Alcohol consumption and body weight change in postmenopausal women: results from the Women's Health Initiative

Objective: To determine whether alcohol consumption is associated with incident overweight or obesity in normal-weight, postmenopausal women. Design: Prospective cohort study considering baseline alcohol consumption and subsequent weight change over 7 years. Subjects: 15 920 normal-weight (body mass...

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Veröffentlicht in:International Journal of Obesity 2012-09, Vol.36 (9), p.1158-1164
Hauptverfasser: Thomson, C A, Wertheim, B C, Hingle, M, Wang, L, Neuhouser, M L, Gong, Z, Garcia, L, Stefanick, M L, Manson, J E
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container_end_page 1164
container_issue 9
container_start_page 1158
container_title International Journal of Obesity
container_volume 36
creator Thomson, C A
Wertheim, B C
Hingle, M
Wang, L
Neuhouser, M L
Gong, Z
Garcia, L
Stefanick, M L
Manson, J E
description Objective: To determine whether alcohol consumption is associated with incident overweight or obesity in normal-weight, postmenopausal women. Design: Prospective cohort study considering baseline alcohol consumption and subsequent weight change over 7 years. Subjects: 15 920 normal-weight (body mass index (BMI): 18.5 to
doi_str_mv 10.1038/ijo.2012.84
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Design: Prospective cohort study considering baseline alcohol consumption and subsequent weight change over 7 years. Subjects: 15 920 normal-weight (body mass index (BMI): 18.5 to &lt;25 kg m −2 ), postmenopausal women enrolled in the Women′s Health Initiative Clinical Trial. Measurements: Body weight change, and incident overweight and obesity (BMI, 25.0 to &lt;30 and ⩾30 kg m −2 ) over 7 years. Results: One-third of the 13 822 women included in the analytical cohort reported no alcohol consumption. BMI differed little between abstainers (22.8±1.58 kg m −2 ) and alcohol consumers in the upper quintile (22.7±1.53 kg m −2 ). Among normal-weight women, the risk of becoming overweight or obese over a 7-year follow-up period was 35% or 88% lower, respectively, for women in the upper quintile of alcohol intake relative to abstainers (hazard ratio (HR), 0.65; 95% confidence interval (CI), 0.58–0.73; or HR, 0.12; 95% CI, 0.05–0.25, respectively). Risk for overweight and obesity was not significantly modified by age. Wine consumption showed the greatest protective association for risk of overweight (HR, 0.75; 95% CI, 0.68–0.84), followed by liquor (HR, 0.85; 95% CI, 0.78–0.93) and beer (HR, 0.90; 95% CI, 0.82–1.00). Conclusion: Postmenopausal women of normal weight who report moderate alcohol intake have a reduced risk of becoming overweight or obese over time. Perhaps, weight control measures in this population should target behaviors other than reduction in alcohol for those of normal BMI consuming moderate amounts.</description><identifier>ISSN: 0307-0565</identifier><identifier>EISSN: 1476-5497</identifier><identifier>DOI: 10.1038/ijo.2012.84</identifier><identifier>PMID: 22689071</identifier><identifier>CODEN: IJOBDP</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/699/2743/393 ; 692/700/478/174 ; Age ; Aged ; Alcohol ; Alcohol Drinking - adverse effects ; Alcohol Drinking - epidemiology ; Alcohol Drinking - prevention &amp; control ; Alcohol use ; Alcoholic beverages ; Biological and medical sciences ; Body mass ; Body Mass Index ; Body weight ; Clinical trials ; Cohort Studies ; Diet ; Drinking of alcoholic beverages ; Endocrine therapy ; Enrollments ; Epidemiology ; Estrogens ; Female ; Females ; geriatric-original-article ; Health aspects ; Health care ; Health Promotion ; Health Promotion and Disease Prevention ; Humans ; Incidence ; Internal Medicine ; Medical sciences ; Medicine ; Medicine &amp; Public Health ; Metabolic Diseases ; Middle Aged ; Obesity ; Obesity - epidemiology ; Obesity - prevention &amp; control ; Overweight ; Post-menopause ; Postmenopausal women ; Postmenopause ; Preventive medicine ; Prospective Studies ; Public Health ; Risk Factors ; Risk reduction ; Risk Reduction Behavior ; Surveys and Questionnaires ; United States - epidemiology ; Vitaceae ; Weight control ; Wines ; Women's Health ; Womens health</subject><ispartof>International Journal of Obesity, 2012-09, Vol.36 (9), p.1158-1164</ispartof><rights>Macmillan Publishers Limited 2012</rights><rights>2015 INIST-CNRS</rights><rights>COPYRIGHT 2012 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Sep 