Down-regulation of NOD1 in neutrophils of periparturient dairy cows

Increased susceptibility of periparturient dairy cows to infectious diseases has been linked to neutrophil dysfunction. Cytoplasmic nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) mediate numerous aspects of innate immunity in humans and experimental animals. The authors hypoth...

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Veröffentlicht in:	Veterinary immunology and immunopathology 2012-11, Vol.150 (1-2), p.133-139
Hauptverfasser:	Tan, Xun, Li, Wen-Wen, Guo, Jing, Zhou, Ji-Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cattle - genetics Cattle - immunology Dairy cow Down-Regulation Female Flow Cytometry - veterinary Immunity, Innate - immunology Neutrophil Neutrophil Activation - genetics Neutrophil Activation - immunology Neutrophils - immunology Nod1 Signaling Adaptor Protein - genetics Nod1 Signaling Adaptor Protein - immunology Nucleotide-binding oligomerization domain-like receptor Oxidative burst Peripartum Period Phagocytosis Phagocytosis - immunology Respiratory Burst - immunology Reverse Transcriptase Polymerase Chain Reaction - veterinary RNA - chemistry RNA - genetics
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