Effect of Alendronate on HIV-Associated Osteoporosis: A Randomized, Double-Blind, Placebo-Controlled, 96-Week Trial (ANRS 120)

Low bone mineral density (BMD) is common in HIV-infected patients. Bisphosphonates such as alendronate potently inhibit bone resorption and are effective against osteoporosis. The aim of the ANRS 120 Fosivir trial was to evaluate the effect of alendronate on low BMD in HIV-infected patients. HIV-1-i...

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Veröffentlicht in:	AIDS research and human retroviruses 2012-09, Vol.28 (9), p.772-780
Hauptverfasser:	ROZENBERG, Sylvie, LANOY, Emillie, BENTATA, Michelle, VIARD, Jean-Paul, VALANTIN, Marc Antoine, MISSY, Pascale, DARASTEANU, Luliana, ROUX, Christian, KOLTA, Sami, COSTAGLIOLA, Dominique
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorptiometry, Photon Acquired Immunodeficiency Syndrome - complications Acquired Immunodeficiency Syndrome - drug therapy Adult Age AIDS/HIV Alendronate - pharmacology Alendronate - therapeutic use Alendronic acid Anti-HIV Agents - therapeutic use antiretroviral therapy Biological and medical sciences Bisphosphonates Bone Density - drug effects Bone Density Conservation Agents - pharmacology Bone Density Conservation Agents - therapeutic use Bone mineral density Bone resorption Calcium carbonate CD4 antigen CD4 Lymphocyte Count Clinical trials Double-Blind Method Dual energy X-ray absorptiometry Female France Fundamental and applied biological sciences. Psychology Hip Hip - diagnostic imaging Human immunodeficiency virus Human viral diseases Humans Infectious diseases Lumbar Vertebrae - diagnostic imaging Male Medical sciences Microbiology Middle Aged Miscellaneous Osteoporosis Osteoporosis - diagnostic imaging Osteoporosis - drug therapy Osteoporosis - etiology Retrovirus Risk factors Spine (lumbar) Treatment Outcome Viral diseases Viral Load Virology Vitamin D
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