Safety and efficacy of an E2 glycoprotein subunit vaccine produced in mammalian cells to prevent experimental infection with bovine viral diarrhoea virus in cattle

Bovine viral diarrhea (BVD) infection caused by bovine viral diarrhea virus (BVDV), a Pestivirus of the Flaviviridae family, is an important cause of morbidity, mortality and economical losses in cattle worldwide. E2 protein is the major glycoprotein of BVDV envelope and the main target for neutrali...

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Veröffentlicht in:	Veterinary research communications 2012-09, Vol.36 (3), p.157-164
Hauptverfasser:	Pecora, Andrea, Aguirreburualde, María Sol Pérez, Aguirreburualde, Alejandra, Leunda, Maria Rosa, Odeon, Anselmo, Chiavenna, Sebastián, Bochoeyer, Diego, Spitteler, Marcelo, Filippi, Jorge L., Dus Santos, Maria J., Levy, Susana M., Wigdorovitz, Andrés
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Bovine viral diarrhea virus Bovine Virus Diarrhea-Mucosal Disease - immunology Bovine Virus Diarrhea-Mucosal Disease - prevention & control Bovine Virus Diarrhea-Mucosal Disease - virology Cattle Cattle Diseases - immunology Cattle Diseases - prevention & control Diarrhea Virus 1, Bovine Viral - immunology DNA, Viral - genetics DNA, Viral - immunology Enzyme-Linked Immunosorbent Assay Flaviviridae Glycoproteins - adverse effects Glycoproteins - genetics Glycoproteins - immunology Guinea Pigs Life Sciences Neutralization Tests Original Article Pestivirus Recombinant Proteins - adverse effects Recombinant Proteins - genetics Recombinant Proteins - immunology Vaccines, Subunit - administration & dosage Vaccines, Subunit - adverse effects Vaccines, Subunit - immunology Veterinary Medicine/Veterinary Science Viral Envelope Proteins - adverse effects Viral Envelope Proteins - genetics Viral Envelope Proteins - immunology Viral Vaccines - administration & dosage Viral Vaccines - adverse effects Viral Vaccines - immunology Zoology
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