Metabolic profile of dystrophic mdx mouse muscles analyzed with in vitro magnetic resonance spectroscopy (MRS)

Abstract Duchenne muscular dystrophy (DMD) is a recessive X-linked form of muscular dystrophy characterized by progressive and irreversible degeneration of the muscles. The mdx mouse is the classical animal model for DMD, showing similar molecular and protein defects. The mdx mouse, however, does no...

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Veröffentlicht in:	Magnetic resonance imaging 2012-10, Vol.30 (8), p.1167-1176
Hauptverfasser:	Martins-Bach, Aurea B, Bloise, Antonio C, Vainzof, Mariz, Rahnamaye Rabbani, Said
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers - metabolism Duchenne muscular dystrophy High-resolution 1H MRS Indexing in process Magnetic Resonance Spectroscopy - methods mdx Metabolomics Mice Mice, Inbred C57BL Mice, Inbred mdx Muscle Proteins - metabolism Muscle, Skeletal - metabolism Muscular Dystrophy, Duchenne - metabolism Radiology
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