Hair growth-promoting effect of Aconiti Ciliare Tuber extract mediated by the activation of Wnt/β-catenin signaling

The activation of Wnt/β-catenin signaling pathway plays an important role in hair follicle morphogenesis by stimulating bulge stem cells. This study was to obtain the activator of Wnt/β-catenin signaling pathway from natural products and to determine whether this activator can induce anagen hair gro...

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Veröffentlicht in:	Life sciences (1973) 2012-11, Vol.91 (19-20), p.935-943
Hauptverfasser:	Park, Phil-June, Moon, Byoung-San, Lee, Soung-Hoon, Kim, Su-Na, Kim, Ah-Reum, Kim, Hyung-Jun, Park, Won-Seok, Choi, Kang-Yell, Cho, Eun-Gyung, Lee, Tae Ryong
Format:	Artikel
Sprache:	eng
Schlagworte:	Aconiti Ciliare Tuber (ACT) extract Aconitum - chemistry Alkaline phosphatase (ALP) Alkaline Phosphatase - metabolism Animals beta Catenin - metabolism Cell Differentiation - drug effects Cell Proliferation - drug effects Dose-Response Relationship, Drug Hair - drug effects Hair - growth & development Hair growth HEK293 Cells Humans Male Mice Mice, Inbred C57BL Plant Extracts - administration & dosage Plant Extracts - pharmacology Rats Rats, Sprague-Dawley Stem Cells - metabolism Transcription, Genetic - drug effects Wnt Signaling Pathway - drug effects Wnt/β-catenin signaling pathway
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