Twenty-Year Depressive Trajectories Among Older Women
CONTEXT Despite the frequent occurrence of depressive symptoms among older adults, especially women, little is known about the long-term course of late-life depressive symptoms. OBJECTIVE To characterize the natural course of depressive symptoms among older women (from the young old to the oldest ol...
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| Veröffentlicht in: | Archives of general psychiatry 2012-10, Vol.69 (10), p.1073-1079 |
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| creator | Byers, Amy L Vittinghoff, Eric Lui, Li-Yung Hoang, Tina Blazer, Dan G Covinsky, Kenneth E Ensrud, Kristine E Cauley, Jane A Hillier, Teresa A Fredman, Lisa Yaffe, Kristine |
| description | CONTEXT Despite the frequent occurrence of depressive symptoms among older adults, especially women, little is known about the long-term course of late-life depressive symptoms. OBJECTIVE To characterize the natural course of depressive symptoms among older women (from the young old to the oldest old) followed up for almost 20 years. DESIGN Using latent-class growth-curve analysis, we analyzed women enrolled in an ongoing prospective cohort study (1988 through 2009). SETTING Clinic sites in Baltimore, Maryland; Minneapolis, Minnesota; the Monongahela Valley near Pittsburgh, Pennsylvania; and Portland, Oregon. PARTICIPANTS We studied 7240 community-dwelling women 65 years or older. MAIN OUTCOME MEASURE The Geriatric Depression Scale short form (score range, 0-15) was used to routinely assess depressive symptoms during the follow-up period. RESULTS Among older women, we identified 4 latent classes during 20 years, with the predicted probabilities of group membership totaling 27.8% with minimal depressive symptoms, 54.0% with persistently low depressive symptoms, 14.8% with increasing depressive symptoms, and 3.4% with persistently high depressive symptoms. In an adjusted model for latent class membership, odds ratios (ORs) for belonging in the increasing depressive symptoms and persistently high depressive symptoms classes, respectively, compared with a group having minimal depressive symptoms were substantially and significantly (P |
| doi_str_mv | 10.1001/archgenpsychiatry.2012.43 |
| format | Article |
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OBJECTIVE To characterize the natural course of depressive symptoms among older women (from the young old to the oldest old) followed up for almost 20 years. DESIGN Using latent-class growth-curve analysis, we analyzed women enrolled in an ongoing prospective cohort study (1988 through 2009). SETTING Clinic sites in Baltimore, Maryland; Minneapolis, Minnesota; the Monongahela Valley near Pittsburgh, Pennsylvania; and Portland, Oregon. PARTICIPANTS We studied 7240 community-dwelling women 65 years or older. MAIN OUTCOME MEASURE The Geriatric Depression Scale short form (score range, 0-15) was used to routinely assess depressive symptoms during the follow-up period. RESULTS Among older women, we identified 4 latent classes during 20 years, with the predicted probabilities of group membership totaling 27.8% with minimal depressive symptoms, 54.0% with persistently low depressive symptoms, 14.8% with increasing depressive symptoms, and 3.4% with persistently high depressive symptoms. In an adjusted model for latent class membership, odds ratios (ORs) for belonging in the increasing depressive symptoms and persistently high depressive symptoms classes, respectively, compared with a group having minimal depressive symptoms were substantially and significantly (P < .05) elevated for the following variables: baseline smoking (ORs, 4.69 and 7.97), physical inactivity (ORs, 2.11 and 2.78), small social network (ORs, 3.24 and 6.75), physical impairment (ORs, 8.11 and 16.43), myocardial infarction (ORs, 2.09 and 2.41), diabetes mellitus (ORs, 2.98 and 3.03), and obesity (ORs, 1.86 and 2.90). CONCLUSIONS During 20 years, almost 20% of older women experienced persistently high depressive symptoms or increasing depressive symptoms. In addition, these women had more comorbidities, physical impairment, and negative lifestyle factors at baseline. These associations support the need for intervention and prevention strategies to reduce depressive symptoms into the oldest-old years.