A Search for Obligatory Paternal Alleles in a DNA Database to Find an Alleged Rapist in a Fatherless Paternity Case
: A sexual assault case resulted in a pregnancy, which was subsequently aborted. The alleged father of the fetus was unknown. Maternal and fetal types were obtained using the 11‐locus AmpFℓSTR® SGM Plus® kit. The national DNA database was searched for the paternal obligatory alleles and detected tw...
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Veröffentlicht in: | Journal of forensic sciences 2012-07, Vol.57 (4), p.1098-1101 |
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creator | Barash, Mark Reshef, Ayeleth Voskoboinik, Lev Zamir, Ashira Motro, Uzi Gafny, Ron |
description | : A sexual assault case resulted in a pregnancy, which was subsequently aborted. The alleged father of the fetus was unknown. Maternal and fetal types were obtained using the 11‐locus AmpFℓSTR® SGM Plus® kit. The national DNA database was searched for the paternal obligatory alleles and detected two suspects who could not be excluded as father of the male fetus. Additional typing using the AmpFℓSTR® Minifiler™ kit, containing three additional autosomal loci, was not sufficient to exclude either suspect. Subsequent typing using the PowerPlex® 16, containing four additional loci, and Y‐Filer™ kits resulted in excluding one suspect. Searching a database for paternal obligatory alleles can be fruitful, but is fraught with possible false positive results so that finding a match must be taken as only preliminary evidence. |
doi_str_mv | 10.1111/j.1556-4029.2012.02095.x |
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The alleged father of the fetus was unknown. Maternal and fetal types were obtained using the 11‐locus AmpFℓSTR® SGM Plus® kit. The national DNA database was searched for the paternal obligatory alleles and detected two suspects who could not be excluded as father of the male fetus. Additional typing using the AmpFℓSTR® Minifiler™ kit, containing three additional autosomal loci, was not sufficient to exclude either suspect. Subsequent typing using the PowerPlex® 16, containing four additional loci, and Y‐Filer™ kits resulted in excluding one suspect. Searching a database for paternal obligatory alleles can be fruitful, but is fraught with possible false positive results so that finding a match must be taken as only preliminary evidence.</description><identifier>ISSN: 0022-1198</identifier><identifier>EISSN: 1556-4029</identifier><identifier>DOI: 10.1111/j.1556-4029.2012.02095.x</identifier><identifier>PMID: 22390833</identifier><identifier>CODEN: JFSCAS</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Aborted Fetus ; Alleles ; AmpFℓSTR® Minifiler ; AmpFℓSTR® SGM Plus ; AmpFℓSTR® YFiler ; Chromosomes, Human, Y ; Databases, Nucleic Acid ; Deoxyribonucleic acid ; DNA ; DNA database ; DNA Fingerprinting ; Female ; Fetuses ; forensic DNA analysis ; forensic science ; Forensic sciences ; Gene loci ; Genes ; Haplotypes ; Humans ; Male ; Microsatellite Repeats ; Paternity ; Polymerase Chain Reaction ; PowerPlex® 16 ; Pregnancy ; Rape ; Sex crimes ; sexual assault</subject><ispartof>Journal of forensic sciences, 2012-07, Vol.57 (4), p.1098-1101</ispartof><rights>2012 American Academy of Forensic Sciences</rights><rights>2012 American Academy of Forensic Sciences.</rights><rights>Copyright American Society for Testing and Materials Jul 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4305-4950047b209b490177f780b4eb6b7cfc2f99fd2eb439417d155b62ff5f4690433</citedby><cites>FETCH-LOGICAL-c4305-4950047b209b490177f780b4eb6b7cfc2f99fd2eb439417d155b62ff5f4690433</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1556-4029.2012.02095.