Preoperative hypoalbuminemia is a major risk factor for acute kidney injury following off-pump coronary artery bypass surgery
Purpose To investigate the association between preoperative low serum albumin level and acute kidney injury (AKI) after off-pump coronary artery bypass surgery (OPCAB) Method We assessed preoperative and perioperative risk factors, and preoperative serum albumin concentration in 1,182 consecutive ad...
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| Veröffentlicht in: | Intensive care medicine 2012-09, Vol.38 (9), p.1478-1486 |
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| creator | Lee, Eun-Ho Baek, Seung-Hee Chin, Ji-Hyun Choi, Dae-Kee Son, Hyo-Jung Kim, Wook-Jong Hahm, Kyung-Don Sim, Ji-Yeon Choi, In-Cheol |
| description | Purpose
To investigate the association between preoperative low serum albumin level and acute kidney injury (AKI) after off-pump coronary artery bypass surgery (OPCAB)
Method
We assessed preoperative and perioperative risk factors, and preoperative serum albumin concentration in 1,182 consecutive adult patients with preoperative normal renal function who underwent OPCAB surgery. Each patient was categorized by maximal Acute Kidney Injury Network (AKIN) criteria based on creatinine changes within the first 48 h after OPCAB. Logistic regression and propensity analyses were performed to evaluate the association between preoperative low serum albumin level and postoperative AKI.
Results
Of the 1,182 patients, 334 (28.3%) developed AKI. Risk factors for AKI were old age, diabetes mellitus, maximal cardiovascular component of the sequential organ failure assessment score, perioperative transfusion, and postoperative C-reactive protein concentration. The risk of AKI was negatively correlated with the volume of crystalloid infused during surgery. A preoperative serum albumin level of |
| doi_str_mv | 10.1007/s00134-012-2599-8 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1093455849</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A724315192</galeid><sourcerecordid>A724315192</sourcerecordid><originalsourceid>FETCH-LOGICAL-c606t-89e92928637fb390f2fd0a2e16c6e713ba3db0ebef68a0595d02b41f4fb1269a3</originalsourceid><addsrcrecordid>eNqNkk1v1DAQhiNERZfCD-CCLCEkLin-ihMfq4ovqRI9lHM0cezF28QOdlK0B_47s9otBbRIaGSN7XnG9njeonjB6DmjtH6bKWVClpTxkldal82jYsWk4CXjonlcrKiQvJRK8tPiac4bpGtVsSfFKeeKNVTzVfHjOtk42QSzv7Pk63aKMHTL6IMdPRCfCZARNjGR5PMtcWBmnDscYJbZklvfB7slPmyWtMX9YYjffViT6Fw5LeNETEwxAMYgzRZdt50gZ5KXtMbls-LEwZDt84M_K768f3dz-bG8-vzh0-XFVWkUVXPZaKu55o0SteuEpo67ngK3TBllayY6EH1HbWedaoBWuuop7yRz0nWMKw3irHizP3dK8dti89yOPhs7DBBsXHLLqBayqhqp_wMVUlUNGqKv_kI3cUkBC9lRNVcVrdgDtYbBtj64OCcwu0Pbi5pLwSqmOVLlEWptA7ZmiME6j9t_8OdHeLQeG2eOJrB9gkkx52RdOyU_Ymfwre1OTe1eTS2qqd2pqW0w5-WhwKUbbf8r414-CLw-AJANDC5BMD4_cIprxmqBHN9zGUMBO__7T_3r9p9vI-Do</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1037265051</pqid></control><display><type>article</type><title>Preoperative hypoalbuminemia is a major risk factor for acute kidney injury following off-pump coronary artery bypass surgery</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Lee, Eun-Ho ; Baek, Seung-Hee ; Chin, Ji-Hyun ; Choi, Dae-Kee ; Son, Hyo-Jung ; Kim, Wook-Jong ; Hahm, Kyung-Don ; Sim, Ji-Yeon ; Choi, In-Cheol</creator><creatorcontrib>Lee, Eun-Ho ; Baek, Seung-Hee ; Chin, Ji-Hyun ; Choi, Dae-Kee ; Son, Hyo-Jung ; Kim, Wook-Jong ; Hahm, Kyung-Don ; Sim, Ji-Yeon ; Choi, In-Cheol</creatorcontrib><description>Purpose
To investigate the association between preoperative low serum albumin level and acute kidney injury (AKI) after off-pump coronary artery bypass surgery (OPCAB)
Method
We assessed preoperative and perioperative risk factors, and preoperative serum albumin concentration in 1,182 consecutive adult patients with preoperative normal renal function who underwent OPCAB surgery. Each patient was categorized by maximal Acute Kidney Injury Network (AKIN) criteria based on creatinine changes within the first 48 h after OPCAB. Logistic regression and propensity analyses were performed to evaluate the association between preoperative low serum albumin level and postoperative AKI.