</description><identifier>ISSN: 0003-990X</identifier><identifier>EISSN: 1538-3636</identifier><identifier>DOI: 10.1001/archgenpsychiatry.2012.43</identifier><identifier>PMID: 23026957</identifier><identifier>CODEN: ARGPAQ</identifier><language>eng</language><publisher>Chicago, IL: American Medical Association</publisher><subject>Adult and adolescent clinical studies ; Aged ; Aging - psychology ; Baltimore - epidemiology ; Biological and medical sciences ; Depression ; Depressive Disorder - classification ; Depressive Disorder - epidemiology ; Female ; Geriatric Assessment ; Humans ; Medical sciences ; Minnesota - epidemiology ; Mood disorders ; Oregon - epidemiology ; Pennsylvania - epidemiology ; Prospective Studies ; Psychiatric Status Rating Scales ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Time Factors</subject><ispartof>Archives of general psychiatry, 2012-10, Vol.69 (10), p.1073-1079</ispartof><rights>2015 INIST-CNRS</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a417t-24f034dbc42ab7d326ef5ccbd654375bf95a6dca098e365af89df9722b91dfed3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jamanetwork.com/journals/jamapsychiatry/articlepdf/10.1001/archgenpsychiatry.2012.43$$EPDF$$P50$$Gama$$H</linktopdf><linktohtml>$$Uhttps://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/archgenpsychiatry.2012.43$$EHTML$$P50$$Gama$$H</linktohtml><link.rule.ids>64,314,777,781,3327,27905,27906,76238,76241</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26442127$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23026957$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Byers, Amy L</creatorcontrib><creatorcontrib>Vittinghoff, Eric</creatorcontrib><creatorcontrib>Lui, Li-Yung</creatorcontrib><creatorcontrib>Hoang, Tina</creatorcontrib><creatorcontrib>Blazer, Dan G</creatorcontrib><creatorcontrib>Covinsky, Kenneth E</creatorcontrib><creatorcontrib>Ensrud, Kristine E</creatorcontrib><creatorcontrib>Cauley, Jane A</creatorcontrib><creatorcontrib>Hillier, Teresa A</creatorcontrib><creatorcontrib>Fredman, Lisa</creatorcontrib><creatorcontrib>Yaffe, Kristine</creatorcontrib><title>Twenty-Year Depressive Trajectories Among Older Women</title><title>Archives of general psychiatry</title><addtitle>Arch Gen Psychiatry</addtitle><description>CONTEXT Despite the frequent occurrence of depressive symptoms among older adults, especially women, little is known about the long-term course of late-life depressive symptoms. OBJECTIVE To characterize the natural course of depressive symptoms among older women (from the young old to the oldest old) followed up for almost 20 years. DESIGN Using latent-class growth-curve analysis, we analyzed women enrolled in an ongoing prospective cohort study (1988 through 2009). SETTING Clinic sites in Baltimore, Maryland; Minneapolis, Minnesota; the Monongahela Valley near Pittsburgh, Pennsylvania; and Portland, Oregon. PARTICIPANTS We studied 7240 community-dwelling women 65 years or older. MAIN OUTCOME MEASURE The Geriatric Depression Scale short form (score range, 0-15) was used to routinely assess depressive symptoms during the follow-up period. RESULTS Among older women, we identified 4 latent classes during 20 years, with the predicted probabilities of group membership totaling 27.8% with minimal depressive symptoms, 54.0% with persistently low depressive symptoms, 14.8% with increasing depressive symptoms, and 3.4% with persistently high depressive symptoms. In an adjusted model for latent class membership, odds ratios (ORs) for belonging in the increasing depressive symptoms and persistently high depressive symptoms