Association of aberrations in one-carbon metabolism with molecular phenotype and grade of breast cancer

We have earlier demonstrated the role of aberrant one‐carbon metabolism in the etiology of breast cancer. In the current study, we examine the clinical utility of these factors in predicting the subtype of breast cancer and as indicators of disease progression. Polymerase chain reaction (PCR)–restri...

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Veröffentlicht in:	Molecular carcinogenesis 2012-10, Vol.51 (S1), p.E32-E41
Hauptverfasser:	Naushad, Shaik Mohammad, Pavani, Addepalli, Rupasree, Yedluri, Divyya, Shree, Deepti, Sripurna, Digumarti, Raghunadha Rao, Gottumukkala, Suryanarayana Raju, Prayaga, Aruna, Kutala, Vijay Kumar
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase - genetics Body Mass Index Breast cancer Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Carbon - metabolism Case-Control Studies Enzymes - genetics Enzymes - metabolism estrogen receptor (ER) Female Folic Acid - metabolism Genotype & phenotype Glycine Hydroxymethyltransferase - genetics human epidermal growth factor receptor 2 (HER2/Neu) Humans Menopause Metabolism Methylenetetrahydrofolate Reductase (NADPH2) - genetics one-carbon metabolism phenotype plasma folate plasma homocysteine Polymorphism Polymorphism, Restriction Fragment Length progesterone receptor (PR) Thymidylate Synthase - genetics
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