Superhydrophobic-Superhydrophilic Micropatterning: Towards Genome-on-a-Chip Cell Microarrays
High‐density cell microarrays based on superhydrophilic microspots separated by superhydrophobic barriers have been realized. The microspots absorb water solutions, while the barriers prevent cross‐contamination, thus allowing the spots to be used as reservoirs for transfection mixtures and preventi...
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| Veröffentlicht in: | Angewandte Chemie International Edition 2011-08, Vol.50 (36), p.8424-8427 |
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| container_end_page | 8427 |
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| container_issue | 36 |
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| container_title | Angewandte Chemie International Edition |
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| creator | Geyer, Florian L. Ueda, Erica Liebel, Urban Grau, Nicole Levkin, Pavel A. |
| description | High‐density cell microarrays based on superhydrophilic microspots separated by superhydrophobic barriers have been realized. The microspots absorb water solutions, while the barriers prevent cross‐contamination, thus allowing the spots to be used as reservoirs for transfection mixtures and preventing cell proliferation and cell migration between the microspots. The picture shows four cell types after two days of culturing on the microarray. |
| doi_str_mv | 10.1002/anie.201102545 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1433-7851 |
| ispartof | Angewandte Chemie International Edition, 2011-08, Vol.50 (36), p.8424-8427 |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Animals Cell Line, Tumor cell microarrays cell transfection Genome HEK293 Cells high-throughput screening Humans Hydrophobic and Hydrophilic Interactions Luminescent Proteins - chemistry Microscopy, Confocal polymers Polymethacrylic Acids - chemistry Porosity Rats superhydrophobicity Tissue Array Analysis Ultraviolet Rays |
| title | Superhydrophobic-Superhydrophilic Micropatterning: Towards Genome-on-a-Chip Cell Microarrays |
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