Chronic immune activation and decreased CD4 cell counts associated with hepatitis C infection in HIV-1 natural viral suppressors

We have established a cohort of natural viral suppressors (NVS) who can suppress HIV-1 replication to less than 400 copies/ml in the absence of therapy (similar to Elite Controllers/Elite Suppressors). Of the 59 patients currently in the NVS cohort, 45.8% have chronic hepatitis C virus (HCV) infecti...

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Veröffentlicht in:	AIDS (London) 2012-09, Vol.26 (15), p.1879-1884
Hauptverfasser:	SAJADI, Mohammad M, PULIJALA, Roopa, REDFIELD, Robert R, TALWANI, Rohit
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Biological and medical sciences CD4 Lymphocyte Count CD4-CD8 Ratio CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Cohort Studies Coinfection Female Hepacivirus - immunology Hepatitis C virus Hepatitis C, Chronic - immunology Hepatitis C, Chronic - physiopathology Hepatitis C, Chronic - virology HIV Seropositivity - immunology HIV Seropositivity - physiopathology HIV Seropositivity - virology HIV-1 - immunology Human immunodeficiency virus 1 Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Lymphocyte Activation - immunology Male Medical sciences Middle Aged RNA, Viral Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral hepatitis Viral Load Virus Replication - immunology
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