Elevated preoperative serum asymmetrical dimethylarginine (ADMA) is associated with poor outcomes after pediatric cardiac surgery

Purpose Asymmetrical dimethylarginine (ADMA), an endogenous competitive inhibitor of nitric oxide synthase, is elevated in vascular pathologies such as hypertension and chronic kidney disease. Children undergoing cardiac surgery are at high risk of poor hemodynamic and renal outcomes secondary to ca...

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Veröffentlicht in:	Intensive care medicine 2012-10, Vol.38 (10), p.1697-1704
Hauptverfasser:	Hassinger, Amanda B., Wainwright, Mark S., Lane, Jerome C., Haymond, Shannon, Backer, Carl L., Wald, Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - blood Acute Kidney Injury - etiology Adolescent Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthesiology Arginine - analogs & derivatives Arginine - blood Biological and medical sciences Cardiac Output, Low - blood Cardiac Output, Low - etiology Cardiopulmonary Bypass - adverse effects Cardiovascular disease Child Child, Preschool Clinical outcomes Congenital diseases Creatinine Critical Care Medicine Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care Emergency Medicine Female Filtration Heart surgery Hemodynamics Hospitals Humans Hypertension Infant Infant, Newborn Intensive Intensive care Intensive care medicine Intensive Care Units, Pediatric Kidney Kidney diseases Length of Stay Male Medical sciences Medicine Medicine & Public Health Mortality Nitric oxide Pain Medicine Pathology Pediatric Original Pediatrics Pneumology/Respiratory System Postoperative Complications - blood Postoperative Complications - etiology Preoperative Period Prospective Studies Respiration, Artificial Risk Factors Surgery Thoracic surgery Treatment Outcome Ventilation Ventilators
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