Morphine Metabolism in Human Skin Microsomes

For patients with severe skin wounds, topically applied morphine is an option to induce efficient analgesia due to the presence of opioid receptors in the skin. However, for topical administration it is important to know whether the substance is biotransformed in the skin as this can eventually redu...

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Veröffentlicht in:	Skin pharmacology and physiology 2012-01, Vol.25 (6), p.319-322
Hauptverfasser:	Heilmann, S., Küchler, S., Schäfer-Korting, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Analgesics, Opioid - administration & dosage Analgesics, Opioid - pharmacokinetics Biotransformation Humans Microsomes - metabolism Morphine - administration & dosage Morphine - pharmacokinetics Pain - drug therapy Short Communication Skin - metabolism
Online-Zugang:	Volltext
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