Microsatellite polymorphisms in the EGFR, NOTCH4 and E2F4 genes and their association with breast cancer risk

The sequences of many human genes that encode proteins involved in cancer contain polymorphic microsatellites. Variations in microsatellite length may constitute risk factors in several human diseases, a possibility that has been little explored in breast cancer. Among the genes that contain polymor...

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Veröffentlicht in:	The International journal of biological markers 2012-10, Vol.27 (3), p.e219-e226
Hauptverfasser:	González-Hernández, Ana, Henríquez-Hernández, Luis Alberto, Cabrera de León, Antonio, Rodríguez-Pérez, M del Cristo, Murias-Rosales, Adolfo, Domínguez-Coello, Santiago, Brito-Díaz, Buenaventura, Almeida-González, Delia, Aguirre-Jaime, Armando, Díaz-Chico, B Nicolás
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Breast Neoplasms - genetics Breast Neoplasms - metabolism E2F4 Transcription Factor - genetics E2F4 Transcription Factor - metabolism Female Humans Microsatellite Repeats Middle Aged Polymorphism, Genetic Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Receptor, Notch4 Receptors, Notch - genetics Receptors, Notch - metabolism Receptors, Vascular Endothelial Growth Factor - genetics Receptors, Vascular Endothelial Growth Factor - metabolism Risk Factors
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