Sperm-specific glyceraldehyde-3-phosphate dehydrogenase is expressed in melanoma cells

► Melanoma cells were assayed for expression of sperm-specific glycolytic enzyme GAPDS. ► GAPDS fragment lacking N-terminal amino acid sequence is revealed in melanoma cells. ► The revealed GAPDS species form hybrid tetramers with somatic isoenzyme GAPD. ► Immunochemical staining of melanoma cells r...

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Veröffentlicht in:	Biochemical and biophysical research communications 2012-10, Vol.427 (3), p.649-653
Hauptverfasser:	Sevostyanova, Irina A., Kulikova, Kseniya V., Kuravsky, Mikhail L., Schmalhausen, Elena V., Muronetz, Vladimir I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene Expression Regulation, Enzymologic Gene Expression Regulation, Neoplastic Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) - genetics HEK293 Cells HL-60 Cells Humans Jurkat Cells Male Melanoma Melanoma - enzymology RNA, Messenger - genetics Sperm-specific glyceraldehyde-3-phosphate dehydrogenase Spermatozoa - enzymology Сancer/testis associated genes
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