Anti-Obesity Effects of Chitosan and Psyllium Husk with L-Ascorbic acid in Guinea Pigs
The aim of this study was to investigate whether L-Ascorbic acid would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo. The study was carried out with male Hartley guinea pigs for 5 weeks. The results show that chitosan itself did not influence body weight gain and food eff...
Gespeichert in:
| Veröffentlicht in: | International journal for vitamin and nutrition research 2012-04, Vol.82 (2), p.113-120 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 120 |
|---|---|
| container_issue | 2 |
| container_start_page | 113 |
| container_title | International journal for vitamin and nutrition research |
| container_volume | 82 |
| creator | SUNG CHUL JUN EUN YOUNG JUNG YANG HEE HONG PARK, Yooheon DUK HO KANG UN JAE CHANG HYUNG JOO SUH |
| description | The aim of this study was to investigate whether L-Ascorbic acid would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo. The study was carried out with male Hartley guinea pigs for 5 weeks. The results show that chitosan itself did not influence body weight gain and food efficiency ratio (FER). However, the addition of L-Ascorbic acid to chitosan decreased these parameters; the body weight gain and FER in the chitosan-2 group (high-fat diet group with 5 % chitosan containing 0.5 % L-Ascorbic acid) was significantly (p < 0.05) lower than that in F-controls (high-fat diet group), and was similar to that in controls (normal diet group). L-Ascorbic acid enhanced significantly (p < 0.05) the increases of total fecal weight and fecal fat excretion by chitosan. The addition of L-Ascorbic acid to psyllium husk did not differ from psyllium husk alone in terms of changes in weight gain, plasma lipid levels, and fat pad weight. We found that the addition of L-Ascorbic acid to chitosan influenced the reduction in body weight gain and FER, and the increase in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet. |
| doi_str_mv | 10.1024/0300-9831/a000100 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1112342952</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1112342952</sourcerecordid><originalsourceid>FETCH-LOGICAL-c331t-6f1f0b525e24eb952c04eeb8108b0d848fc72c8ffbcaa516d2c39489ad809e993</originalsourceid><addsrcrecordid>eNpFkL1OwzAURi0EoqXwACzICxJL6PVPUmesqtIiVWoHYLUcx6aGNIHcRKhvT6qGMt3hnu8Mh5BbBo8MuByDAIhSJdjYAAADOCNDliQy4oqzczI8_QfkCvEDQEyYkpdkwAUksRLJkLxNyyZE68xhaPZ07r2zDdLK09k2NBWakpoypxvcF0Vod3TZ4if9Cc2WrqIp2qrOgqXGhpyGki7aUDpDN-Edr8mFNwW6m_6OyOvT_GW2jFbrxfNsuoqsEKyJEs88ZDGPHZcuS2NuQTqXKQYqg1xJ5e2EW-V9Zo2JWZJzK1KpUpMrSF2aihF5OHq_6uq7ddjoXUDrisKUrmpRM8a4kLwzdyg7orauEGvn9Vcddqbeawb6kFMfculDLt3n7DZ3vb7Ndi4_Lf76dcB9Dxi0pvC1KW3Afy6RySRWUvwCEvJ7oQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1112342952</pqid></control><display><type>article</type><title>Anti-Obesity Effects of Chitosan and Psyllium Husk with L-Ascorbic acid in Guinea Pigs</title><source>Hogrefe eContent</source><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>SUNG CHUL JUN ; EUN YOUNG JUNG ; YANG HEE HONG ; PARK, Yooheon ; DUK HO KANG ; UN JAE CHANG ; HYUNG JOO SUH</creator><creatorcontrib>SUNG CHUL JUN ; EUN YOUNG JUNG ; YANG HEE HONG ; PARK, Yooheon ; DUK HO KANG ; UN JAE CHANG ; HYUNG JOO SUH</creatorcontrib><description>The aim of this study was to investigate whether L-Ascorbic acid would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo. The study was carried out with male Hartley guinea pigs for 5 weeks. The results show that chitosan itself did not influence body weight gain and food efficiency ratio (FER). However, the addition of L-Ascorbic acid to chitosan decreased these parameters; the body weight gain and FER in the chitosan-2 group (high-fat diet group with 5 % chitosan containing 0.5 % L-Ascorbic acid) was significantly (p < 0.05) lower than that in F-controls (high-fat diet group), and was similar to that in controls (normal diet group). L-Ascorbic acid enhanced significantly (p < 0.05) the increases of total fecal weight and fecal fat excretion by chitosan. The addition of L-Ascorbic acid to psyllium husk did not differ from psyllium husk alone in terms of changes in weight gain, plasma lipid levels, and fat pad weight. We found that the addition of L-Ascorbic acid to chitosan influenced the reduction in body weight gain and FER, and the increase in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet.