Different antigen presentation tendencies of granulocyte-macrophage colony-stimulating factor-induced bone marrow-derived macrophages and peritoneal macrophages
Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced bone marrow-derived cells (BMCs) and primary peritoneal exudate cells (PECs) are usually used for antigen presentation in in vitro experiments. In order to expound their tendency for uptake and antigen presentation, we compared differ...
Gespeichert in:
| Veröffentlicht in: | In vitro cellular & developmental biology. Animal 2012-08, Vol.48 (7), p.434-440 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 440 |
|---|---|
| container_issue | 7 |
| container_start_page | 434 |
| container_title | In vitro cellular & developmental biology. Animal |
| container_volume | 48 |
| creator | Hu, Maozhi Pan, Zhiming Yang, Yun Meng, Chuang Geng, Shizhong You, Meng Jiao, Xinan |
| description | Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced bone marrow-derived cells (BMCs) and primary peritoneal exudate cells (PECs) are usually used for antigen presentation in in vitro experiments. In order to expound their tendency for uptake and antigen presentation, we compared differences in the degree of phagocytosis, the expression of co-stimulatory molecules, and the activation of T lymphocytes between these two cell types. These assays used the F4/80 marker expression, as it is the general marker for macrophages. The BMC population was found to contain both F4/80bright and F4/80dim subtypes, while PECs were mainly composed of the F4/80bright subtype. Expression levels of cell surface co-stimulatory molecules, CD80, CD86, CD54, and CD40, were significantly higher for F4/80+BMCs than F4/80+PECs. Their expressions were further upregulated for F4/80+BMCs than for F4/80+PECs after stimulation with flagellin. F4/80+BMCs had a weaker ability to phagocytize microbeads than F4/80+PECs (P |
| doi_str_mv | 10.1007/s11626-012-9535-7 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1113230377</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>23279458</jstor_id><sourcerecordid>23279458</sourcerecordid><originalsourceid>FETCH-LOGICAL-c517t-510d5baa248e49b19f9783dc811da4cada09667ef4902f218259377772044ae23</originalsourceid><addsrcrecordid>eNqFUctu1TAQjRCIlsIHsAAssWFj8PiRxEtUnlIlFlCJneWbTEKuEjvYCej-DZ_KXFJoxQK8sT3nMR6fongI4jkIUb3IAKUsuQDJrVGGV7eKUzBa8UqUn2_TWVTAZWnFSXEv572gZaG8W5xIWYvSVuq0-PFq6DpMGBbmwzL0GNicMNPdL0MMbMHQYmgGzCx2rE8-rGNsDgvyyTcpzl98j6yJYwwHnpdhWkfShZ51vlli4kNo1wZbtosB2eRTit95i2n4RrVrg0y9WzZTfSGeH29C94s7nR8zPrjaz4rLN68_nb_jFx_evj9_ecEbA9XCDYjW7LyXukZtd2A7W9WqbWqA1uvGt17Ysqyw01bITkItjVUVLSm09ijVWfFs851T_LpiXtw05AbH0QeMa3YAoKQSpPk_VSiljTHCEvXpX9R9XFOgQRxobX4lcuwNG4umzjlh5-Y00G8dyModk3Zb0o6Sdsek3fERj6-c192E7R_F72iJIDdCJij0mG60_ofro020zxTftamSldWmJvzJhnc-Ot-nIbvLj1KAFgKIIYz6CeLEyWg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1445000092</pqid></control><display><type>article</type><title>Different antigen presentation tendencies of granulocyte-macrophage colony-stimulating factor-induced bone marrow-derived macrophages and peritoneal macrophages</title><source>MEDLINE</source><source>JSTOR Archive Collection A-Z Listing</source><source>SpringerLink Journals - AutoHoldings</source><creator>Hu, Maozhi ; Pan, Zhiming ; Yang, Yun ; Meng, Chuang ; Geng, Shizhong ; You, Meng ; Jiao, Xinan</creator><creatorcontrib>Hu, Maozhi ; Pan, Zhiming ; Yang, Yun ; Meng, Chuang ; Geng, Shizhong ; You, Meng ; Jiao, Xinan</creatorcontrib><description>Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced bone marrow-derived cells (BMCs) and primary peritoneal exudate cells (PECs) are usually used for antigen presentation in in vitro experiments. In order to expound their tendency for uptake and antigen presentation, we