Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey
► Chemical and physical characteristics of the polysaccharides were investigated. ► Antioxidant and hepatoprotective effects of the polysaccharides were investigated. ► The HEP80 showed strong activity on antioxidant and hepatoprotective activities. ► The hepatoprotective effect may be due to its po...
Gespeichert in:
| Veröffentlicht in: | International journal of biological macromolecules 2012-12, Vol.51 (5), p.1140-1146 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1146 |
|---|---|
| container_issue | 5 |
| container_start_page | 1140 |
| container_title | International journal of biological macromolecules |
| container_volume | 51 |
| creator | Zhang, Zuofa Lv, Guoying Pan, Huijuan Pandey, Ashok He, Weiqiang Fan, Leifa |
| description | ► Chemical and physical characteristics of the polysaccharides were investigated. ► Antioxidant and hepatoprotective effects of the polysaccharides were investigated. ► The HEP80 showed strong activity on antioxidant and hepatoprotective activities. ► The hepatoprotective effect may be due to its potent antioxidant capacity.
Three fractions of the endo-polysaccharides from the mycelium of Hericium erinaceus (HEP) grown on tofu whey were obtained by the fractional precipitation with gradient concentrations of ethanol (HEP40, HEP60 and HEP80). The chemical and physical characteristics of the three crude polysaccharides were investigated by the combination of chemical and instrumental analysis methods. The studies to evaluate the antioxidant potential and the hepatoprotective effects of the three polysaccharides showed that they had different activities in different evaluation system. HEP80 showed strong activity on antioxidant in vitro and potent hepatoprotective effect in vivo and the hepatoprotective effect may be due to its potent antioxidant capacity. The HEP could be exploited as antioxidant product and a supplement in the prevention of hepatic diseases. The study also opens an avenue for the efficient utilization of tofu whey, which is usually discarded in environment, causing concerns. |
| doi_str_mv | 10.1016/j.ijbiomac.2012.09.002 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1115531785</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S014181301200356X</els_id><sourcerecordid>1115531785</sourcerecordid><originalsourceid>FETCH-LOGICAL-c434t-461a86bc5790af5f2175fcaab5602360c65acaf223b99714dad8a602e3a4e3ec3</originalsourceid><addsrcrecordid>eNqFkEtv1DAQgK2Kii6Fv1D5yCXBjziPG1VFKVIlLvRsTewx61Vip3bSsv8eV9ty5TSjmW9mNB8hV5zVnPH2y6H2h9HHGUwtGBc1G2rGxBnZ8b4bKsaYfEd2jDe86rlkF-RDzodSbRXv35MLIYZe9JztyHwdVh__eAthpRAs3eMCa1xSXNGs_gnpUrLCwESjoxhsrJY4HTMYs4fkLWbqUpzpHSZv_DbTEgMY3DL9neJzoDHQNbqNPu_x-JGcO5gyfnqNl-Th9tuvm7vq_uf3HzfX95VpZLNWTcuhb0ejuoGBU07wTjkDMKqWCdky0yow4ISQ4zB0vLFgeygtlNCgRCMvyefT3vLH44Z51bPPBqcJAsYta865UpJ3vSpoe0JNijkndHpJfoZ01JzpF9X6oN9U6xfVmg26qC6DV683tnFG-2_szW0Bvp4ALJ8-eUw6G4_BoPWpuNU2-v_d-AtSdZWe</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1115531785</pqid></control><display><type>article</type><title>Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Zhang, Zuofa ; Lv, Guoying ; Pan, Huijuan ; Pandey, Ashok ; He, Weiqiang ; Fan, Leifa</creator><creatorcontrib>Zhang, Zuofa ; Lv, Guoying ; Pan, Huijuan ; Pandey, Ashok ; He, Weiqiang ; Fan, Leifa</creatorcontrib><description>► Chemical and physical characteristics of the polysaccharides were investigated. ► Antioxidant and hepatoprotective effects of the polysaccharides were investigated. ► The HEP80 showed strong activity on antioxidant and hepatoprotective activities. ► The hepatoprotective effect may be due to its potent antioxidant capacity.
