Preparation and Characterization of Inclusion Complexes of a Hemisuccinate Ester Prodrug of Delta D9-Tetrahydrocannabinol with Modified Beta-Cyclodextrins

Delta *D9-Tetrahydrocannabinol hemisuccinate (THC-HS), an ester prodrug of Delta *D9-tetrahydrocannabinol (THC) has been investigated for its potential to form inclusion complexes with modified synthetic beta-cyclodextrins (CDs). Phase solubility studies were performed to determine the stoichiometri...

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Veröffentlicht in:	AAPS PharmSciTech 2010-06, Vol.11 (2), p.509-517
Hauptverfasser:	Upadhye, Sampada B, Kulkarni, Swapnil J, Majumdar, Soumyajit, Avery, Mitchell A, Gul, Waseem, Elsohly, Mahmoud A, Repka, Michael A
Format:	Artikel
Sprache:	eng
Schlagworte:	Indexing in process
Online-Zugang:	Volltext
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