compared differences in the degree of phagocytosis, the expression of co-stimulatory molecules, and the activation of T lymphocytes between these two cell types. These assays used the F4/80 marker expression, as it is the general marker for macrophages. The BMC population was found to contain both F4/80bright and F4/80dim subtypes, while PECs were mainly composed of the F4/80bright subtype. Expression levels of cell surface co-stimulatory molecules, CD80, CD86, CD54, and CD40, were significantly higher for F4/80+BMCs than F4/80+PECs. Their expressions were further upregulated for F4/80+BMCs than for F4/80+PECs after stimulation with flagellin. F4/80+BMCs had a weaker ability to phagocytize microbeads than F4/80+PECs (P < 0.05), and we determined no relationship between F4/80 expression and phagocytosis. T lymphocytes were activated more efficiently after incubation with BMCs pulsed with flagellin than with pulsed PECs. In this study, F4/80+BMCs and F4/80+PECs represent the bone marrow-derived macrophages (BMMs) and peritoneal macrophages (PMs), respectively. These results indicate that PMs showed greater potential for phagocytosis, whereas GM-CSF-induced BMMs showed a tendency toward antigen presentation.</description><identifier>ISSN: 1071-2690</identifier><identifier>EISSN: 1543-706X</identifier><identifier>DOI: 10.1007/s11626-012-9535-7</identifier><identifier>PMID: 22806973</identifier><identifier>CODEN: IVCAED</identifier><language>eng</language><publisher>New York: Springer-Verlag</publisher><subject>Animal Genetics and Genomics ; Antigen presentation ; Antigen Presentation - immunology ; Antigens ; Antigens, Differentiation - metabolism ; Biomedical and Life Sciences ; Bone marrow ; Bone mineral content ; Bones ; CD40 antigen ; CD80 antigen ; CD86 antigen ; Cell activation ; CELL AND TISSUE MODELS ; Cell Biology ; Cell Culture ; Cell surface ; Cytometry ; Developmental Biology ; Flagellin ; Flow Cytometry ; Granulocyte-macrophage colony-stimulating factor ; Granulocyte-Macrophage Colony-Stimulating Factor - metabolism ; in vitro studies ; Life Sciences ; Lymphocyte Activation - immunology ; Lymphocytes T ; Macrophages ; Macrophages - immunology ; Macrophages - metabolism ; Macrophages, Peritoneal - immunology ; Microspheres ; Molecules ; Peritoneal exudate cells ; Peritoneal macrophages ; Peritoneum ; Phagocytosis ; Phagocytosis - immunology ; Splenocytes ; Stem Cells ; T lymphocytes ; T-Lymphocytes - immunology</subject><ispartof>In vitro cellular & developmental biology. Animal, 2012-08, Vol.48 (7), p.434-440</ispartof><rights>The Society for In Vitro Biology 2012</rights><rights>Copyright Society for In Vitro Biology Aug 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c517t-510d5baa248e49b19f9783dc811da4cada09667ef4902f218259377772044ae23</citedby><cites>FETCH-LOGICAL-c517t-510d5baa248e49b19f9783dc811da4cada09667ef4902f218259377772044ae23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/23279458$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/23279458$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,27924,27925,41488,42557,51319,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22806973$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hu, Maozhi</creatorcontrib><creatorcontrib>Pan, Zhiming</creatorcontrib><creatorcontrib>Yang, Yun</creatorcontrib><creatorcontrib>Meng, Chuang</creatorcontrib><creatorcontrib>Geng, Shizhong</creatorcontrib><creatorcontrib>You, Meng</creatorcontrib><creatorcontrib>Jiao, Xinan</creatorcontrib><title>Different antigen presentation tendencies of granulocyte-macrophage colony-stimulating factor-induced bone marrow-derived macrophages and peritoneal macrophages</title><title>In vitro cellular & developmental biology. Animal</title><addtitle>In Vitro Cell.Dev.Biol.