Results
Of the 1,182 patients, 334 (28.3%) developed AKI. Risk factors for AKI were old age, diabetes mellitus, maximal cardiovascular component of the sequential organ failure assessment score, perioperative transfusion, and postoperative C-reactive protein concentration. The risk of AKI was negatively correlated with the volume of crystalloid infused during surgery. A preoperative serum albumin level of <4.0 g/dl was independently associated
I
th postoperative AKI [multivariable logistic analysis: odds ratio (OR) 1.83, 95 % confidence interval (CI) 1.27–2.64;
P
= 0.001; propensity analysis: OR 1.62, 95 % CI 1.12–2.35;
P
= 0.011). AKI was associated with prolonged stay in the intensive care unit and hospital and a high mortality rate.
Conclusions
Preoperative low serum albumin level is an independent risk factor for AKI, and postoperative AKI is associated with poor outcomes after OPCAB in patients with preoperative normal renal function.</description><identifier>ISSN: 0342-4642</identifier><identifier>EISSN: 1432-1238</identifier><identifier>DOI: 10.1007/s00134-012-2599-8</identifier><identifier>PMID: 22618092</identifier><identifier>CODEN: ICMED9</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Acute Kidney Injury - diagnosis ; Acute Kidney Injury - epidemiology ; Acute Kidney Injury - mortality ; Aged ; Albumin ; Albumins - analysis ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Anesthesiology ; Biological and medical sciences ; Blood ; Confidence Intervals ; Coronary artery bypass ; Coronary Artery Bypass, Off-Pump - adverse effects ; Coronary vessels ; Creatinine ; Critical Care Medicine ; Diabetes ; Emergency Medicine ; Female ; Health aspects ; Health Status Indicators ; Heart surgery ; Hemoglobin ; Hospitals ; Humans ; Hypoalbuminemia - diagnosis ; Hypoalbuminemia - pathology ; Injuries ; Intensive ; Intensive care ; Intensive care medicine ; Intensive care units ; Kidney ; Kidneys ; Korea ; Logistic Models ; Male ; Medical research ; Medical sciences ; Medicine ; Medicine & Public Health ; Medicine, Experimental ; Middle Aged ; Morbidity ; Mortality ; Odds Ratio ; Organs ; Original ; Pain Medicine ; Pediatrics ; Pneumology/Respiratory System ; Preoperative Care - methods ; Prognosis ; Remifentanil ; Renal function ; Retrospective Studies ; Risk Factors ; Surgery ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the heart ; Veins & arteries</subject><ispartof>Intensive care medicine, 2012-09, Vol.38 (9), p.1478-1486</ispartof><rights>Copyright jointly held by Springer and ESICM 2012</rights><rights>2015 INIST-CNRS</rights><rights>COPYRIGHT 2012 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c606t-89e92928637fb390f2fd0a2e16c6e713ba3db0ebef68a0595d02b41f4fb1269a3</citedby><cites>FETCH-LOGICAL-c606t-89e92928637fb390f2fd0a2e16c6e713ba3db0ebef68a0595d02b41f4fb1269a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00134-012-2599-8$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00134-012-2599-8$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26291173$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22618092$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Eun-Ho</creatorcontrib><creatorcontrib>Baek, Seung-Hee</creatorcontrib><creatorcontrib>Chin, Ji-Hyun</creatorcontrib><creatorcontrib>Choi, Dae-Kee</creatorcontrib><creatorcontrib>Son, Hyo-Jung</creatorcontrib><creatorcontrib>Kim, Wook-Jong</creatorcontrib><creatorcontrib>Hahm, Kyung-Don</creatorcontrib><creatorcontrib>Sim, Ji-Yeon</creatorcontrib><creatorcontrib>Choi, In-Cheol</creatorcontrib><title>Preoperative hypoalbuminemia is a major risk factor for acute kidney injury following off-pump coronary artery bypass surgery</title><title>Intensive care medicine</title><addtitle>Intensive Care Med</addtitle><addtitle>Intensive Care Med</addtitle><description>Purpose
To investigate the association between preoperative low serum albumin level and acute kidney injury (AKI) after off-pump coronary artery bypass surgery (OPCAB)
Method
We assessed preoperative and perioperative risk factors, and preoperative serum albumin concentration in 1,182 consecutive adult patients with preoperative normal renal function who underwent OPCAB surgery. Each patient was categorized by maximal Acute Kidney Injury Network (AKIN) criteria based on creatinine changes within the first 48 h after OPCAB. Logistic regression and propensity analyses were performed to evaluate the association between preoperative low serum albumin level and postoperative AKI.
