Unique ganglioside binding by botulinum neurotoxinsC and D-SA

The botulinum neurotoxins (BoNTs) are the most potent protein toxins for humans. There are seven serotypes of BoNTs (A-G), based on a lack of cross-antiserum neutralization. The BoNT/C and BoNT/D serotypes include mosaic toxins that are organized as D-C and C-D toxins. One BoNT D-C mosaic toxin, BoN...

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Veröffentlicht in:	The FEBS journal 2011-12, Vol.278 (23), p.4486-4496
Hauptverfasser:	Kroken, Abby R, Karalewitz, Andrew P.-A, Fu, Zhuji, Baldwin, Michael R, Kim, Jung-Ja P, Barbieri, Joseph T
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites Neurotoxicity Toxins
Online-Zugang:	Volltext
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