Dabigatran and left atrial appendage thrombus
A 59-year-old white woman with previous history of arterial hypertension consulted because of palpitations. Atrial fibrillation of uncertain duration was diagnosed. She was not receiving anticoagulants. A trans-esophageal echocardiogram was performed, and a large left atrial appendage thrombus was d...
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| Veröffentlicht in: | Journal of thrombosis and thrombolysis 2012-11, Vol.34 (4), p.545-547 |
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| container_title | Journal of thrombosis and thrombolysis |
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| creator | Vidal, Alejandro Vanerio, Gabriel |
| description | A 59-year-old white woman with previous history of arterial hypertension consulted because of palpitations. Atrial fibrillation of uncertain duration was diagnosed. She was not receiving anticoagulants. A trans-esophageal echocardiogram was performed, and a large left atrial appendage thrombus was detected. A strategy of rate control and anti-vitamin K treatment was started. On the subsequent days, we could not reach therapeutic INRs. Therefore, it was decided to stop warfarin and initiate dabigatran. We describe the evolution of the patient, the thrombus resolution, and a successful electrical cardioversion. In our comments, we summarize the natural history of left atrial thrombus, both with and without anticoagulant therapy. We also discuss the differences between warfarin and dabigatran. |
| doi_str_mv | 10.1007/s11239-012-0747-1 |
| format | Article |
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Atrial fibrillation of uncertain duration was diagnosed. She was not receiving anticoagulants. A trans-esophageal echocardiogram was performed, and a large left atrial appendage thrombus was detected. A strategy of rate control and anti-vitamin K treatment was started. On the subsequent days, we could not reach therapeutic INRs. Therefore, it was decided to stop warfarin and initiate dabigatran. We describe the evolution of the patient, the thrombus resolution, and a successful electrical cardioversion. In our comments, we summarize the natural history of left atrial thrombus, both with and without anticoagulant therapy. 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Vanerio, Gabriel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-c0f2864f2c8b44f46f4a396163667f1df213da904e93f73e0045950e64793d8c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Antithrombins - administration & dosage</topic><topic>Atrial Appendage</topic><topic>Benzimidazoles - administration & dosage</topic><topic>beta-Alanine - administration & dosage</topic><topic>beta-Alanine - analogs & derivatives</topic><topic>Cardiology</topic><topic>Dabigatran</topic><topic>Female</topic><topic>Heart Diseases - drug therapy</topic><topic>Heart Diseases - pathology</topic><topic>Hematology</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Thrombosis - drug therapy</topic><topic>Thrombosis - pathology</topic><topic>Warfarin - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vidal, Alejandro</creatorcontrib><creatorcontrib>Vanerio, Gabriel</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of thrombosis and thrombolysis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vidal, Alejandro</au><au>Vanerio, Gabriel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dabigatran and left atrial appendage thrombus</atitle><jtitle>Journal of thrombosis and thrombolysis</jtitle><stitle>J Thromb Thrombolysis</stitle><addtitle>J Thromb Thrombolysis</addtitle><date>2012-11-01</date><risdate>2012</risdate><volume>34</volume><issue>4</issue><spage>545</spage><epage>547</epage><pages>545-547</pages><issn>0929-5305</issn><eissn>1573-742X</eissn><abstract>A 59-year-old white woman with previous history of arterial hypertension consulted because of palpitations. Atrial fibrillation of uncertain duration was diagnosed. She was not receiving anticoagulants. A trans-esophageal echocardiogram was performed, and a large left atrial appendage thrombus was detected. A strategy of rate control and anti-vitamin K treatment was started. On the subsequent days, we could not reach therapeutic INRs. Therefore, it was decided to stop warfarin and initiate dabigatran. We describe the evolution of the patient, the thrombus resolution, and a successful electrical cardioversion. In our comments, we summarize the natural history of left atrial thrombus, both with and without anticoagulant therapy. We also discuss the differences between warfarin and dabigatran.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>22644719</pmid><doi>10.1007/s11239-012-0747-1</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Journal of thrombosis and thrombolysis, 2012-11, Vol.34 (4), p.545-547 |
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| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Antithrombins - administration & dosage Atrial Appendage Benzimidazoles - administration & dosage beta-Alanine - administration & dosage beta-Alanine - analogs & derivatives Cardiology Dabigatran Female Heart Diseases - drug therapy Heart Diseases - pathology Hematology Humans Medicine Medicine & Public Health Middle Aged Thrombosis - drug therapy Thrombosis - pathology Warfarin - therapeutic use |
| title | Dabigatran and left atrial appendage thrombus |
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