Complexome Profiling Identifies TMEM126B as a Component of the Mitochondrial Complex I Assembly Complex

Macromolecular complexes are essential players in numerous biological processes. They are often large, dynamic, and rather labile; approaches to study them are scarce. Covering masses up to ∼30 MDa, we separated the native complexome of rat heart mitochondria by blue-native and large-pore blue-nativ...

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