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1556-4029.2012.02095.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22390833$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Barash, Mark</creatorcontrib><creatorcontrib>Reshef, Ayeleth</creatorcontrib><creatorcontrib>Voskoboinik, Lev</creatorcontrib><creatorcontrib>Zamir, Ashira</creatorcontrib><creatorcontrib>Motro, Uzi</creatorcontrib><creatorcontrib>Gafny, Ron</creatorcontrib><title>A Search for Obligatory Paternal Alleles in a DNA Database to Find an Alleged Rapist in a Fatherless Paternity Case</title><title>Journal of forensic sciences</title><addtitle>J Forensic Sci</addtitle><description>: A sexual assault case resulted in a pregnancy, which was subsequently aborted. The alleged father of the fetus was unknown. Maternal and fetal types were obtained using the 11‐locus AmpFℓSTR® SGM Plus® kit. The national DNA database was searched for the paternal obligatory alleles and detected two suspects who could not be excluded as father of the male fetus. Additional typing using the AmpFℓSTR® Minifiler™ kit, containing three additional autosomal loci, was not sufficient to exclude either suspect. Subsequent typing using the PowerPlex® 16, containing four additional loci, and Y‐Filer™ kits resulted in excluding one suspect. Searching a database for paternal obligatory alleles can be fruitful, but is fraught with possible false positive results so that finding a match must be taken as only preliminary evidence.</description><subject>Aborted Fetus</subject><subject>Alleles</subject><subject>AmpFℓSTR® Minifiler</subject><subject>AmpFℓSTR® SGM Plus</subject><subject>AmpFℓSTR® YFiler</subject><subject>Chromosomes, Human, Y</subject><subject>Databases, Nucleic Acid</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA database</subject><subject>DNA Fingerprinting</subject><subject>Female</subject><subject>Fetuses</subject><subject>forensic DNA analysis</subject><subject>forensic science</subject><subject>Forensic sciences</subject><subject>Gene loci</subject><subject>Genes</subject><subject>Haplotypes</subject><subject>Humans</subject><subject>Male</subject><subject>Microsatellite Repeats</subject><subject>Paternity</subject><subject>Polymerase Chain Reaction</subject><subject>PowerPlex® 16</subject><subject>Pregnancy</subject><subject>Rape</subject><subject>Sex crimes</subject><subject>sexual assault</subject><issn>0022-1198</issn><issn>1556-4029</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkclO6zAYhS10EZThFZAlNneT8HvI4AWLqtwyCFHEsLbsxIZUblLsVJe-PQ4tLFjhjS35O8f6_SGECaQkrrN5SrIsTzhQkVIgNAUKIkvfd9Do--IPGgFQmhAiyn10EMIcAHKSkz20TykTUDI2QmGMH43y1Su2nccz7ZoX1Xd-je9Vb3yrHB47Z5wJuGmxwhd3Y3yheqVVMLjv8LRpa6zaT-jF1PhBLZvQb9ip6l-Nj9GwLWv6NZ7E4BHatcoFc7zdD9Hz9N_T5Cq5nV1eT8a3ScUZZAkXGQAvdBxNcwGkKGxRguZG57qobEWtELamRnMmOCnqOLnOqbWZ5bkAztgh-rvpXfrubWVCLxdNqIxzqjXdKkgCgvGM04L_AqWMClqSPKKnP9B5txp-aksxUnIaqXJDVb4LwRsrl75ZKL-OkBwcyrkcVMlBlRwcyk-H8j1GT7YPrPTC1N_BL2kRON8A_xtn1r8uljfT2XBiH1RfppY</recordid><startdate>201207</startdate><enddate>201207</enddate><creator>Barash, Mark</creator><creator>Reshef, Ayeleth</creator><creator>Voskoboinik, Lev</creator><creator>Zamir, Ashira</creator><creator>Motro, Uzi</creator><creator>Gafny, Ron</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K7.