Three fractions of the endo-polysaccharides from the mycelium of Hericium erinaceus (HEP) grown on tofu whey were obtained by the fractional precipitation with gradient concentrations of ethanol (HEP40, HEP60 and HEP80). The chemical and physical characteristics of the three crude polysaccharides were investigated by the combination of chemical and instrumental analysis methods. The studies to evaluate the antioxidant potential and the hepatoprotective effects of the three polysaccharides showed that they had different activities in different evaluation system. HEP80 showed strong activity on antioxidant in vitro and potent hepatoprotective effect in vivo and the hepatoprotective effect may be due to its potent antioxidant capacity. The HEP could be exploited as antioxidant product and a supplement in the prevention of hepatic diseases. The study also opens an avenue for the efficient utilization of tofu whey, which is usually discarded in environment, causing concerns.</description><identifier>ISSN: 0141-8130</identifier><identifier>EISSN: 1879-0003</identifier><identifier>DOI: 10.1016/j.ijbiomac.2012.09.002</identifier><identifier>PMID: 22982810</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Animals ; Antioxidant activity ; Basidiomycota - chemistry ; Basidiomycota - growth & development ; Biphenyl Compounds - chemistry ; Catalase - metabolism ; Cytoprotection - drug effects ; Free Radical Scavengers - chemistry ; Free Radical Scavengers - isolation & purification ; Free Radical Scavengers - pharmacology ; Glutathione Peroxidase - metabolism ; Hepatoprotective effect ; Hericium erinaceus ; Iron Chelating Agents - chemistry ; Iron Chelating Agents - isolation & purification ; Iron Chelating Agents - pharmacology ; Liver - cytology ; Liver - drug effects ; Liver - metabolism ; Male ; Malondialdehyde - metabolism ; Mice ; Mice, Inbred ICR ; Oxidation-Reduction ; Picrates - chemistry ; Polysaccharides ; Polysaccharides - chemistry ; Polysaccharides - isolation & purification ; Polysaccharides - pharmacology ; Soy Foods ; Superoxide Dismutase - metabolism ; Tofu whey</subject><ispartof>International journal of biological macromolecules, 2012-12, Vol.51 (5), p.1140-1146</ispartof><rights>2012 Elsevier B.V.</rights><rights>Copyright © 2012 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c434t-461a86bc5790af5f2175fcaab5602360c65acaf223b99714dad8a602e3a4e3ec3</citedby><cites>FETCH-LOGICAL-c434t-461a86bc5790af5f2175fcaab5602360c65acaf223b99714dad8a602e3a4e3ec3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S014181301200356X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22982810$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Zuofa</creatorcontrib><creatorcontrib>Lv, Guoying</creatorcontrib><creatorcontrib>Pan, Huijuan</creatorcontrib><creatorcontrib>Pandey, Ashok</creatorcontrib><creatorcontrib>He, Weiqiang</creatorcontrib><creatorcontrib>Fan, Leifa</creatorcontrib><title>Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey</title><title>International journal of biological macromolecules</title><addtitle>Int J Biol Macromol</addtitle><description>► Chemical and physical characteristics of the polysaccharides were investigated. ► Antioxidant and hepatoprotective effects of the polysaccharides were investigated. ► The HEP80 showed strong activity on antioxidant and hepatoprotective activities. ► The hepatoprotective effect may be due to its potent antioxidant capacity.
