An amperometric hemoglobin A1c biosensor based on immobilization of fructosyl amino acid oxidase onto zinc oxide nanoparticles–polypyrrole film

Measurement of hemoglobin A1c (HbA1c, glycated hemoglobin) level in blood provides the long-term glucose level in diabetic patients without the influence of short-term fluctuations. The existing methods for HbA1c determination, including biosensors, suffer from insufficient sensitivity, detection li...

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Veröffentlicht in:	Analytical biochemistry 2012-11, Vol.430 (2), p.156-162
Hauptverfasser:	Chawla, Sheetal, Pundir, Chandra Shekhar
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amino Acid Oxidoreductases - chemistry Amino Acid Oxidoreductases - metabolism Amperometric biosensor Biosensing Techniques biosensors blood detection limit Electrochemical Techniques Electrodes Enzymes, Immobilized - chemistry Enzymes, Immobilized - metabolism Female films (materials) Food and Agriculture Organization Fructosyl amino acid oxidase glucose Glycated hemoglobin Glycated Hemoglobin A - analysis glycohemoglobin gold Humans Male Metal Nanoparticles - chemistry Metal Nanoparticles - ultrastructure Middle Aged nanoparticles patients platinum Polymers - chemistry Polypyrrole proteinases Pyrroles - chemistry Signal-To-Noise Ratio silver chloride storage quality valine Valine - analogs & derivatives Valine - analysis zinc oxide Zinc Oxide - chemistry Zinc oxide nanoparticles
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