Statin-Induced Immunomodulation Alters Peripheral Invariant Natural Killer T-cell Prevalence in Hyperlipidemic Patients

Purpose To assess the difference in the prevalence of invariant Natural Killer T (iNKT) lymphocytes between hyperlipidemic and control individuals and to evaluate changes in iNKT cell levels after 6 months lipid lowering therapy. Methods A total of 77 hyperlipidemic individuals (54 ± 5 years) were a...

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Veröffentlicht in:	Cardiovascular drugs and therapy 2012-08, Vol.26 (4), p.293-299
Hauptverfasser:	Nakou, Evangelia, Babageorgakas, Prodromos, Bouchliou, Irene, Tziakas, Dimitrios N., Miltiades, Paraskevi, Spanoudakis, Emmanouil, Margaritis, Dimitrios, Kotsianidis, Ioannis, Stakos, Dimitrios A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticholesteremic Agents - immunology Anticholesteremic Agents - pharmacology Azetidines - immunology Azetidines - pharmacology Biological and medical sciences Cardiology Cardiovascular system Cholesterol, HDL - blood Cholesterol, HDL - immunology Cholesterol, LDL - blood Cholesterol, LDL - immunology Disorders of blood lipids. Hyperlipoproteinemia Ezetimibe Female Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - immunology Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology Hyperlipidemias - blood Hyperlipidemias - drug therapy Hyperlipidemias - immunology Immunomodulation - drug effects Immunomodulation - immunology Male Medical sciences Medicine Medicine & Public Health Metabolic diseases Middle Aged Natural Killer T-Cells - drug effects Natural Killer T-Cells - immunology Pharmacology. Drug treatments Prevalence Simvastatin - immunology Simvastatin - pharmacology Triglycerides - blood Triglycerides - immunology
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