Three fractions of the endo-polysaccharides from the mycelium of Hericium erinaceus (HEP) grown on tofu whey were obtained by the fractional precipitation with gradient concentrations of ethanol (HEP40, HEP60 and HEP80). The chemical and physical characteristics of the three crude polysaccharides were investigated by the combination of chemical and instrumental analysis methods. The studies to evaluate the antioxidant potential and the hepatoprotective effects of the three polysaccharides showed that they had different activities in different evaluation system. HEP80 showed strong activity on antioxidant in vitro and potent hepatoprotective effect in vivo and the hepatoprotective effect may be due to its potent antioxidant capacity. The HEP could be exploited as antioxidant product and a supplement in the prevention of hepatic diseases. The study also opens an avenue for the efficient utilization of tofu whey, which is usually discarded in environment, causing concerns.</description><subject>Animals</subject><subject>Antioxidant activity</subject><subject>Basidiomycota - chemistry</subject><subject>Basidiomycota - growth & development</subject><subject>Biphenyl Compounds - chemistry</subject><subject>Catalase - metabolism</subject><subject>Cytoprotection - drug effects</subject><subject>Free Radical Scavengers - chemistry</subject><subject>Free Radical Scavengers - isolation & purification</subject><subject>Free Radical Scavengers - pharmacology</subject><subject>Glutathione Peroxidase - metabolism</subject><subject>Hepatoprotective effect</subject><subject>Hericium erinaceus</subject><subject>Iron Chelating Agents - chemistry</subject><subject>Iron Chelating Agents - isolation & purification</subject><subject>Iron Chelating Agents - pharmacology</subject><subject>Liver - cytology</subject><subject>Liver - drug effects</subject><subject>Liver - metabolism</subject><subject>Male</subject><subject>Malondialdehyde - metabolism</subject><subject>Mice</subject><subject>Mice, Inbred ICR</subject><subject>Oxidation-Reduction</subject><subject>Picrates - chemistry</subject><subject>Polysaccharides</subject><subject>Polysaccharides - chemistry</subject><subject>Polysaccharides - isolation & purification</subject><subject>Polysaccharides - pharmacology</subject><subject>Soy Foods</subject><subject>Superoxide Dismutase - metabolism</subject><subject>Tofu whey</subject><issn>0141-8130</issn><issn>1879-0003</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtv1DAQgK2Kii6Fv1D5yCXBjziPG1VFKVIlLvRsTewx61Vip3bSsv8eV9ty5TSjmW9mNB8hV5zVnPH2y6H2h9HHGUwtGBc1G2rGxBnZ8b4bKsaYfEd2jDe86rlkF-RDzodSbRXv35MLIYZe9JztyHwdVh__eAthpRAs3eMCa1xSXNGs_gnpUrLCwESjoxhsrJY4HTMYs4fkLWbqUpzpHSZv_DbTEgMY3DL9neJzoDHQNbqNPu_x-JGcO5gyfnqNl-Th9tuvm7vq_uf3HzfX95VpZLNWTcuhb0ejuoGBU07wTjkDMKqWCdky0yow4ISQ4zB0vLFgeygtlNCgRCMvyefT3vLH44Z51bPPBqcJAsYta865UpJ3vSpoe0JNijkndHpJfoZ01JzpF9X6oN9U6xfVmg26qC6DV683tnFG-2_szW0Bvp4ALJ8-eUw6G4_BoPWpuNU2-v_d-AtSdZWe</recordid><startdate>201212</startdate><enddate>201212</enddate><creator>Zhang, Zuofa</creator><creator>Lv, Guoying</creator><creator>Pan, Huijuan</creator><creator>Pandey, Ashok</creator><creator>He, Weiqiang</creator><creator>Fan, Leifa</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201212</creationdate><title>Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey</title><author>Zhang, Zuofa ; Lv, Guoying ; Pan, Huijuan ; Pandey, Ashok ; He, Weiqiang ; Fan, Leifa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c434t-461a86bc5790af5f2175fcaab5602360c65acaf223b99714dad8a602e3a4e3ec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Animals</topic><topic>Antioxidant activity</topic><topic>Basidiomycota - chemistry</topic><topic>Basidiomycota - growth & development</topic><topic>Biphenyl Compounds - chemistry</topic><topic>Catalase - metabolism</topic><topic>Cytoprotection - drug effects</topic><topic>Free Radical Scavengers - chemistry</topic><topic>Free Radical Scavengers - isolation & purification</topic><topic>Free Radical Scavengers - pharmacology</topic><topic>Glutathione Peroxidase - metabolism</topic><topic>Hepatoprotective effect</topic><topic>Hericium erinaceus</topic><topic>Iron Chelating Agents - chemistry</topic><topic>Iron Chelating Agents - isolation & purification</topic><topic>Iron Chelating Agents - pharmacology</topic><topic>Liver - cytology</topic><topic>Liver - drug effects</topic><topic>Liver - metabolism</topic><topic>Male</topic><topic>Malondialdehyde - metabolism</topic><topic>Mice</topic><topic>Mice, Inbred