Interleukin 7 (IL-7) selectively promotes mouse and human IL-17–producing γδ cells

IL-17–producing CD27 ⁻ γδ cells (γδ ²⁷⁻ cells) are widely viewed as innate immune cells that make critical contributions to host protection and autoimmunity. However, factors that promote them over IFN-γ–producing γδ ²⁷⁺ cells are poorly elucidated. Moreover, although human IL-17–producing γδ cells...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2012-10, Vol.109 (43), p.17549-17554
Hauptverfasser: Michel, Marie-Laure, Pang, Dick J, Haque, Syeda F. Y, Potocnik, Alexandre J, Pennington, Daniel J, Hayday, Adrian C
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Sprache:eng
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