Dendritic cell vaccine modified by Ag85A gene enhances anti-tumor immunity against bladder cancer

The ability of dendritic cells to provide all the signals required for T-cell activation makes them an ideal cancer vaccine platform. With the use of established DC2.4 cell line, originated from C57BL/6 mice and developed by superinfecting GM-CSF transduced bone marrow cells with myc and raf oncogen...

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Veröffentlicht in:	International immunopharmacology 2012-11, Vol.14 (3), p.252-260
Hauptverfasser:	Zhang, Pei, Wang, Jinyan, Wang, Danan, Wang, Huan, Shan, Fengping, Chen, Liudan, Hou, Ying, Wang, Enhua, Lu, Chang-long
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyltransferases - genetics Ag85A Animals Antigens, Bacterial - genetics Biological and medical sciences Bladder cancer Cancer Vaccines Cell Line Cell Line, Tumor Cell Proliferation Dendritic cells Dendritic Cells - immunology Immunotherapy Medical sciences Mice Mice, Inbred C57BL Nephrology. Urinary tract diseases Pharmacology. Drug treatments T-Lymphocytes - immunology Tumors of the urinary system Urinary Bladder Neoplasms - immunology Urinary Bladder Neoplasms - therapy Urinary system involvement in other diseases. Miscellaneous Urinary tract. Prostate gland Vaccine
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