Results
Of the 1,182 patients, 334 (28.3%) developed AKI. Risk factors for AKI were old age, diabetes mellitus, maximal cardiovascular component of the sequential organ failure assessment score, perioperative transfusion, and postoperative C-reactive protein concentration. The risk of AKI was negatively correlated with the volume of crystalloid infused during surgery. A preoperative serum albumin level of <4.0 g/dl was independently associated
I
th postoperative AKI [multivariable logistic analysis: odds ratio (OR) 1.83, 95 % confidence interval (CI) 1.27–2.64;
P
= 0.001; propensity analysis: OR 1.62, 95 % CI 1.12–2.35;
P
= 0.011). AKI was associated with prolonged stay in the intensive care unit and hospital and a high mortality rate.
Conclusions
Preoperative low serum albumin level is an independent risk factor for AKI, and postoperative AKI is associated with poor outcomes after OPCAB in patients with preoperative normal renal function.</description><subject>Acute Kidney Injury - diagnosis</subject><subject>Acute Kidney Injury - epidemiology</subject><subject>Acute Kidney Injury - mortality</subject><subject>Aged</subject><subject>Albumin</subject><subject>Albumins - analysis</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Anesthesiology</subject><subject>Biological and medical sciences</subject><subject>Blood</subject><subject>Confidence Intervals</subject><subject>Coronary artery bypass</subject><subject>Coronary Artery Bypass, Off-Pump - adverse effects</subject><subject>Coronary vessels</subject><subject>Creatinine</subject><subject>Critical Care Medicine</subject><subject>Diabetes</subject><subject>Emergency Medicine</subject><subject>Female</subject><subject>Health aspects</subject><subject>Health Status Indicators</subject><subject>Heart surgery</subject><subject>Hemoglobin</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hypoalbuminemia - diagnosis</subject><subject>Hypoalbuminemia - pathology</subject><subject>Injuries</subject><subject>Intensive</subject><subject>Intensive care</subject><subject>Intensive care medicine</subject><subject>Intensive care units</subject><subject>Kidney</subject><subject>Kidneys</subject><subject>Korea</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Medicine, Experimental</subject><subject>Middle Aged</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>Odds Ratio</subject><subject>Organs</subject><subject>Original</subject><subject>Pain Medicine</subject><subject>Pediatrics</subject><subject>Pneumology/Respiratory System</subject><subject>Preoperative Care - methods</subject><subject>Prognosis</subject><subject>Remifentanil</subject><subject>Renal function</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Surgery</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the heart</subject><subject>Veins & arteries</subject><issn>0342-4642</issn><issn>1432-1238</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkk1v1DAQhiNERZfCD-CCLCEkLin-ihMfq4ovqRI9lHM0cezF28QOdlK0B_47s9otBbRIaGSN7XnG9njeonjB6DmjtH6bKWVClpTxkldal82jYsWk4CXjonlcrKiQvJRK8tPiac4bpGtVsSfFKeeKNVTzVfHjOtk42QSzv7Pk63aKMHTL6IMdPRCfCZARNjGR5PMtcWBmnDscYJbZklvfB7slPmyWtMX9YYjffViT6Fw5LeNETEwxAMYgzRZdt50gZ5KXtMbls-LEwZDt84M_K768f3dz-bG8-vzh0-XFVWkUVXPZaKu55o0SteuEpo67ngK3TBllayY6EH1HbWedaoBWuuop7yRz0nWMKw3irHizP3dK8dti89yOPhs7DBBsXHLLqBayqhqp_wMVUlUNGqKv_kI3cUkBC9lRNVcVrdgDtYbBtj64OCcwu0Pbi5pLwSqmOVLlEWptA7ZmiME6j9t_8OdHeLQeG2eOJrB9gkkx52RdOyU_Ymfwre1OTe1eTS2qqd2pqW0w5-WhwKUbbf8r414-CLw-AJANDC5BMD4_cIprxmqBHN9zGUMBO__7T_3r9p9vI-Do</recordid><startdate>20120901</startdate><enddate>20120901</enddate><creator>Lee, Eun-Ho</creator><creator>Baek, Seung-Hee</creator><creator>Chin, Ji-Hyun</creator><creator>Choi, Dae-Kee</creator><creator>Son, Hyo-Jung</creator><creator>Kim, Wook-Jong</creator><creator>Hahm, Kyung-Don</creator><creator>Sim, Ji-Yeon</creator><creator>Choi, In-Cheol</creator><general>Springer-Verlag</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>7U1</scope><scope>7U2</scope><scope>C1K</scope></search><sort><creationdate>20120901</creationdate><title>Preoperative