Immunophenotypic Identification and Characterization of Tumor Cells and Infiltrating Cell Populations in Meningiomas

Meningiomas are primary tumors of the central nervous system composed of both neoplastic and other infiltrating cells. We determined the cellular composition of 51 meningioma samples by multiparameter flow cytometric (MFC) immunophenotyping and investigated the potential relationship between mRNA an...

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Veröffentlicht in:	The American journal of pathology 2012-11, Vol.181 (5), p.1749-1761
Hauptverfasser:	Domingues, Patrícia H, Teodósio, Cristina, Ortiz, Javier, Sousa, Pablo, Otero, Álvaro, Maillo, Angel, Bárcena, Paloma, García-Macias, Maria C, Lopes, Maria C, de Oliveira, Catarina, Orfao, Alberto, Tabernero, Maria D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Cell Compartmentation Female Flow Cytometry Gene Expression Profiling Gene Expression Regulation, Neoplastic Humans Immunophenotyping Investigative techniques, diagnostic techniques (general aspects) Lymphocytes, Tumor-Infiltrating - immunology Lymphocytes, Tumor-Infiltrating - metabolism Lymphocytes, Tumor-Infiltrating - pathology Male Medical sciences Meningeal Neoplasms - genetics Meningeal Neoplasms - immunology Meningeal Neoplasms - pathology Meningioma - genetics Meningioma - immunology Meningioma - pathology Middle Aged Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Neurology Pathology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Phagocytosis RNA, Messenger - genetics RNA, Messenger - metabolism Tumors of the nervous system. Phacomatoses
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