classes, respectively, compared with a group having minimal depressive symptoms were substantially and significantly (P < .05) elevated for the following variables: baseline smoking (ORs, 4.69 and 7.97), physical inactivity (ORs, 2.11 and 2.78), small social network (ORs, 3.24 and 6.75), physical impairment (ORs, 8.11 and 16.43), myocardial infarction (ORs, 2.09 and 2.41), diabetes mellitus (ORs, 2.98 and 3.03), and obesity (ORs, 1.86 and 2.90). CONCLUSIONS During 20 years, almost 20% of older women experienced persistently high depressive symptoms or increasing depressive symptoms. In addition, these women had more comorbidities, physical impairment, and negative lifestyle factors at baseline. These associations support the need for intervention and prevention strategies to reduce depressive symptoms into the oldest-old years.</description><subject>Adult and adolescent clinical studies</subject><subject>Aged</subject><subject>Aging - psychology</subject><subject>Baltimore - epidemiology</subject><subject>Biological and medical sciences</subject><subject>Depression</subject><subject>Depressive Disorder - classification</subject><subject>Depressive Disorder - epidemiology</subject><subject>Female</subject><subject>Geriatric Assessment</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Minnesota - epidemiology</subject><subject>Mood disorders</subject><subject>Oregon - epidemiology</subject><subject>Pennsylvania - epidemiology</subject><subject>Prospective Studies</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Time Factors</subject><issn>0003-990X</issn><issn>1538-3636</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpl0MlKA0EQBuBGFBOXF_Ag40HwMrH3SR-DOwheIuppqOmu1gmzxO6Jkrd3QqI5eCoKvr8KfkLOGB0xStklBPvxjs08Lu1HCV1YjjhlfCTFDhkyJcap0ELvkiGlVKTG0NcBOYhx1q9Uab5PBlxQro3KhkRNv7HplukbQkiucR4wxvILk2mAGdquDSXGZFK3zXvyVDkMyUtbY3NE9jxUEY8385A8395Mr-7Tx6e7h6vJYwqSZV3KpadCusJKDkXmBNfolbWF00qKTBXeKNDOAjVjFFqBHxvnTcZ5YZjz6MQhuVjfnYf2c4Gxy-syWqwqaLBdxJzRMedCZxntqVlTG9oYA_p8HsoawrJH-aq1_F9r-aq1XIo-e7p5syhqdH_J35p6cL4BEC1UPkBjy7h1WkrO-MqdrB3UsP0vMqoZEz9tl4QH</recordid><startdate>20121001</startdate><enddate>20121001</enddate><creator>Byers, Amy L</creator><creator>Vittinghoff, Eric</creator><creator>Lui, Li-Yung</creator><creator>Hoang, Tina</creator><creator>Blazer, Dan G</creator><creator>Covinsky, Kenneth E</creator><creator>Ensrud, Kristine E</creator><creator>Cauley, Jane A</creator><creator>Hillier, Teresa A</creator><creator>Fredman, Lisa</creator><creator>Yaffe, Kristine</creator><general>American Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20121001</creationdate><title>Twenty-Year Depressive Trajectories Among Older Women</title><author>Byers, Amy L ; Vittinghoff, Eric ; Lui, Li-Yung ; Hoang, Tina ; Blazer, Dan G ; Covinsky, Kenneth E ; Ensrud, Kristine E ; Cauley, Jane A ; Hillier, Teresa A ; Fredman, Lisa ; Yaffe, Kristine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a417t-24f034dbc42ab7d326ef5ccbd654375bf95a6dca098e365af89df9722b91dfed3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult and adolescent clinical studies</topic><topic>Aged</topic><topic>Aging - psychology</topic><topic>Baltimore - epidemiology</topic><topic>Biological and medical sciences</topic><topic>Depression</topic><topic>Depressive Disorder - classification</topic><topic>Depressive Disorder - epidemiology</topic><topic>Female</topic><topic>Geriatric Assessment</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Minnesota - epidemiology</topic><topic>Mood disorders</topic><topic>Oregon - epidemiology</topic><topic>Pennsylvania - epidemiology</topic><topic>Prospective Studies</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Time Factors</topic><toplevel>online_resources</toplevel><creatorcontrib>Byers, Amy L</creatorcontrib><creatorcontrib>Vittinghoff, Eric</creatorcontrib><creatorcontrib>Lui, Li-Yung</creatorcontrib><creatorcontrib>Hoang, Tina</creatorcontrib><creatorcontrib>Blazer, Dan G</creatorcontrib><creatorcontrib>Covinsky, Kenneth