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c618t-ede8ecda902842baa0c04104ac199184d7ec713784ef71a8e204183f84eb9a1a3</citedby><cites>FETCH-LOGICAL-c618t-ede8ecda902842baa0c04104ac199184d7ec713784ef71a8e204183f84eb9a1a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/ijo.2012.84$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/ijo.2012.84$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=26313813$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22689071$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thomson, C A</creatorcontrib><creatorcontrib>Wertheim, B C</creatorcontrib><creatorcontrib>Hingle, M</creatorcontrib><creatorcontrib>Wang, L</creatorcontrib><creatorcontrib>Neuhouser, M L</creatorcontrib><creatorcontrib>Gong, Z</creatorcontrib><creatorcontrib>Garcia, L</creatorcontrib><creatorcontrib>Stefanick, M L</creatorcontrib><creatorcontrib>Manson, J E</creatorcontrib><title>Alcohol consumption and body weight change in postmenopausal women: results from the Women's Health Initiative</title><title>International Journal of Obesity</title><addtitle>Int J Obes</addtitle><addtitle>Int J Obes (Lond)</addtitle><description>Objective: To determine whether alcohol consumption is associated with incident overweight or obesity in normal-weight, postmenopausal women. Design: Prospective cohort study considering baseline alcohol consumption and subsequent weight change over 7 years. Subjects: 15 920 normal-weight (body mass index (BMI): 18.5 to &lt;25 kg m −2 ), postmenopausal women enrolled in the Women′s Health Initiative Clinical Trial. Measurements: Body weight change, and incident overweight and obesity (BMI, 25.0 to &lt;30 and ⩾30 kg m −2 ) over 7 years. Results: One-third of the 13 822 women included in the analytical cohort reported no alcohol consumption. BMI differed little between abstainers (22.8±1.58 kg m −2 ) and alcohol consumers in the upper quintile (22.7±1.53 kg m −2 ). Among normal-weight women, the risk of becoming overweight or obese over a 7-year follow-up period was 35% or 88% lower, respectively, for women in the upper quintile of alcohol intake relative to abstainers (hazard ratio (HR), 0.65; 95% confidence interval (CI), 0.58–0.73; or HR, 0.12; 95% CI, 0.05–0.25, respectively). Risk for overweight and obesity was not significantly modified by age. Wine consumption showed the greatest protective association for risk of overweight (HR, 0.75; 95% CI, 0.68–0.84), followed by liquor (HR, 0.85; 95% CI, 0.78–0.93) and beer (HR, 0.90; 95% CI, 0.82–1.00). Conclusion: Postmenopausal women of normal weight who report moderate alcohol intake have a reduced risk of becoming overweight or obese over time. Perhaps, weight control measures in this population should target behaviors other than reduction in alcohol for those of normal BMI consuming moderate amounts.</description><subject>692/699/2743/393</subject><subject>692/700/478/174</subject><subject>Age</subject><subject>Aged</subject><subject>Alcohol</subject><subject>Alcohol Drinking - adverse effects</subject><subject>Alcohol Drinking - epidemiology</subject><subject>Alcohol Drinking - prevention &amp; control</subject><subject>Alcohol use</subject><subject>Alcoholic beverages</subject><subject>Biological and medical sciences</subject><subject>Body mass</subject><subject>Body Mass Index</subject><subject>Body weight</subject><subject>Clinical trials</subject><subject>Cohort Studies</subject><subject>Diet</subject><subject>Drinking of alcoholic beverages</subject><subject>Endocrine therapy</subject><subject>Enrollments</subject><subject>Epidemiology</subject><subject>Estrogens</subject><subject>Female</subject><subject>Females</subject><subject>geriatric-original-article</subject><subject>Health aspects</subject><subject>Health care</subject><subject>Health Promotion</subject><subject>Health Promotion and Disease Prevention</subject><subject>Humans</subject><subject>Incidence</subject><subject>Internal Medicine</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Metabolic Diseases</subject><subject>Middle Aged</subject><subject>Obesity</subject><subject>Obesity - epidemiology</subject><subject>Obesity - prevention &amp; control</subject><subject>Overweight</subject><subject>Post-menopause</subject><subject>Postmenopausal women</subject><subject>Postmenopause</subject><subject>Preventive medicine</subject><subject>Prospective Studies</subject><subject>Public Health</subject><subject>Risk Factors</subject><subject>Risk reduction</subject><subject>Risk Reduction