HIV-1 diseases progression associated with loss of Th17 cells in subtype ‘C’ infection

► A loss of Th17 cell subset can be the cause and/or the effect of high viral load. ► IL-17 producing CD4 T cells may help in distinguishing progressive and nonprogressive HIV infection. ► HIV-1 infection not only leads to functional impairment of Th17 cells but also disturbs amplification setup of...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2012-10, Vol.60 (1), p.55-63
Hauptverfasser:	Singh, Alpana, Vajpayee, Madhu, Ali, Sharique A., Mojumdar, Kamalika, Chauhan, Neeraj Kumar, Singh, Ravinder
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult CD4 antigen CD4 Lymphocyte Count CD4-positive T-lymphocytes CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism Cytokines disease course Disease Progression Female gag Gene Products, Human Immunodeficiency Virus - immunology gastrointestinal system Helper cells HIV infections HIV Infections - immunology HIV Infections - metabolism HIV Infections - virology HIV-1 HIV-1 - classification HIV-1 - immunology HIV-1 - physiology Host-Pathogen Interactions - immunology Human immunodeficiency virus 1 Humans IL-17 IL-21 Immune response Infection Interleukin 17 Interleukin 21 Interleukin-17 - immunology Interleukin-17 - metabolism Interleukins - immunology Interleukins - metabolism Lymphocytes T Male Plasma viral load Th17 cells Th17 Cells - immunology Th17 Cells - metabolism Time Factors viral load Viral Load - immunology viruses
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