A multi-center, double-blind, randomized, parallel group study to evaluate the effects of two different doses of losartan on morbidity and mortality in Chinese patients with symptomatic heart failure intolerant of angiotensin converting enzyme inhibitor treatment

Background There have been no mortality/morbidity endpoint studies with Iosartan in Chinese heart failure patients. The objective was to evaluate the effects of high-dose vs. low-dose Iosartan on clinical outcomes in Chinese subjects with heart failure.

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Veröffentlicht in:Chinese medical journal 2012-11, Vol.125 (21), p.3868-3874
Hauptverfasser: Hu, Da-Yi, Huang, Jun, Cai, Nai-Sheng, Zhu, Wen-Ling, Li, Yi-Shi, Massaad, Rachid, Hanson, Mary E, Dickstein, Kenneth
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container_end_page 3874
container_issue 21
container_start_page 3868
container_title Chinese medical journal
container_volume 125
creator Hu, Da-Yi
Huang, Jun
Cai, Nai-Sheng
Zhu, Wen-Ling
Li, Yi-Shi
Massaad, Rachid
Hanson, Mary E
Dickstein, Kenneth
description Background There have been no mortality/morbidity endpoint studies with Iosartan in Chinese heart failure patients. The objective was to evaluate the effects of high-dose vs. low-dose Iosartan on clinical outcomes in Chinese subjects with heart failure.
doi_str_mv 10.3760/cma.j.issn.0366-6999.2012.21.023
format Article
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source MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Angiotensin II Type 1 Receptor Blockers - therapeutic use
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
Double-Blind Method
Female
Heart Failure - drug therapy
Humans
Losartan - adverse effects
Losartan - therapeutic use
Male
Middle Aged
中国
低剂量
发病率
心脏
死亡率
血管紧张素转换酶抑制剂
衰竭
评估
title A multi-center, double-blind, randomized, parallel group study to evaluate the effects of two different doses of losartan on morbidity and mortality in Chinese patients with symptomatic heart failure intolerant of angiotensin converting enzyme inhibitor treatment
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