E</creatorcontrib><creatorcontrib>Ensrud, Kristine E</creatorcontrib><creatorcontrib>Cauley, Jane A</creatorcontrib><creatorcontrib>Hillier, Teresa A</creatorcontrib><creatorcontrib>Fredman, Lisa</creatorcontrib><creatorcontrib>Yaffe, Kristine</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of general psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Byers, Amy L</au><au>Vittinghoff, Eric</au><au>Lui, Li-Yung</au><au>Hoang, Tina</au><au>Blazer, Dan G</au><au>Covinsky, Kenneth E</au><au>Ensrud, Kristine E</au><au>Cauley, Jane A</au><au>Hillier, Teresa A</au><au>Fredman, Lisa</au><au>Yaffe, Kristine</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Twenty-Year Depressive Trajectories Among Older Women</atitle><jtitle>Archives of general psychiatry</jtitle><addtitle>Arch Gen Psychiatry</addtitle><date>2012-10-01</date><risdate>2012</risdate><volume>69</volume><issue>10</issue><spage>1073</spage><epage>1079</epage><pages>1073-1079</pages><issn>0003-990X</issn><eissn>1538-3636</eissn><coden>ARGPAQ</coden><abstract>CONTEXT Despite the frequent occurrence of depressive symptoms among older adults, especially women, little is known about the long-term course of late-life depressive symptoms. OBJECTIVE To characterize the natural course of depressive symptoms among older women (from the young old to the oldest old) followed up for almost 20 years. DESIGN Using latent-class growth-curve analysis, we analyzed women enrolled in an ongoing prospective cohort study (1988 through 2009). SETTING Clinic sites in Baltimore, Maryland; Minneapolis, Minnesota; the Monongahela Valley near Pittsburgh, Pennsylvania; and Portland, Oregon. PARTICIPANTS We studied 7240 community-dwelling women 65 years or older. MAIN OUTCOME MEASURE The Geriatric Depression Scale short form (score range, 0-15) was used to routinely assess depressive symptoms during the follow-up period. RESULTS Among older women, we identified 4 latent classes during 20 years, with the predicted probabilities of group membership totaling 27.8% with minimal depressive symptoms, 54.0% with persistently low depressive symptoms, 14.8% with increasing depressive symptoms, and 3.4% with persistently high depressive symptoms. In an adjusted model for latent class membership, odds ratios (ORs) for belonging in the increasing depressive symptoms and persistently high depressive symptoms classes, respectively, compared with a group having minimal depressive symptoms were substantially and significantly (P < .05) elevated for the following variables: baseline smoking (ORs, 4.69 and 7.97), physical inactivity (ORs, 2.11 and 2.78), small social network (ORs, 3.24 and 6.75), physical impairment (ORs, 8.11 and 16.43), myocardial infarction (ORs, 2.09 and 2.41), diabetes mellitus (ORs, 2.98 and 3.03), and obesity (ORs, 1.86 and 2.90). CONCLUSIONS During 20 years, almost 20% of older women experienced persistently high depressive symptoms or increasing depressive symptoms. In addition, these women had more comorbidities, physical impairment, and negative lifestyle factors at baseline. These associations support the need for intervention and prevention strategies to reduce depressive symptoms into the oldest-old years.</abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>23026957</pmid><doi>10.1001/archgenpsychiatry.2012.43</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult and adolescent clinical studies Aged Aging - psychology Baltimore - epidemiology Biological and medical sciences Depression Depressive Disorder - classification Depressive Disorder - epidemiology Female Geriatric Assessment Humans Medical sciences Minnesota - epidemiology Mood disorders Oregon - epidemiology Pennsylvania - epidemiology Prospective Studies Psychiatric Status Rating Scales Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Time Factors |
| title | Twenty-Year Depressive Trajectories Among Older Women |
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