Flare Phenomenon Following Gefitinib Treatment of Lung Adenocarcinoma with Bone Metastasis

The skeleton is the most common site for distant metastasis in patients with cancer. To detect bone metastasis and evaluate the efficacy of treatment, we usually use bone scintigraphy and check serum alkaline phosphatase (ALP). However, such evaluation is sometimes difficult due to flare phenomenon....

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Veröffentlicht in:	The Tohoku Journal of Experimental Medicine 2012, Vol.228(2), pp.163-168
Hauptverfasser:	Hashisako, Mikiko, Wakamatsu, Kentarou, Ikegame, Satoshi, Kumazoe, Hiroyuki, Nagata, Nobuhiko, Kajiki, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - pathology Adenocarcinoma of Lung Alkaline Phosphatase - blood Antineoplastic Agents - therapeutic use Bone and Bones - chemistry bone metastasis Bone Neoplasms - drug therapy Bone Neoplasms - secondary bone scintigraphy flare phenomenon Gefitinib Humans lung cancer Lung Neoplasms - drug therapy Lung Neoplasms - pathology Male Middle Aged Polyphosphates - analysis Quinazolines - therapeutic use Radionuclide Imaging - methods Technetium Compounds - analysis Tomography, X-Ray Computed Treatment Outcome
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