Iron and holotransferrin induce cAMP-dependent differentiation of Schwann cells

► We describe the effect of iron on myelin proteins in Schwann cells. ► We describe that iron promotes cAMP increase. ► We describe that iron promotes CREB phosphorylation. ► We describe that iron promotes the increase in MBP and P0 levels. ► We describe that iron promotes the increase in oxygen rea...

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Veröffentlicht in:	Neurochemistry international 2012-10, Vol.61 (5), p.798-806
Hauptverfasser:	Salis, C., Davio, C., Usach, V., Urtasun, N., Goitia, B., Martinez-Vivot, R., Pasquini, J.M., Setton-Avruj, C.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ammonium Animals Animals, Newborn Biological and medical sciences cAMP Cell Differentiation - drug effects Cell Differentiation - physiology Cells, Cultured CREB Cyclic AMP - physiology Ferric Compounds - pharmacology Fundamental and applied biological sciences. Psychology Holotransferrin Iron Iron - physiology PKA Quaternary Ammonium Compounds - pharmacology Rats Rats, Wistar Schwann cells Schwann Cells - drug effects Schwann Cells - physiology Transferrin - physiology Vertebrates: nervous system and sense organs
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