</scope><scope>7X8</scope><scope>7TM</scope></search><sort><creationdate>201207</creationdate><title>A Search for Obligatory Paternal Alleles in a DNA Database to Find an Alleged Rapist in a Fatherless Paternity Case</title><author>Barash, Mark ; Reshef, Ayeleth ; Voskoboinik, Lev ; Zamir, Ashira ; Motro, Uzi ; Gafny, Ron</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4305-4950047b209b490177f780b4eb6b7cfc2f99fd2eb439417d155b62ff5f4690433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Aborted Fetus</topic><topic>Alleles</topic><topic>AmpFℓSTR® Minifiler</topic><topic>AmpFℓSTR® SGM Plus</topic><topic>AmpFℓSTR® YFiler</topic><topic>Chromosomes, Human, Y</topic><topic>Databases, Nucleic Acid</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>DNA database</topic><topic>DNA Fingerprinting</topic><topic>Female</topic><topic>Fetuses</topic><topic>forensic DNA analysis</topic><topic>forensic science</topic><topic>Forensic sciences</topic><topic>Gene loci</topic><topic>Genes</topic><topic>Haplotypes</topic><topic>Humans</topic><topic>Male</topic><topic>Microsatellite Repeats</topic><topic>Paternity</topic><topic>Polymerase Chain Reaction</topic><topic>PowerPlex® 16</topic><topic>Pregnancy</topic><topic>Rape</topic><topic>Sex crimes</topic><topic>sexual assault</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barash, Mark</creatorcontrib><creatorcontrib>Reshef, Ayeleth</creatorcontrib><creatorcontrib>Voskoboinik, Lev</creatorcontrib><creatorcontrib>Zamir, Ashira</creatorcontrib><creatorcontrib>Motro, Uzi</creatorcontrib><creatorcontrib>Gafny, Ron</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Criminal Justice (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>Nucleic Acids Abstracts</collection><jtitle>Journal of forensic sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barash, Mark</au><au>Reshef, Ayeleth</au><au>Voskoboinik, Lev</au><au>Zamir, Ashira</au><au>Motro, Uzi</au><au>Gafny, Ron</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Search for Obligatory Paternal Alleles in a DNA Database to Find an Alleged Rapist in a Fatherless Paternity Case</atitle><jtitle>Journal of forensic sciences</jtitle><addtitle>J Forensic Sci</addtitle><date>2012-07</date><risdate>2012</risdate><volume>57</volume><issue>4</issue><spage>1098</spage><epage>1101</epage><pages>1098-1101</pages><issn>0022-1198</issn><eissn>1556-4029</eissn><coden>JFSCAS</coden><abstract>: A sexual assault case resulted in a pregnancy, which was subsequently aborted. The alleged father of the fetus was unknown. Maternal and fetal types were obtained using the 11‐locus AmpFℓSTR® SGM Plus® kit. The national DNA database was searched for the paternal obligatory alleles and detected two suspects who could not be excluded as father of the male fetus. Additional typing using the AmpFℓSTR® Minifiler™ kit, containing three additional autosomal loci, was not sufficient to exclude either suspect. Subsequent typing using the PowerPlex® 16, containing four additional loci, and Y‐Filer™ kits resulted in excluding one suspect. Searching a database for paternal obligatory alleles can be fruitful, but is fraught with possible false positive results so that finding a match must be taken as only preliminary evidence.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>22390833</pmid><doi>10.1111/j.1556-4029.2012.02095.x</doi><tpages>4</tpages></addata></record> |
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subjects | Aborted Fetus Alleles AmpFℓSTR® Minifiler AmpFℓSTR® SGM Plus AmpFℓSTR® YFiler Chromosomes, Human, Y Databases, Nucleic Acid Deoxyribonucleic acid DNA DNA database DNA Fingerprinting Female Fetuses forensic DNA analysis forensic science Forensic sciences Gene loci Genes Haplotypes Humans Male Microsatellite Repeats Paternity Polymerase Chain Reaction PowerPlex® 16 Pregnancy Rape Sex crimes sexual assault |
title | A Search for Obligatory Paternal Alleles in a DNA Database to Find an Alleged Rapist in a Fatherless Paternity Case |
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