hypoalbuminemia is a major risk factor for acute kidney injury following off-pump coronary artery bypass surgery</title><author>Lee, Eun-Ho ; Baek, Seung-Hee ; Chin, Ji-Hyun ; Choi, Dae-Kee ; Son, Hyo-Jung ; Kim, Wook-Jong ; Hahm, Kyung-Don ; Sim, Ji-Yeon ; Choi, In-Cheol</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c606t-89e92928637fb390f2fd0a2e16c6e713ba3db0ebef68a0595d02b41f4fb1269a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Acute Kidney Injury - diagnosis</topic><topic>Acute Kidney Injury - epidemiology</topic><topic>Acute Kidney Injury - mortality</topic><topic>Aged</topic><topic>Albumin</topic><topic>Albumins - analysis</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Anesthesiology</topic><topic>Biological and medical sciences</topic><topic>Blood</topic><topic>Confidence Intervals</topic><topic>Coronary artery bypass</topic><topic>Coronary Artery Bypass, Off-Pump - adverse effects</topic><topic>Coronary vessels</topic><topic>Creatinine</topic><topic>Critical Care Medicine</topic><topic>Diabetes</topic><topic>Emergency Medicine</topic><topic>Female</topic><topic>Health aspects</topic><topic>Health Status Indicators</topic><topic>Heart surgery</topic><topic>Hemoglobin</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Hypoalbuminemia - diagnosis</topic><topic>Hypoalbuminemia - pathology</topic><topic>Injuries</topic><topic>Intensive</topic><topic>Intensive care</topic><topic>Intensive care medicine</topic><topic>Intensive care units</topic><topic>Kidney</topic><topic>Kidneys</topic><topic>Korea</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Medicine, Experimental</topic><topic>Middle Aged</topic><topic>Morbidity</topic><topic>Mortality</topic><topic>Odds Ratio</topic><topic>Organs</topic><topic>Original</topic><topic>Pain Medicine</topic><topic>Pediatrics</topic><topic>Pneumology/Respiratory System</topic><topic>Preoperative Care - methods</topic><topic>Prognosis</topic><topic>Remifentanil</topic><topic>Renal function</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Surgery</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the heart</topic><topic>Veins & arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Eun-Ho</creatorcontrib><creatorcontrib>Baek, Seung-Hee</creatorcontrib><creatorcontrib>Chin, Ji-Hyun</creatorcontrib><creatorcontrib>Choi, Dae-Kee</creatorcontrib><creatorcontrib>Son, Hyo-Jung</creatorcontrib><creatorcontrib>Kim, Wook-Jong</creatorcontrib><creatorcontrib>Hahm, Kyung-Don</creatorcontrib><creatorcontrib>Sim, Ji-Yeon</creatorcontrib><creatorcontrib>Choi, In-Cheol</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Intensive care medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Eun-Ho</au><au>Baek, Seung-Hee</au><au>Chin, Ji-Hyun</au><au>Choi, Dae-Kee</au><au>Son, Hyo-Jung</au><au>Kim, Wook-Jong</au><au>Hahm, Kyung-Don</au><au>Sim, Ji-Yeon</au><au>Choi, In-Cheol</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preoperative hypoalbuminemia is a major risk factor for acute kidney injury following off-pump coronary artery bypass surgery</atitle><jtitle>Intensive care medicine</jtitle><stitle>Intensive Care Med</stitle><addtitle>Intensive Care Med</addtitle><date>2012-09-01</date><risdate>2012</risdate><volume>38</volume><issue>9</issue><spage>1478</spage><epage>1486</epage><pages>1478-1486</pages><issn>0342-4642</issn><eissn>1432-1238</eissn><coden>ICMED9</coden><abstract>Purpose
