Bicuculline block of small-conductance calcium-activated potassium channels

Small-conductance calcium-activated potassium channels (SK channels) are gated solely by intracellular calcium ions and their activity is responsible for the slow afterhyperpolarization (AHP) that follows an action potential in many excitable cells. Brain slice studies commonly employ a methyl deriv...

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Veröffentlicht in:	Pflügers Archiv 1999-08, Vol.438 (3), p.314-321
Hauptverfasser:	Khawaled, R, Bruening-Wright, A, Adelman, J P, Maylie, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Action potential Animals Apamin - pharmacology Bicuculline - pharmacology Calcium - pharmacology Electric Conductivity Female GABA Antagonists - pharmacology Gene Expression Kinetics Oocytes - metabolism Potassium Channel Blockers Potassium Channels - genetics Potassium Channels - physiology Recombinant Proteins Xenopus
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