics Industrial and Production Engineering Industrial Chemistry/Chemical Engineering Lactococcus lactis - enzymology Lactococcus lactis - genetics Metabolic Engineering Microorganisms Original Paper Saccharomyces cerevisiae Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - genetics Valine - biosynthesis Valine - genetics Yeasts
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