To investigate the association between preoperative low serum albumin level and acute kidney injury (AKI) after off-pump coronary artery bypass surgery (OPCAB)
Method
We assessed preoperative and perioperative risk factors, and preoperative serum albumin concentration in 1,182 consecutive adult patients with preoperative normal renal function who underwent OPCAB surgery. Each patient was categorized by maximal Acute Kidney Injury Network (AKIN) criteria based on creatinine changes within the first 48 h after OPCAB. Logistic regression and propensity analyses were performed to evaluate the association between preoperative low serum albumin level and postoperative AKI.
Results
Of the 1,182 patients, 334 (28.3%) developed AKI. Risk factors for AKI were old age, diabetes mellitus, maximal cardiovascular component of the sequential organ failure assessment score, perioperative transfusion, and postoperative C-reactive protein concentration. The risk of AKI was negatively correlated with the volume of crystalloid infused during surgery. A preoperative serum albumin level of <4.0 g/dl was independently associated
I
th postoperative AKI [multivariable logistic analysis: odds ratio (OR) 1.83, 95 % confidence interval (CI) 1.27–2.64;
P
= 0.001; propensity analysis: OR 1.62, 95 % CI 1.12–2.35;
P
= 0.011). AKI was associated with prolonged stay in the intensive care unit and hospital and a high mortality rate.
Conclusions
Preoperative low serum albumin level is an independent risk factor for AKI, and postoperative AKI is associated with poor outcomes after OPCAB in patients with preoperative normal renal function.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>22618092</pmid><doi>10.1007/s00134-012-2599-8</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0342-4642 |
| ispartof | Intensive care medicine, 2012-09, Vol.38 (9), p.1478-1486 |
| issn | 0342-4642 1432-1238 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Acute Kidney Injury - diagnosis Acute Kidney Injury - epidemiology Acute Kidney Injury - mortality Aged Albumin Albumins - analysis Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthesiology Biological and medical sciences Blood Confidence Intervals Coronary artery bypass Coronary Artery Bypass, Off-Pump - adverse effects Coronary vessels Creatinine Critical Care Medicine Diabetes Emergency Medicine Female Health aspects Health Status Indicators Heart surgery Hemoglobin Hospitals Humans Hypoalbuminemia - diagnosis Hypoalbuminemia - pathology Injuries Intensive Intensive care Intensive care medicine Intensive care units Kidney Kidneys Korea Logistic Models Male Medical research Medical sciences Medicine Medicine & Public Health Medicine, Experimental Middle Aged Morbidity Mortality Odds Ratio Organs Original Pain Medicine Pediatrics Pneumology/Respiratory System Preoperative Care - methods Prognosis Remifentanil Renal function Retrospective Studies Risk Factors Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Veins & arteries |
| title | Preoperative hypoalbuminemia is a major risk factor for acute kidney injury following off-pump coronary artery bypass surgery |
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