-Animal</addtitle><addtitle>In Vitro Cell Dev Biol Anim</addtitle><description>Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced bone marrow-derived cells (BMCs) and primary peritoneal exudate cells (PECs) are usually used for antigen presentation in in vitro experiments. In order to expound their tendency for uptake and antigen presentation, we compared differences in the degree of phagocytosis, the expression of co-stimulatory molecules, and the activation of T lymphocytes between these two cell types. These assays used the F4/80 marker expression, as it is the general marker for macrophages. The BMC population was found to contain both F4/80bright and F4/80dim subtypes, while PECs were mainly composed of the F4/80bright subtype. Expression levels of cell surface co-stimulatory molecules, CD80, CD86, CD54, and CD40, were significantly higher for F4/80+BMCs than F4/80+PECs. Their expressions were further upregulated for F4/80+BMCs than for F4/80+PECs after stimulation with flagellin. F4/80+BMCs had a weaker ability to phagocytize microbeads than F4/80+PECs (P < 0.05), and we determined no relationship between F4/80 expression and phagocytosis. T lymphocytes were activated more efficiently after incubation with BMCs pulsed with flagellin than with pulsed PECs. In this study, F4/80+BMCs and F4/80+PECs represent the bone marrow-derived macrophages (BMMs) and peritoneal macrophages (PMs), respectively. These results indicate that PMs showed greater potential for phagocytosis, whereas GM-CSF-induced BMMs showed a tendency toward antigen presentation.</description><subject>Animal Genetics and Genomics</subject><subject>Antigen presentation</subject><subject>Antigen Presentation - immunology</subject><subject>Antigens</subject><subject>Antigens, Differentiation - metabolism</subject><subject>Biomedical and Life Sciences</subject><subject>Bone marrow</subject><subject>Bone mineral content</subject><subject>Bones</subject><subject>CD40 antigen</subject><subject>CD80 antigen</subject><subject>CD86 antigen</subject><subject>Cell activation</subject><subject>CELL AND TISSUE MODELS</subject><subject>Cell Biology</subject><subject>Cell Culture</subject><subject>Cell surface</subject><subject>Cytometry</subject><subject>Developmental Biology</subject><subject>Flagellin</subject><subject>Flow Cytometry</subject><subject>Granulocyte-macrophage colony-stimulating factor</subject><subject>Granulocyte-Macrophage Colony-Stimulating Factor - metabolism</subject><subject>in vitro studies</subject><subject>Life Sciences</subject><subject>Lymphocyte Activation - immunology</subject><subject>Lymphocytes T</subject><subject>Macrophages</subject><subject>Macrophages - immunology</subject><subject>Macrophages - metabolism</subject><subject>Macrophages, Peritoneal - immunology</subject><subject>Microspheres</subject><subject>Molecules</subject><subject>Peritoneal exudate cells</subject><subject>Peritoneal macrophages</subject><subject>Peritoneum</subject><subject>Phagocytosis</subject><subject>Phagocytosis - immunology</subject><subject>Splenocytes</subject><subject>Stem Cells</subject><subject>T lymphocytes</subject><subject>T-Lymphocytes - immunology</subject><issn>1071-2690</issn><issn>1543-706X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFUctu1TAQjRCIlsIHsAAssWFj8PiRxEtUnlIlFlCJneWbTEKuEjvYCej-DZ_KXFJoxQK8sT3nMR6fongI4jkIUb3IAKUsuQDJrVGGV7eKUzBa8UqUn2_TWVTAZWnFSXEv572gZaG8W5xIWYvSVuq0-PFq6DpMGBbmwzL0GNicMNPdL0MMbMHQYmgGzCx2rE8-rGNsDgvyyTcpzl98j6yJYwwHnpdhWkfShZ51vlli4kNo1wZbtosB2eRTit95i2n4RrVrg0y9WzZTfSGeH29C94s7nR8zPrjaz4rLN68_nb_jFx_evj9_ecEbA9XCDYjW7LyXukZtd2A7W9WqbWqA1uvGt17Ysqyw01bITkItjVUVLSm09ijVWfFs851T_LpiXtw05AbH0QeMa3YAoKQSpPk_VSiljTHCEvXpX9R9XFOgQRxobX4lcuwNG4umzjlh5-Y00G8dyModk3Zb0o6Sdsek3fERj6-c192E7R_F72iJIDdCJij0mG60_ofro020zxTftamSldWmJvzJhnc-Ot-nIbvLj1KAFgKIIYz6CeLEyWg</recordid><startdate>20120801</startdate><enddate>20120801</enddate><creator>Hu, Maozhi</creator><creator>Pan, Zhiming</creator><creator>Yang, Yun</creator><creator>Meng, Chuang</creator><creator>Geng, Shizhong</creator><creator>You, Meng</creator><creator>Jiao, Xinan</creator><general>Springer-Verlag</general><general>Springer