Resolvins D1, D2, and Other Mediators of Self-Limited Resolution of Inflammation in Human Blood following n-3 Fatty Acid Supplementation

Resolvins and protectins are families of local lipid mediators generated from the n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) during self-limited resolution of inflammation. We aimed to develop a liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay to measur...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2012-10, Vol.58 (10), p.1476-1484
Hauptverfasser:	MAS, Emilie, CROFT, Kevin D, ZAHRA, Paul, BARDEN, Anne, MORI, Trevor A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analytical, structural and metabolic biochemistry Biological and medical sciences Blood Chromatography, Liquid Dietary Supplements Docosahexaenoic Acids - administration & dosage Docosahexaenoic Acids - blood Docosahexaenoic Acids - chemistry Eicosapentaenoic Acid - administration & dosage Eicosapentaenoic Acid - blood Eicosapentaenoic Acid - chemistry Fatty acids Female Fundamental and applied biological sciences. Psychology Humans Inflammation - blood Inflammatory bowel disease Investigative techniques, diagnostic techniques (general aspects) Liquid chromatography Male Mass spectrometry Medical sciences Middle Aged Molecular biophysics Pain Plasma Rodents Stereoisomerism Tandem Mass Spectrometry
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