Behavior</subject><subject>Surveys and Questionnaires</subject><subject>United States - epidemiology</subject><subject>Vitaceae</subject><subject>Weight control</subject><subject>Wines</subject><subject>Women's Health</subject><subject>Womens health</subject><issn>0307-0565</issn><issn>1476-5497</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkt2L1DAQwIMo3rr65LsExA_Qrkmbtqlvy6HewYEvio9lNp1us6TJmqQe99-b3q7enfoggYSZ-c1kvgh5ytmKs0K-0zu3yhnPV1LcIwsu6iorRVPfJwtWsDpjZVWekEch7BhjZcnyh-QkzyvZsJoviF0b5QZnqHI2TOM-amcp2I5uXHdFL1Fvh0jVAHaLVFu6dyGOaN0epgCGXrokvKcew2RioL13I40D0m-z_lWgZwgmDvTc6qgh6h_4mDzowQR8cnyX5OvHD19Oz7KLz5_OT9cXmaq4jBl2KFF10LBcinwDwBQTnAlQvGm4FF2NquZFLQX2NQeJeTLLok_ypgEOxZK8PsTde_d9whDbUQeFxoBFN4WWs6YQokz3f6BFYqsixV-S53-gOzd5mwqZKdmk5GR9Q23BYKtt76IHNQdt1wUrSsFYNcda_YNKp8NRp2Fgr5P-jsPLWw7DdWeDM9M8sXAXfHMAlXcheOzbvdcj-KuU5HWebdqYdt6YVopEPzvWNG1G7H6zv1YkAS-OAAQFpvdglQ43XOpMIfncx7cHLiRTWhd_uzl___sTz7DUzw</recordid><startdate>20120901</startdate><enddate>20120901</enddate><creator>Thomson, C A</creator><creator>Wertheim, B C</creator><creator>Hingle, M</creator><creator>Wang, L</creator><creator>Neuhouser, M L</creator><creator>Gong, Z</creator><creator>Garcia, L</creator><creator>Stefanick, M L</creator><creator>Manson, J E</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T2</scope><scope>7TK</scope><scope>7TS</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>7U1</scope><scope>7U2</scope></search><sort><creationdate>20120901</creationdate><title>Alcohol consumption and body weight change in postmenopausal women: results from the Women's Health Initiative</title><author>Thomson, C A ; 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Design: Prospective cohort study considering baseline alcohol consumption and subsequent weight change over 7 years. Subjects: 15 920 normal-weight (body mass index (BMI): 18.5 to &lt;25 kg m −2 ), postmenopausal women enrolled in the Women′s Health Initiative Clinical Trial. Measurements: Body weight change, and incident overweight and obesity (BMI, 25.0 to &lt;30 and ⩾30 kg m −2 ) over 7 years. Results: One-third of the 13 822 women included in the analytical cohort reported no alcohol consumption. BMI differed little between abstainers (22.8±1.58 kg m −2 ) and alcohol consumers in the upper quintile (22.7±1.53 kg m −2 ). Among normal-weight women, the risk of becoming overweight or obese over a 7-year follow-up period was 35% or 88% lower, respectively, for women in the upper quintile of alcohol intake relative to abstainers (hazard ratio (HR), 0.65; 95% confidence interval (CI), 0.58–0.73; or HR, 0.12; 95% CI, 0.05–0.25, respectively). Risk for overweight and obesity was not significantly modified by age. Wine consumption showed the greatest protective association for risk of overweight (HR, 0.75; 95% CI, 0.68–0.84), followed by liquor (HR, 0.85; 95% CI, 0.78–0.93) and beer (HR, 0.90; 95% CI, 0.82–1.00). Conclusion: Postmenopausal women of normal weight who report moderate alcohol intake have a reduced risk of becoming overweight or obese over time. Perhaps, weight control measures in this population should target behaviors other than reduction in alcohol for those of normal BMI consuming moderate amounts.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>22689071</pmid><doi>10.1038/ijo.2012.84</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
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subjects 692/699/2743/393
692/700/478/174
Age
Aged
Alcohol
Alcohol Drinking - adverse effects
Alcohol Drinking - epidemiology
Alcohol Drinking - prevention & control
Alcohol use
Alcoholic beverages
Biological and medical sciences
Body mass
Body Mass Index
Body weight
Clinical trials
Cohort Studies
Diet
Drinking of alcoholic beverages
Endocrine therapy
Enrollments
Epidemiology
Estrogens
Female
Females
geriatric-original-article
Health aspects
Health care
Health Promotion
Health Promotion and Disease Prevention
Humans
Incidence
Internal Medicine
Medical sciences
Medicine
Medicine & Public Health
Metabolic Diseases
Middle Aged
Obesity
Obesity - epidemiology
Obesity - prevention & control
Overweight
Post-menopause
Postmenopausal women
Postmenopause
Preventive medicine
Prospective Studies
Public Health
Risk Factors
Risk reduction
Risk Reduction Behavior
Surveys and Questionnaires
United States - epidemiology
Vitaceae
Weight control
Wines
Women's Health
Womens health
title Alcohol consumption and body weight change in postmenopausal women: results from the Women's Health Initiative
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