Science + Business Media</general><general>Society for In Vitro Biology</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>4T-</scope><scope>7QL</scope><scope>7T7</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope><scope>7QO</scope></search><sort><creationdate>20120801</creationdate><title>Different antigen presentation tendencies of granulocyte-macrophage colony-stimulating factor-induced bone marrow-derived macrophages and peritoneal macrophages</title><author>Hu, Maozhi ; Pan, Zhiming ; Yang, Yun ; Meng, Chuang ; Geng, Shizhong ; You, Meng ; Jiao, Xinan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c517t-510d5baa248e49b19f9783dc811da4cada09667ef4902f218259377772044ae23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Animal Genetics and Genomics</topic><topic>Antigen presentation</topic><topic>Antigen Presentation - immunology</topic><topic>Antigens</topic><topic>Antigens, Differentiation - metabolism</topic><topic>Biomedical and Life Sciences</topic><topic>Bone marrow</topic><topic>Bone mineral content</topic><topic>Bones</topic><topic>CD40 antigen</topic><topic>CD80 antigen</topic><topic>CD86 antigen</topic><topic>Cell activation</topic><topic>CELL AND TISSUE MODELS</topic><topic>Cell Biology</topic><topic>Cell Culture</topic><topic>Cell surface</topic><topic>Cytometry</topic><topic>Developmental Biology</topic><topic>Flagellin</topic><topic>Flow Cytometry</topic><topic>Granulocyte-macrophage colony-stimulating factor</topic><topic>Granulocyte-Macrophage Colony-Stimulating Factor - metabolism</topic><topic>in vitro studies</topic><topic>Life Sciences</topic><topic>Lymphocyte Activation - immunology</topic><topic>Lymphocytes T</topic><topic>Macrophages</topic><topic>Macrophages - immunology</topic><topic>Macrophages - metabolism</topic><topic>Macrophages, Peritoneal - immunology</topic><topic>Microspheres</topic><topic>Molecules</topic><topic>Peritoneal exudate cells</topic><topic>Peritoneal macrophages</topic><topic>Peritoneum</topic><topic>Phagocytosis</topic><topic>Phagocytosis - immunology</topic><topic>Splenocytes</topic><topic>Stem Cells</topic><topic>T lymphocytes</topic><topic>T-Lymphocytes - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hu, Maozhi</creatorcontrib><creatorcontrib>Pan, Zhiming</creatorcontrib><creatorcontrib>Yang, Yun</creatorcontrib><creatorcontrib>Meng, Chuang</creatorcontrib><creatorcontrib>Geng, Shizhong</creatorcontrib><creatorcontrib>You, Meng</creatorcontrib><creatorcontrib>Jiao, Xinan</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><jtitle>In vitro cellular & developmental biology. Animal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hu, Maozhi</au><au>Pan, Zhiming</au><au>Yang, Yun</au><au>Meng, Chuang</au><au>Geng, Shizhong</au><au>You, Meng</au><au>Jiao, Xinan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Different antigen presentation tendencies of granulocyte-macrophage colony-stimulating factor-induced bone marrow-derived macrophages and peritoneal macrophages</atitle><jtitle>In vitro cellular & developmental biology. Animal</jtitle><stitle>In Vitro Cell.Dev.Biol.