P014 Ebola virus induces a differential cytokine response and NFKB activation in infected cells

Zaire ebolavirus (EBOV) causes a hemorrhagic disease in humans with case fatality rates up to 90%. A hallmark of EBOV infection is a dysregulated immune response. Macrophages and dendritic cells not only orchestrate innate and adaptive immune responses but are also early target cells of EBOV. Using...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2012-09, Vol.59 (3), p.523-523
Hauptverfasser:	Olejnik, J., Marzi, A., Feldmann, H., Mühlberger, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cell activation Chemokines Cytokines Data processing Dendritic cells Ebola virus eIF-2 kinase Gene expression Hemorrhagic disease Immunofluorescence Infection Inflammation Interleukin 10 Interleukin 6 Lipopolysaccharides Macrophages NF- Kappa B protein Nuclear transport protein kinase R Signal transduction Translocation Vaccines Vero cells Vesicular stomatitis virus Western blotting
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