</description><identifier>ISSN: 0300-9831</identifier><identifier>EISSN: 1664-2821</identifier><identifier>DOI: 10.1024/0300-9831/a000100</identifier><identifier>PMID: 23065836</identifier><identifier>CODEN: IJVNAP</identifier><language>eng</language><publisher>Bern: Huber</publisher><subject>Animals ; Anti-Obesity Agents - administration & dosage ; Ascorbic Acid - administration & dosage ; Biological and medical sciences ; Chitosan - administration & dosage ; Diet, High-Fat ; Drug Interactions ; Fats - analysis ; Feces - chemistry ; Feeding. Feeding behavior ; Fundamental and applied biological sciences. Psychology ; Guinea Pigs ; Male ; Obesity - etiology ; Obesity - prevention & control ; Psyllium - administration & dosage ; Vertebrates: anatomy and physiology, studies on body, several organs or systems ; Weight Gain - drug effects</subject><ispartof>International journal for vitamin and nutrition research, 2012-04, Vol.82 (2), p.113-120</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c331t-6f1f0b525e24eb952c04eeb8108b0d848fc72c8ffbcaa516d2c39489ad809e993</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26467584$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23065836$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SUNG CHUL JUN</creatorcontrib><creatorcontrib>EUN YOUNG JUNG</creatorcontrib><creatorcontrib>YANG HEE HONG</creatorcontrib><creatorcontrib>PARK, Yooheon</creatorcontrib><creatorcontrib>DUK HO KANG</creatorcontrib><creatorcontrib>UN JAE CHANG</creatorcontrib><creatorcontrib>HYUNG JOO SUH</creatorcontrib><title>Anti-Obesity Effects of Chitosan and Psyllium Husk with L-Ascorbic acid in Guinea Pigs</title><title>International journal for vitamin and nutrition research</title><addtitle>Int J Vitam Nutr Res</addtitle><description>The aim of this study was to investigate whether L-Ascorbic acid would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo. The study was carried out with male Hartley guinea pigs for 5 weeks. The results show that chitosan itself did not influence body weight gain and food efficiency ratio (FER). However, the addition of L-Ascorbic acid to chitosan decreased these parameters; the body weight gain and FER in the chitosan-2 group (high-fat diet group with 5 % chitosan containing 0.5 % L-Ascorbic acid) was significantly (p < 0.05) lower than that in F-controls (high-fat diet group), and was similar to that in controls (normal diet group). L-Ascorbic acid enhanced significantly (p < 0.05) the increases of total fecal weight and fecal fat excretion by chitosan. The addition of L-Ascorbic acid to psyllium husk did not differ from psyllium husk alone in terms of changes in weight gain, plasma lipid levels, and fat pad weight. We found that the addition of L-Ascorbic acid to chitosan influenced the reduction in body weight gain and FER, and the increase in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet.</description><subject>Animals</subject><subject>Anti-Obesity Agents - administration & dosage</subject><subject>Ascorbic Acid - administration & dosage</subject><subject>Biological and medical sciences</subject><subject>Chitosan - administration & dosage</subject><subject>Diet, High-Fat</subject><subject>Drug Interactions</subject><subject>Fats - analysis</subject><subject>Feces - chemistry</subject><subject>Feeding. Feeding behavior</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Guinea Pigs</subject><subject>Male</subject><subject>Obesity - etiology</subject><subject>Obesity - prevention & control</subject><subject>Psyllium - administration & dosage</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><subject>Weight Gain - drug effects</subject><issn>0300-9831</issn><issn>1664-2821</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkL1OwzAURi0EoqXwACzICxJL6PVPUmesqtIiVWoHYLUcx6aGNIHcRKhvT6qGMt3hnu8Mh5BbBo8MuByDAIhSJdjYAAADOCNDliQy4oqzczI8_QfkCvEDQEyYkpdkwAUksRLJkLxNyyZE68xhaPZ07r2zDdLK09k2NBWakpoypxvcF0Vod3TZ4if9Cc2WrqIp2qrOgqXGhpyGki7aUDpDN-Edr8mFNwW6m_6OyOvT_GW2jFbrxfNsuoqsEKyJEs88ZDGPHZcuS2NuQTqXKQYqg1xJ5e2EW-V9Zo2JWZJzK1KpUpMrSF2aihF5OHq_6uq7ddjoXUDrisKUrmpRM8a4kLwzdyg7orauEGvn9Vcddqbeawb6kFMfculDLt3n7DZ3vb7Ndi4_Lf76dcB9Dxi0pvC1KW3Afy6RySRWUvwCEvJ7oQ</recordid><startdate>20120401</startdate><enddate>20120401</enddate><creator>SUNG CHUL JUN</creator><creator>EUN YOUNG JUNG</creator><creator>YANG HEE HONG</creator><creator>PARK, Yooheon</creator><creator>DUK HO KANG</creator><creator>UN JAE CHANG</creator><creator>HYUNG JOO SUH</creator><general>Huber</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120401</creationdate><title>Anti-Obesity Effects of Chitosan and Psyllium Husk with L-Ascorbic acid in Guinea Pigs</title><author>SUNG CHUL JUN ; EUN YOUNG JUNG ; YANG HEE HONG ; PARK, Yooheon ; DUK HO KANG ; UN JAE CHANG ; HYUNG JOO