ω-Phonetoxin-IIA: a calcium channel blocker from the spider Phoneutria nigriventer

A peptide with neurotoxic effect on mammals, purified from the venom of the spider Phoneutria nigriventer, was studied regarding its primary structure and its effects on voltage-gated calcium channels. The peptide, named ω-phonetoxin-IIA, has 76 amino acids residues, with 14 Cys forming 7 disulphide...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pflügers Archiv 1998-07, Vol.436 (4), p.545-552
Hauptverfasser:	Cassola, A C, Jaffe, H, Fales, H M, Afeche, S C, Magnoli, F, Cipolla-Neto, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Araneae Calcium - metabolism Calcium Channel Blockers - chemistry Calcium Channels - metabolism Cells, Cultured Electrophysiology Female Ganglia, Spinal - cytology Insulin-Secreting Cells - cytology Insulin-Secreting Cells - metabolism Male Molecular Sequence Data Neurons - cytology Neurons - metabolism Peptides - chemistry Rats Rats, Wistar Sequence Alignment Spider Venoms - chemistry Spider Venoms - genetics Spiders - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!