-Animal</stitle><addtitle>In Vitro Cell Dev Biol Anim</addtitle><date>2012-08-01</date><risdate>2012</risdate><volume>48</volume><issue>7</issue><spage>434</spage><epage>440</epage><pages>434-440</pages><issn>1071-2690</issn><eissn>1543-706X</eissn><coden>IVCAED</coden><abstract>Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced bone marrow-derived cells (BMCs) and primary peritoneal exudate cells (PECs) are usually used for antigen presentation in in vitro experiments. In order to expound their tendency for uptake and antigen presentation, we compared differences in the degree of phagocytosis, the expression of co-stimulatory molecules, and the activation of T lymphocytes between these two cell types. These assays used the F4/80 marker expression, as it is the general marker for macrophages. The BMC population was found to contain both F4/80bright and F4/80dim subtypes, while PECs were mainly composed of the F4/80bright subtype. Expression levels of cell surface co-stimulatory molecules, CD80, CD86, CD54, and CD40, were significantly higher for F4/80+BMCs than F4/80+PECs. Their expressions were further upregulated for F4/80+BMCs than for F4/80+PECs after stimulation with flagellin. F4/80+BMCs had a weaker ability to phagocytize microbeads than F4/80+PECs (P < 0.05), and we determined no relationship between F4/80 expression and phagocytosis. T lymphocytes were activated more efficiently after incubation with BMCs pulsed with flagellin than with pulsed PECs. In this study, F4/80+BMCs and F4/80+PECs represent the bone marrow-derived macrophages (BMMs) and peritoneal macrophages (PMs), respectively. These results indicate that PMs showed greater potential for phagocytosis, whereas GM-CSF-induced BMMs showed a tendency toward antigen presentation.</abstract><cop>New York</cop><pub>Springer-Verlag</pub><pmid>22806973</pmid><doi>10.1007/s11626-012-9535-7</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1071-2690 |
| ispartof | In vitro cellular & developmental biology. Animal, 2012-08, Vol.48 (7), p.434-440 |
| issn | 1071-2690 1543-706X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1113230377 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing; SpringerLink Journals - AutoHoldings |
| subjects | Animal Genetics and Genomics Antigen presentation Antigen Presentation - immunology Antigens Antigens, Differentiation - metabolism Biomedical and Life Sciences Bone marrow Bone mineral content Bones CD40 antigen CD80 antigen CD86 antigen Cell activation CELL AND TISSUE MODELS Cell Biology Cell Culture Cell surface Cytometry Developmental Biology Flagellin Flow Cytometry Granulocyte-macrophage colony-stimulating factor Granulocyte-Macrophage Colony-Stimulating Factor - metabolism in vitro studies Life Sciences Lymphocyte Activation - immunology Lymphocytes T Macrophages Macrophages - immunology Macrophages - metabolism Macrophages, Peritoneal - immunology Microspheres Molecules Peritoneal exudate cells Peritoneal macrophages Peritoneum Phagocytosis Phagocytosis - immunology Splenocytes Stem Cells T lymphocytes T-Lymphocytes - immunology |
| title | Different antigen presentation tendencies of granulocyte-macrophage colony-stimulating factor-induced bone marrow-derived macrophages and peritoneal macrophages |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T13%3A26%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Different%20antigen%20presentation%20tendencies%20of%20granulocyte-macrophage%20colony-stimulating%20factor-induced%20bone%20marrow-derived%20macrophages%20and%20peritoneal%20macrophages&rft.jtitle=In%20vitro%20cellular%20&%20developmental%20biology.%20Animal&rft.au=Hu,%20Maozhi&rft.date=2012-08-01&rft.volume=48&rft.issue=7&rft.spage=434&rft.epage=440&rft.pages=434-440&rft.issn=1071-2690&rft.eissn=1543-706X&rft.coden=IVCAED&rft_id=info:doi/10.1007/s11626-012-9535-7&rft_dat=%3Cjstor_proqu%3E23279458%3C/jstor_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1445000092&rft_id=info:pmid/22806973&rft_jstor_id=23279458&rfr_iscdi=true |