ICR</topic><topic>Oxidation-Reduction</topic><topic>Picrates - chemistry</topic><topic>Polysaccharides</topic><topic>Polysaccharides - chemistry</topic><topic>Polysaccharides - isolation & purification</topic><topic>Polysaccharides - pharmacology</topic><topic>Soy Foods</topic><topic>Superoxide Dismutase - metabolism</topic><topic>Tofu whey</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Zuofa</creatorcontrib><creatorcontrib>Lv, Guoying</creatorcontrib><creatorcontrib>Pan, Huijuan</creatorcontrib><creatorcontrib>Pandey, Ashok</creatorcontrib><creatorcontrib>He, Weiqiang</creatorcontrib><creatorcontrib>Fan, Leifa</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of biological macromolecules</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Zuofa</au><au>Lv, Guoying</au><au>Pan, Huijuan</au><au>Pandey, Ashok</au><au>He, Weiqiang</au><au>Fan, Leifa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey</atitle><jtitle>International journal of biological macromolecules</jtitle><addtitle>Int J Biol Macromol</addtitle><date>2012-12</date><risdate>2012</risdate><volume>51</volume><issue>5</issue><spage>1140</spage><epage>1146</epage><pages>1140-1146</pages><issn>0141-8130</issn><eissn>1879-0003</eissn><abstract>► Chemical and physical characteristics of the polysaccharides were investigated. ► Antioxidant and hepatoprotective effects of the polysaccharides were investigated. ► The HEP80 showed strong activity on antioxidant and hepatoprotective activities. ► The hepatoprotective effect may be due to its potent antioxidant capacity.
Three fractions of the endo-polysaccharides from the mycelium of Hericium erinaceus (HEP) grown on tofu whey were obtained by the fractional precipitation with gradient concentrations of ethanol (HEP40, HEP60 and HEP80). The chemical and physical characteristics of the three crude polysaccharides were investigated by the combination of chemical and instrumental analysis methods. The studies to evaluate the antioxidant potential and the hepatoprotective effects of the three polysaccharides showed that they had different activities in different evaluation system. HEP80 showed strong activity on antioxidant in vitro and potent hepatoprotective effect in vivo and the hepatoprotective effect may be due to its potent antioxidant capacity. The HEP could be exploited as antioxidant product and a supplement in the prevention of hepatic diseases. The study also opens an avenue for the efficient utilization of tofu whey, which is usually discarded in environment, causing concerns.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>22982810</pmid><doi>10.1016/j.ijbiomac.2012.09.002</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0141-8130 |
| ispartof | International journal of biological macromolecules, 2012-12, Vol.51 (5), p.1140-1146 |
| issn | 0141-8130 1879-0003 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1115531785 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Antioxidant activity Basidiomycota - chemistry Basidiomycota - growth & development Biphenyl Compounds - chemistry Catalase - metabolism Cytoprotection - drug effects Free Radical Scavengers - chemistry Free Radical Scavengers - isolation & purification Free Radical Scavengers - pharmacology Glutathione Peroxidase - metabolism Hepatoprotective effect Hericium erinaceus Iron Chelating Agents - chemistry Iron Chelating Agents - isolation & purification Iron Chelating Agents - pharmacology Liver - cytology Liver - drug effects Liver - metabolism Male Malondialdehyde - metabolism Mice Mice, Inbred ICR Oxidation-Reduction Picrates - chemistry Polysaccharides Polysaccharides - chemistry Polysaccharides - isolation & purification Polysaccharides - pharmacology Soy Foods Superoxide Dismutase - metabolism Tofu whey |
| title | Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T19%3A13%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Antioxidant%20and%20hepatoprotective%20potential%20of%20endo-polysaccharides%20from%20Hericium%20erinaceus%20grown%20on%20tofu%20whey&rft.jtitle=International%20journal%20of%20biological%20macromolecules&rft.au=Zhang,%20Zuofa&rft.date=2012-12&rft.volume=51&rft.issue=5&rft.spage=1140&rft.epage=1146&rft.pages=1140-1146&rft.issn=0141-8130&rft.eissn=1879-0003&rft_id=info:doi/10.1016/j.ijbiomac.2012.09.002&rft_dat=%3Cproquest_cross%3E1115531785%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1115531785&rft_id=info:pmid/22982810&rft_els_id=S014181301200356X&rfr_iscdi=true |