$Antiurolithiatic activity of saponin rich fraction from the fruits of Solanum xanthocarpum Schrad. & Wendl. (Solanaceae) against ethylene glycol induced urolithiasis in rats$

Antiurolithiatic activity of saponin rich fraction from the fruits of Solanum xanthocarpum Schrad. & Wendl. (Solanaceae) against ethylene glycol induced urolithiasis in rats

A well-known traditional herb Solanum xanthocarpum is widely used in India for the management of different ailments including urolithiasis. This study was designed to rationalize the use of Solanum xanthocarpum in kidney stone and to investigate its mechanism of action. The saponin rich fraction pre...

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Veröffentlicht in:	Journal of ethnopharmacology 2012-10, Vol.144 (1), p.160-170
Hauptverfasser:	Patel, Paras K., Patel, Manish A., Vyas, Bhavin A., Shah, Dinesh R., Gandhi, Tejal R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiurolithiatic calcium oxalate Calcium Oxalate - chemistry Calcium Oxalate - urine catalase Crystallization Disease Models, Animal drinking water Ethylene Glycol Female Fruit fruits glutathione histopathology in vivo studies kidneys Male malondialdehyde mechanism of action oxidative stress Phytotherapy Plant Extracts - analysis Plant Extracts - therapeutic use Rats Rats, Wistar renal calculi renal function Saponin rich fraction Saponins - analysis Saponins - therapeutic use Solanum Solanum virginianum Solanum xanthocarpum Toxicity Tests, Acute urine Urolithiasis - chemically induced Urolithiasis - drug therapy Urolithiasis - pathology Urolithiasis - urine
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