SUH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c331t-6f1f0b525e24eb952c04eeb8108b0d848fc72c8ffbcaa516d2c39489ad809e993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Animals</topic><topic>Anti-Obesity Agents - administration & dosage</topic><topic>Ascorbic Acid - administration & dosage</topic><topic>Biological and medical sciences</topic><topic>Chitosan - administration & dosage</topic><topic>Diet, High-Fat</topic><topic>Drug Interactions</topic><topic>Fats - analysis</topic><topic>Feces - chemistry</topic><topic>Feeding. Feeding behavior</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Guinea Pigs</topic><topic>Male</topic><topic>Obesity - etiology</topic><topic>Obesity - prevention & control</topic><topic>Psyllium - administration & dosage</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><topic>Weight Gain - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SUNG CHUL JUN</creatorcontrib><creatorcontrib>EUN YOUNG JUNG</creatorcontrib><creatorcontrib>YANG HEE HONG</creatorcontrib><creatorcontrib>PARK, Yooheon</creatorcontrib><creatorcontrib>DUK HO KANG</creatorcontrib><creatorcontrib>UN JAE CHANG</creatorcontrib><creatorcontrib>HYUNG JOO SUH</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal for vitamin and nutrition research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SUNG CHUL JUN</au><au>EUN YOUNG JUNG</au><au>YANG HEE HONG</au><au>PARK, Yooheon</au><au>DUK HO KANG</au><au>UN JAE CHANG</au><au>HYUNG JOO SUH</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anti-Obesity Effects of Chitosan and Psyllium Husk with L-Ascorbic acid in Guinea Pigs</atitle><jtitle>International journal for vitamin and nutrition research</jtitle><addtitle>Int J Vitam Nutr Res</addtitle><date>2012-04-01</date><risdate>2012</risdate><volume>82</volume><issue>2</issue><spage>113</spage><epage>120</epage><pages>113-120</pages><issn>0300-9831</issn><eissn>1664-2821</eissn><coden>IJVNAP</coden><abstract>The aim of this study was to investigate whether L-Ascorbic acid would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo. The study was carried out with male Hartley guinea pigs for 5 weeks. The results show that chitosan itself did not influence body weight gain and food efficiency ratio (FER). However, the addition of L-Ascorbic acid to chitosan decreased these parameters; the body weight gain and FER in the chitosan-2 group (high-fat diet group with 5 % chitosan containing 0.5 % L-Ascorbic acid) was significantly (p < 0.05) lower than that in F-controls (high-fat diet group), and was similar to that in controls (normal diet group). L-Ascorbic acid enhanced significantly (p < 0.05) the increases of total fecal weight and fecal fat excretion by chitosan. The addition of L-Ascorbic acid to psyllium husk did not differ from psyllium husk alone in terms of changes in weight gain, plasma lipid levels, and fat pad weight. We found that the addition of L-Ascorbic acid to chitosan influenced the reduction in body weight gain and FER, and the increase in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet.</abstract><cop>Bern</cop><pub>Huber</pub><pmid>23065836</pmid><doi>10.1024/0300-9831/a000100</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0300-9831 |
| ispartof | International journal for vitamin and nutrition research, 2012-04, Vol.82 (2), p.113-120 |
| issn | 0300-9831 1664-2821 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1112342952 |
| source | Hogrefe eContent; MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Anti-Obesity Agents - administration & dosage Ascorbic Acid - administration & dosage Biological and medical sciences Chitosan - administration & dosage Diet, High-Fat Drug Interactions Fats - analysis Feces - chemistry Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Guinea Pigs Male Obesity - etiology Obesity - prevention & control Psyllium - administration & dosage Vertebrates: anatomy and physiology, studies on body, several organs or systems Weight Gain - drug effects |
| title | Anti-Obesity Effects of Chitosan and Psyllium Husk with L-Ascorbic acid in Guinea Pigs |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T14%3A32%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Anti-Obesity%20Effects%20of%20Chitosan%20and%20Psyllium%20Husk%20with%20L-Ascorbic%20acid%20in%20Guinea%20Pigs&rft.jtitle=International%20journal%20for%20vitamin%20and%20nutrition%20research&rft.au=SUNG%20CHUL%20JUN&rft.date=2012-04-01&rft.volume=82&rft.issue=2&rft.spage=113&rft.epage=120&rft.pages=113-120&rft.issn=0300-9831&rft.eissn=1664-2821&rft.coden=IJVNAP&rft_id=info:doi/10.1024/0300-9831/a000100&rft_dat=%3Cproquest_cross%3E1112342952%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1112342952&rft_id=info:pmid/23065836&rfr_iscdi=true |